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1.
Blood was obtained from 61 neonatal Holstein calves originating from a farm in Germany with a high incidence of bovine neonatal pancytopenia (BNP). In order to detect alterations that might be related to BNP, selected haematological analytes were determined. Haematological examinations demonstrated alterations in at least two of the three cell lineages in 10 calves (16.39 per cent). Six animals (9.84 per cent) developed a bleeding disorder indicative of BNP at approximately two weeks of age. None of these animals showed alterations in complete blood cell count at sampling in the first week of life. In weeks when calves with BNP were born, an increase in the number of apparently healthy calves demonstrating decreases in blood cell counts was observed. 相似文献
2.
Paula Janssen Gesine Barton Manfred Kietzmann Jessica Meißner 《Journal of veterinary science (Suw?n-si, Korea)》2022,23(2)
BackgroundAntibacterial agents play important roles in the treatment of bacterial infections. However, the development of antimicrobial resistance (AMR) and carry-over of substances into the environment are several problems arising during oral treatment of bacterial infections. We assessed AMR development in commensal Escherichia coli (E. coli) in enrofloxacin treated and untreated animals. In addition, we examined fluoroquinolone in the plasma and urine of treated and untreated animals, and in sedimentation dust and aerosol.MethodsIn each trial, six pigs were treated with enrofloxacin via powder, granulate or pellet forms in two time periods (days 1–5 and 22–26). Four pigs served as untreated controls. The minimum inhibitory concentration (MIC) was determined to evaluate AMR development. Analysis of enro- and ciprofloxacin was performed with high performance liquid chromatography.ResultsNon-wildtype E. coli (MIC > 0.125 µg/mL) was detected in the pellet treated group after the first treatment period, whereas in the other groups, non-wildtype isolates were found after the second treatment period. E. coli with MIC > 4 µg/mL was found in only the pellet trial. Untreated animals showed similar susceptibility shifts several days later. Bioavailability differed among the treatment forms (granulate > pellet > powder). Enro- and ciprofloxacin were detected in aerosols and sedimentation dust (granulate, powder > pellet).ConclusionsThis study indicates that the kind of the oral dosage form of antibiotics affects environmental contamination and AMR development in commensal E. coli in treated and untreated pigs. 相似文献
3.
P. Witt L. de Kroon N. Ankringa M. Delany L. W. L. van Bruggen R. van den Boom M. M. Sloet van Oldruitenborgh-Oosterbaan E. W. Siegers 《Equine Veterinary Education》2022,34(9):e369-e374
A 2-month-old Warmblood colt presented with recurrent colic and regurgitation. Gastroscopy, performed on several occasions, and barium-contrast radiography revealed severe squamous gastric ulceration and stenosis at the level of the margo plicatus. Treatment with omeprazole reduced the extent and severity of the gastric ulcers but did not affect the stenosis. The foal was euthanised because of a poor prognosis, and post-mortem examination confirmed the clinical diagnosis. Severe squamous gastric ulceration, granulation tissue formation and cicatrisation of deep gastric lesions were considered to have caused the stenosis. Gastroduodenal outflow obstruction is a recognised disorder in foals, but stenosis at the level of the margo plicatus has not been reported in foals or adult horses. To the authors' knowledge, this is the first case of severe squamous gastric ulceration, complicated by stenosis at the level of the margo plicatus, in a foal. Although rare, gastric stenosis should be considered in foals suffering recurrent colic and regurgitation. 相似文献
4.
Soil microbial biomass and nitrogen supply in an irrigated lowland rice soil as affected by crop rotation and residue management 总被引:5,自引:0,他引:5
C. Witt Kenneth G. Cassman Johannes C. G. Ottow Ulrich Biker 《Biology and Fertility of Soils》1998,28(1):71-80
Processes that govern the soil nitrogen (N) supply in irrigated lowland rice systems are poorly understood. The objectives
of this paper were to investigate the effects of crop rotation and management on soil N dynamics, microbial biomass C (CBIO) and microbial biomass N (NBIO) in relation to rice N uptake and yield. A maize-rice (M-R) rotation was compared with a rice-rice (R-R) double-cropping
system over a 2-year period with four cropping seasons. In the M-R system, maize (Zea mays L.) was grown in aerated soil during the dry season (DS) followed by rice (Oryza sativa L.) grown in flooded soil during the wet season (WS). In the R-R system, rice was grown in flooded soil in both the DS and
WS. Three fertilizer N rates (0, 50 or 100 kg urea-N ha–1 in WS) were assigned to subplots within the cropping system main plots. Early versus late crop residue incorporation following
DS maize or rice were established as additional treatments in sub-subplots in the second year. In the R-R system, the time
of residue incorporation had a large effect on NO3
–-N accumulation during the fallow period and also on extractable NH4
+-N, rice N uptake and yield in the subsequent cropping period. In contrast, time of residue incorporation had little influence
on extractable N in both the fallow and rice-cropping periods of the M-R system, and no detectable effects on rice N uptake
or yield. In both cropping systems, CBIO and NBIO were not sensitive to residue incorporation despite differences of 2- to 3-fold increase in the amount of incorporated residue
C and N, and were relatively insensitive to N fertilizer application. Extractable organic N was consistently greater after
mid-tillering in M-R compared to the R-R system across N rate and residue incorporation treatments, and much of this organic
N was α-amino N. We conclude that N mineralization-immobilization dynamics in lowland rice systems are sensitive to soil aeration
as influenced by residue management in the fallow period and crop rotation, and that these factors have agronomically significant
effects on rice N uptake and yield. Microbial biomass measurements, however, were a poor indicator of these dynamics.
