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排序方式: 共有428条查询结果,搜索用时 883 毫秒
1.
Dao  Ha Viet  Takata  Yoshinobu  Omura  Takuo  Sato  Shigeru  Fukuyo  Yasuwo  Kodama  Masaaki 《Fisheries Science》2009,75(2):507-512
Previously we reported that a significant level of domoic acid, a causative toxin for amnesic shellfish poisoning, was detected in bivalves belonging to a genus Spondylus from various tropical Asian countries. These findings indicate that causative plankton species for domoic acid widely distribute in these areas. In the present study, we monitored seasonal change of domoic acid level of Spondylus versicolor in association with that of plankton samples in Nha Phu Bay, Khanh Hoa, Vietnam from December 2004 to October 2005. The toxicity of S. versicolor showed distinct seasonal variation. During the period when domoic acid level of S. versicolor was increasing, a significant level of domoic acid was detected in the plankton samples, showing the correlation between these two parameters. These findings show that plankton causative for domoic acid occurred in the bay, and S. versicolor accumulate domoic acid during a bloom of the toxic plankton by food web transfer.  相似文献   
2.
The 1918 influenza pandemic resulted in about 20 million deaths. This enormous impact, coupled with renewed interest in emerging infections, makes characterization of the virus involved a priority. Receptor binding, the initial event in virus infection, is a major determinant of virus transmissibility that, for influenza viruses, is mediated by the hemagglutinin (HA) membrane glycoprotein. We have determined the crystal structures of the HA from the 1918 virus and two closely related HAs in complex with receptor analogs. They explain how the 1918 HA, while retaining receptor binding site amino acids characteristic of an avian precursor HA, is able to bind human receptors and how, as a consequence, the virus was able to spread in the human population.  相似文献   
3.
    
Lectin is a carbohydrate-binding protein that recognizes specific cells by binding to cell-surface polysaccharides. Tumor cells generally show various glycosylation patterns, making them distinguishable from non-cancerous cells. Consequently, lectin has been suggested as a good anticancer agent. Herein, the anticancer activity of Bryopsis plumosa lectins (BPL1, BPL2, and BPL3) was screened and tested against lung cancer cell lines (A549, H460, and H1299). BPL2 showed high anticancer activity compared to BPL1 and BPL3. Cell viability was dependent on BPL2 concentration and incubation time. The IC50 value for lung cancer cells was 50 μg/mL after 24 h of incubation in BPL2 containing medium; however, BPL2 (50 μg/mL) showed weak toxicity in non-cancerous cells (MRC5). BPL2 affected cancer cell growth while non-cancerous cells were less affected. Further, BPL2 (20 μg/mL) inhibited cancer cell invasion and migration (rates were ˂20%). BPL2 induced the downregulation of epithelial-to-mesenchymal transition-related genes (Zeb1, vimentin, and Twist). Co-treatment with BPL2 and gefitinib (10 μg/mL and 10 μM, respectively) showed a synergistic effect compared with monotherapy. BPL2 or gefitinib monotherapy resulted in approximately 90% and 70% cell viability, respectively, with concomitant treatment showing 40% cell viability. Overall, BPL2 can be considered a good candidate for development into an anticancer agent.  相似文献   
4.
Plant Foods for Human Nutrition - Bitter gourd fruits contain high amounts of charantin, stigmasterol glucoside and β-sitosterol glucoside, which have been shown to provide health benefits for...  相似文献   
5.
    
Failure of concrete irrigation canal linings in the form of cracking, rupture, uplifting and opening of joints, causes loss of water and money in many countries. Following the appearance of extensive cracking of concrete linings in one of the Shoeybieh sugar cane industry farms in the Khoozestan province of Iran, extensive research work was conducted to identify the main causes. In this paper, the final results of the research are presented. The testing program consisted of laboratory as well as field tests, including identification, chemical and mechanical tests of soil samples taken from the borrow pits and canal embankments. Dispersivity tests were performed using pin‐hole and chemical methods. Swelling tests were conducted using the ASTM standard and ISSMFE method. The field test includes measurement of deformations of the concrete lining and embankment of an actual lined canal resulting from the filling of the canal with water. The canal was 60 m in length. The deformations were recorded by surveying the elevations of steel bars driven to different depths under the canal lining and at different points in the canal and its embankment sections. The results of laboratory tests showed the soil to have low to medium plasticity with a classification of CL‐ML, having less than 1% soluble content, and being nondispersive. Swelling tests conducted by the ASTM and ISSMFE methods showed completely different results. The ISSMFE method resulted in a high free swell potential, while the ASTM method indicated a low to medium potential. The results of full‐scale field tests were all in favor of the ISSMFE method. The greatest difference between the results of the two methods was found to be due to the different compaction methods used during construction of the canal, as well as the moisture content of the soil sample being prepared for the swell tests. The flocculent structure and lower compaction water content of soil samples in the ISSMFE method resulted in much higher free swell. The similarity between compaction methods used in the field and the static effort used in the ISSMFE method, as well as very low soil water content of the canal embankments during lining operations, were found to be the main reasons for swelling of the soil and the eventual cracking of the concrete linings. Copyright © 2002 John Wiley & Sons, Ltd.  相似文献   
6.
    
