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Giuseppina Chianese Ernesto Fattorusso Masteria Yunovilsa Putra Barbara Calcinai Giorgio Bavestrello Aniello Schiano Moriello Luciano De Petrocellis Vincenzo Di Marzo Orazio Taglialatela-Scafati 《Marine drugs》2012,10(11):2435-2447
Leucettamols, bifunctionalized sphingoid-like compounds obtained from a marine sponge Leucetta sp., act as non-electrophilic activators of the TRPA1 channel and potent inhibitors of the icilin-mediated activation of the TRPM8 channel, while they are inactive on CB1, CB2 and TRPV1 receptors. Leucettamols represent the first compounds of marine origin to target TRPA1 and the first class of natural products to inhibit TRPM8 channels. The preparation of a small series of semi-synthetic derivatives revealed interesting details on the structure-activity relationships within this new chemotype of simple acyclic TRP modulators. 相似文献
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Nana S. S. U. Putra Imran Lapong Sugeng Raharjo Navneet K. Dhand 《Journal Of Applied Aquaculture》2013,25(4):293-307
Four selectively bred strains of Nile tilapia (Oreochromis niloticus) were evaluated for production in brackish water ponds in Indonesia. Survival to 124 days was relatively low for all four strains (39%–48%), and growth during the later stages of the trial was poor (SGR < 1.5 %/day) due to water quality deterioration in the pond. Although the ‘Red’ tilapia strain demonstrated the best production parameters, red-colored tilapia bring lower prices in both our test markets (South Sulawesi and Aceh provinces). Of the four strains, the genetically enhanced supermale Indonesian tilapia?×?genetic improvement of farmed tilapia (GESIT×GIFT) cross provided the best economic return. 相似文献
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W. Aimrun M. S. M. Amin Desa Ahmad M. M. Hanafi C. S. Chan 《Paddy and Water Environment》2007,5(2):113-121
On-the-go EC sensor is a useful tool in mapping the apparent soil electrical conductivity (ECa) to identify areas of contrasting soil properties. In non-saline soils, ECa is a substitute measurement for soil texture. It is directly related to both water holding capacity and cation exchange capacity
(CEC), which are key ingredients of productivity. This sensor measures the ECa across a field quickly and gives detailed soil features (1-s interval) with few operators. Hence, a dense sampling is possible
and therefore a high resolution ECa map can be produced. This paper presents experiences in acquiring detailed ECa information that is correlated to other soil properties for precision farming of rice. The study was conducted on a 9 ha
rice plot in MARDI Seberang Prai Station, Penang. The VerisEC3100 was pulled across the field in a series of parallel transects
spaced about 15 m apart. The study showed that shallow and deep ECa had high correlation and shallow ECa had significant correlation to P. Deep ECa had significant correlation to P, K and yield. Regression equations showed that N and P could be estimated by shallow ECa but, pH, K and yield were better estimated by deep ECa. This study was able to draw some basic ideas of nutrient zone management according to precision farming technique. 相似文献
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Joko Tri Wibowo Peni Ahmadi Siti Irma Rahmawati Asep Bayu Masteria Yunovilsa Putra Anake Kijjoa 《Marine drugs》2022,20(1)
Novel secondary metabolites from marine macroorganisms and marine-derived microorganisms have been intensively investigated in the last few decades. Several classes of compounds, especially indole alkaloids, have been a target for evaluating biological and pharmacological activities. As one of the most promising classes of compounds, indole alkaloids possess not only intriguing structural features but also a wide range of biological/pharmacological activities including antimicrobial, anti-inflammatory, anticancer, antidiabetic, and antiparasitic activities. This review reports the indole alkaloids isolated during the period of 2016–2021 and their relevant biological/pharmacological activities. The marine-derived indole alkaloids reported from 2016 to 2021 were collected from various scientific databases. A total of 186 indole alkaloids from various marine organisms including fungi, bacteria, sponges, bryozoans, mangroves, and algae, are described. Despite the described bioactivities, further evaluation including their mechanisms of action and biological targets is needed to determine which of these indole alkaloids are worth studying to obtain lead compounds for the development of new drugs. 相似文献
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On plants at 59 sugarcane plantations in Central and East Java, Indonesia, we found virus-like symptoms such as streak mosaic.
