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1.
H M Syme J C Scott-Moncrieff N G Treadwell M F Thompson P W Snyder M R White J W Oliver 《Journal of the American Veterinary Medical Association》2001,219(12):1725-8, 1707-8
An 11-year-old spayed female Labrador Retriever and a 9-year-old castrated male miniature Poodle were evaluated because of clinical signs of hyperadrenocorticism. Cortisol testing did not support a diagnosis of hypercortisolemia in either dog; however, imaging studies revealed unilateral adrenal tumors in both dogs. Serum concentrations of 17-hydroxyprogesterone, progesterone, and estradiol were high in both dogs, and androstenedione concentrations were also high in 1 dog. It is suspected that sex hormone secretion by the adrenal tumors in these dogs resulted in clinical signs of hyperadrenocorticism. Clinical signs and hormonal abnormalities resolved in the male dog after surgical resection of the tumor. There was no improvement in clinical signs after treatment with mitotane in the female dog, which died 2 months after diagnosis. Histologic evaluation confirmed the presence of adrenocortical carcinoma in both dogs. 相似文献
2.
R. N. White 《The Journal of small animal practice》1995,36(4):151-158
The surgical repair of tracheal collapse in 25 dogs is described. The initial presenting signs included coughing, dyspnoea, gagging, retching, exercise intolerance, cyanosis and collapse. Diagnosis was based upon the clinical signs, plain radiography and tracheal endoscopy. The collapse was corrected by the application of a number of extraluminal polypropylene prosthetic rings applied to the affected trachea. Additionally, a left arytenoid lateralisation was also performed. The perioperative complication rate was approximately 4 per cent, while the success rate was 75 per cent. The technique reduces the likelihood of catastrophic postoperative complications associated with iatrogenic laryngeal paralysis which is a possible complication of placement of extraluminal tracheal support devices. 相似文献
3.
R. A. S. White 《The Journal of small animal practice》1989,30(10):543-549
Sixty-two dogs with laryngeal paralysis were presented over a three year period. Presenting clinical signs included inspiratory stridor (100 per cent), exercise intolerance or syncopal episodes (81 per cent), loss or alteration in phonation (48 per cent) and coughing or gagging when eating (29 per cent). Causes of the paralysis were determined as traumatic (two dogs), neoplastic (two dogs), iatrogenic (two dogs), congenital (one dog) and idiopathic (55 dogs). Unilateral arytenoid lateralisation was performed in all dogs. The perioperative complication rate was approximately 10 per cent, while the success rate as judged by owners one year postoperatively was greater than 90 per cent. The technique avoided many of the recorded complications of intralaryngeal surgery. Operative times were short and the requirement for postoperative monitoring was minimal. Increasing familiarity with the technique favourably influenced the incidence of complications and the success rate. 相似文献
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The structure of the shell of the egg of Trichuris trichiura was examined using light microscopy as well as scanning and transmission electron microscopy. The results confirmed its three-layered structure and provided evidence that the cores of the polar plugs, which could be seen to be extensions of the shell's middle layer, could be lost en bloc, either mechanically or chemically, and in this way probably provided an exit for the first stage larva at hatching. 相似文献
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J. F. Antoniw R. F. White 《European journal of plant pathology / European Foundation for Plant Pathology》1983,89(6):255-264
This review describes the discovery and identification of the pathogenesis-related proteins (PRs) from tobacco. In crude leaf extracts the PRs are distinguished from the proteins in uninfected plants by their solubility at pH 3, resistance to a range of proteases, and mobility in polyacrylamide gels upon electrophoresis (PAGE) in non-denaturing conditions. PAGE has been used as a qualitative and semi-quantitative assay for PRs, and their migration in gels made from different acrylamide concentrations has been used to identify charge and size isomers and electrophoretically identical PRs in different tobacco cultivars. The subunit composition and molecular weight (mol. wt) of the four PRs identified first in Xanthi-nc were determined by SDS-PAGE; staining the gels has shown that these same four proteins in Samsun NN did not contain carbohydrate, lipid or nucleic acid, nor were they isozymic forms of twenty five enzymes known to increase in activity following infection with TMV. Evidence suggests that most of the PRs in Xanthi-nc and Samsun NN are extracellular.The purification of several PRs from Xanthi-nc, Samsun NN and other tobaccos is described, as well as their mol. wt, subunit and amino acid composition. PRs 1a, b and c consist of a single polypeptide and have similar mol. wt and amino acid compositions. Antisera prepared against purified Xanthi-nc b1 protein have been used to determine serological relationships between PRs and form the basis of a very sensitive quantitative assay using ELISA. The regulation of synthesis of some PRs has been shown to involve translational control. 相似文献