Tilapia lake virus (TiLV) is an emerging pathogen in aquaculture, reportedly affecting farmed tilapia in 16 countries across multiple continents. Following an early warning in 2017 that TiLV might be widespread, we executed a surveillance programme on tilapia grow-out farms and hatcheries from 10 districts of Bangladesh in 2017 and 2019. Among farms experiencing unusual mortality, eight out of 11 farms tested positive for TiLV in 2017, and two out of seven tested positive in 2019. Investigation of asymptomatic broodstock collected from 16 tilapia hatcheries revealed that six hatcheries tested positive for TiLV. Representative samples subjected to histopathology confirmed pathognomonic lesions of syncytial hepatitis. We recovered three complete genomes of TiLV from infected fish, one from 2017 and two from 2019. Phylogenetic analyses based on both the concatenated coding sequences of 10 segments and only segment 1 consistently revealed that Bangladeshi TiLV isolates formed a unique cluster within Thai clade, suggesting a close genetic relation. In summary, this study revealed the circulation of TiLV in 10 farms and six hatcheries located in eight districts of Bangladesh. We recommend continuing TiLV-targeted surveillance efforts to identify contaminated sources to minimize the countrywide spread and severity of TiLV infection.  相似文献   
7.
Abalones ( Haliotis species) are a popular delicacy and commonly preserved in dried form either whole or in slices or small pieces for consumption in Asian countries. Driven by the huge profit from trading abalones, dishonest traders may substitute other molluscan species for processed abalone, of which the morphological characteristics are frequently lost in the processed form. For protection of consumer rights and law enforcement against fraud, there is a need for an effective methodology to differentiate between fake and genuine abalone. This paper describes a method (validated according to the international forensic guidelines provided by SWGDAM) for the identification of fake abalone species using forensically informative nucleotide sequence (FINS) analysis. A study of the local market revealed that many claimed "abalone slice" samples on sale are not genuine. The fake abalone samples were found to be either volutids of the genus Cymbium (93%) or the muricid Concholepas concholepas (7%). This is the first report of Cymbium species being used for the preparation and sale as "abalone" in dried sliced form in Hong Kong.  相似文献   
8.
介绍应用国际互联网传播森林景观信息和网上旅游服务概况,论述了森林景观数字信息的几种计算机实现方法,并展望森林景观信息网络化前景。  相似文献   
9.
This study was conducted to evaluate the growth characteristics and fatty acid composition among 15 kenaf mutants derived from the kenaf germplasm C14 and 15 kenaf accessions originating from Russia, India, China, Iran, and Italy. The overall growth performance (plant height, stem diameter, flowering date, leaf, and flower size) of the stem color mutant lines derived from C14 are similar to those of the original variety. However, the flower color mutant lines derived from C14 showed flowering to occur 10 days later when compared with the original variety and showed smaller leaf sizes than the original variety. Late-ripened kenaf accessions (Jinju, Auxu, and Jnagdae) can yield more bio-mass compared with early or medium-maturing germplasm. The late maturity kenaf (Auxu, Jinju, and Jangdae) has a higher oil percentage than the early maturity germplasm. Linoleic, oleic, and palmitic acids were the predominant fatty acids in all kenaf seeds. The stem color mutant lines significantly surpassed the parental means of all saturated fatty acids. In addition, the flower color mutant lines showed broad ranges of variation in oleic acid. The 15 accessions showed a wide range of fatty acid compositions, spanning from 29.75 to 38.30% saturated fatty acids and 61.70 to 70.24% total unsaturated fatty acids, and the late maturity kenaf has a higher linoleic acid percentage than the early maturity germplasm. The flowering period was highly positively (P ≤ 0.01) correlated with the plant height, stem diameter, oil percent, and linolenic acid (C18:3), and it was significantly negatively (P ≤ 0.01) correlated with stearic acid (C18:0). These results will provide valuable information to assist the parental selection of kenaf breeding.  相似文献   
10.
陈建兵  哈晓伟 《森林工程》1998,14(3):59-59,62
本文用壅水平衡原理对最一般情况下的一河多桥断面流量分配进行了分析,计算,结果表明,用壅水平原理计算一河多桥的断面流量分配是符合实际的。  相似文献   
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