The virus was transmitted mechanically and was sett-borne. The nucleotide sequence of the coat protein gene had the highest
identity with that of Sugarcane streak mosaic virus (SCSMV) isolate Pakistani. We tentatively designate this isolate as SCSMV-Idn (Indonesia). 相似文献
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Large-scale intensification of smallholder cacao management is currently affecting the agroforestry landscapes of Sulawesi (Indonesia), the world’s third largest cacao producer. Little is known about how this shift from diverse plantations to full-sun cacao will affect functionally important biodiversity within the agroecosystem, and how this is related to landscape-wide patterns in land-use and natural ecosystems. We recorded birds in 43 cacao plots differing in woody and herbaceous vegetation as well as distance to forest in two valleys around the Lore Lindu National Park in Central Sulawesi. Species richness of frugivores and nectarivores decreased with increasing distance to forest, whereas granivorous birds increased in richness. Forest specialists, but not habitat generalists, responded positively to forest edge proximity. Species richness of all functional groups except seed eaters increased at higher density of tall shade trees. Greater species richness of shade trees was associated with higher species richness of frugivores and nectarivores, while herbaceous vegetation did not have a strong impact on the avifauna. The positive effect of shade trees was independent of distance to forest. In conclusion, our study shows the relative importance of local and landscape effects on bird diversity with shade trees being critical for bird conservation in cacao agroforestry landscapes. 相似文献
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Bea Maas Dadang Dwi Putra Matthias Waltert Yann Clough Teja Tscharntke Christian H. Schulze 《Biological conservation》2009,142(11):2665-2671
Studies on temporal changes of tropical bird communities in response to habitat modification are rare. We quantified changes in bird assemblages at the rainforest margin of Lore Lindu National Park, Central Sulawesi, over an interval of 6 years. Standardized bird counts were conducted in the years 2001/2002 and 2008 at 15 census points representing natural forest, secondary forest, agroforest and openland sites. Although overall species richness remained nearly identical, different species groups were affected unequally by habitat modification within the forest margin landscape. The mostly endemic forest species declined in abundance (72.0% of forest species) and were detected at fewer census points in 2008 (56.0%). In contrast, 81.8% of the solely widespread openland birds became more abundant and 63.6% of the species were recorded at a larger number of census points. Hence, recent human activities in the forest margin ecotone negatively affected species of high conservation value. Species richness turned out to be a poor indicator of habitat change, and our results underline the importance of considering species identities. Biotic homogenization as result of habitat conversion is a global phenomenon. In our study, the winners were widespread openland species, while the losers were endemic forest birds. In conclusion, our study shows that 6 years of land-use change had negative impacts on bird community structure and endangered species, but not on overall bird species richness. 相似文献
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Agarwood, the resinous product of Aquilaria spp.(Thymelaeaceae), is highly valued for medicinal and fragrant purposes. Unsustainable forest harvesting contributes to the declining population in the wild, threatening their existence. As a protection effort, cultivation occurred in range countries, mainly in Asia, effectively establishing mass plantations. The success of domesticating Aquilaria relies heavily on technological advancement in agarwood induction, without which the entire thriving industry will collapse. In this paper, we describe efforts since 1929 and current progress and variation in induction as practiced in Asia. The methods include traditional practices and artificial induction via inoculum and chemical inducer, experimented and patented or otherwise. Artificial induction methods are being developed to intensify agarwood production in terms of yield and quality. While traditional methods are commonly applied by rural planters, artificial methods with the use of specific agents/chemicals are seen as more appealing for inducing agarwood, and have a higher demand from entrepreneurs and plantation owners.Several issues related to induction technology faced by stakeholders in agarwood cultivation are presented, such as safety levels, cost, yields, and quality. We conclude by highlighting remaining challenges in induction methods and their associated technologies. 相似文献
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Mingzhu Liu Qing Yu Hehe Xiao Yi Yi Hao Cheng Dedi Fazriansyah Putra Yaming Huang Qin Zhang Pengfei Li 《Journal of fish diseases》2020,43(5):531-540
Grouper iridovirus causes high mortality rates in cultured groupers, and effective treatment for grouper iridovirus infection is urgently required. Illicium verum Hook. f. is a well-known medicinal plant with a variety of biological activities. The aim of this study was to analyse the use of I. verum extracts to treat grouper iridovirus infection. The safe working concentration of each I. verum extract was identified both in vitro and in vivo as follows: I. verum aqueous extract (IVAE) ≤ 500 μg/ml; I. verum ethanol extract (IVEE) ≤ 250 μg/ml; shikimic acid (SKA) ≤ 250 μg/ml; trans-anethole (TAT) ≤ 800 μg/ml; 3,4-dihydroxybenzoic acid (DDBA) ≤ 400 μg/ml; and quercetin (QCE) ≤ 50 μg/ml. The inhibitory activity of each I. verum extract against grouper iridovirus infection was analysed using aptamer (Q2)-based fluorescent molecular probe (Q2-AFMP) and RT-qPCR. All of the I. verum extracts displayed dose-dependent antiviral activities against grouper iridovirus. Based on the achieved per cent inhibition, IVAE, IVEE, DDBA and QCE were associated with the greatest antiviral activity (all > 90%). Together, our results indicate that I. verum extracts have effective antiviral properties, making it an excellent potential source material for the development of effective treatment for grouper iridovirus infection. 相似文献