Received: 31 October 1997 相似文献
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Panagiotis Mantis DVM Christopher R. Lamb MA VetMB Angela L. Witt DVM Reto Neiger Dr Med Vet PhD 《Veterinary radiology & ultrasound》2003,44(6):682-685
Trilostane, a 3beta-hydroxysteroid dehydrogenase inhibitor, has been used successfully over the last few years for the treatment of canine pituitary-dependent hyperadrenocorticism. In a prospective study of 19 dogs with pituitary-dependent hyperadrenocorticism, the adrenal glands were measured before and at least 6 months after initiation of trilostane therapy. Right adrenal gland length and caudal pole thickness and left adrenal gland caudal pole thickness increased significantly (p < or = 0.05); there was no significant change in left adrenal gland length. Enlargement of adrenal glands during trilostane therapy may occur as a result of suppression of the negative feedback mechanism affecting cortisol production. 相似文献
8.
V E Mendel M R Witt B S Gitchell D N Gribble Q R Rogers H J Segall H D Knight 《American journal of veterinary research》1988,49(4):572-578
Nine adult horses were fed alfalfa hay cubes containing approximately 10% Senecio vulgaris until all horses had consumed approximately the same amount of toxic components of S vulgaris, pyrrolizidine alkaloids (PA). The amount of PA consumed was determined by the amount that induced clinical signs of PA toxicosis in 3 horses. The 6 other horses were given similar amounts per kilogram of body weight. An initial decrease of feed intake was observed when horses' diets were changed from alfalfa cubes to alfalfa/Senecio cubes, and feed intake was decreased further over 89 to 98 days. From 50 to 159 days, body weight decreased in all horses. Liver disease was induced in all 9 horses after they ate an average of 233 +/- 9.2 mg of PA/kg of body weight. Eight horses died or were euthanatized. Treatment with branched chain amino acids had no effect on mortality, but appeared to reduce neurologic problems. Clinical signs of PA-induced liver disease included ataxia, head pressing, and decreased feed intake. Other clinical signs of toxicosis were observed individual horses, but did not develop in most horses. Megalocytic hepatopathy developed. Liver abnormalities proceeded as PA was consumed and were severe in 8 of 9 horses before clinical signs of toxicosis appeared. Sulfobromophthalein sodium clearance did not decrease until PA-induced liver disease was advanced. Bile acid (BA) concentrations increased to greater than or equal to 50 mumol/L, in the 8 horses that died. One horse had hepatopathy and increased BA concentration, but survived. In this horse, BA concentration peaked at 33 mumol/L and then decreased.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
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10.
OBJECTIVE: To describe a technique for laparoscopic-assisted removal of cystic calculi in geldings and report outcome. STUDY DESIGN: Clinical report. ANIMALS: Four geldings with cystic calculi. METHODS: Laparoscopic-assisted cystotomy and urolith retrieval was performed in 4 anesthetized geldings positioned in dorsal recumbency. With a laparoscope portal located at the umbilicus, the abdomen was insufflated and then the surgical table was tilted (30 degrees head-down position) before an instrumental portal was created parallel and 2-3 cm medial to the left external inguinal ring. Laparoscopic grasping forceps were inserted to grasp the cranial aspect of the bladder and elevate it to the ventral abdominal wall. With the instrumental portal as mid-point, the parainguinal skin incision was longitudinally extended cranial and caudal (approximately 8-10 cm) to accommodate the size of the urolith. The apex of the bladder was exteriorized and sharply incised, the urolith extracted, and after cystotomy closure, the bladder was repositioned. The mini-laparotomy and trocar incisions were closed in layers. RESULTS: There were no intra- or post-operative complications. All horses had minor incisional swelling for 3-4 days. No signs of abdominal or incisional pain were observed. Hematuria and slight stranguria occurred until the 3rd or 4th day. Surgical time (skin incision to skin closure) was 35-40 minutes. On long-term follow-up (up to 12 months) no recurrence of clinical signs associated with cystic calculi occurred. CONCLUSION: Uroliths (6-8 cm diameter) can be removed by laparoscopic-assisted cystotomy in geldings. CLINICAL RELEVANCE: Laparoscopic-assisted cystotomy combines the advantages of the parainguinal laparocystotomy with laparoscopic technique for removal of cystic calculi while avoiding their disadvantages. 相似文献