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排序方式: 共有141条查询结果,搜索用时 15 毫秒
1.
Donald E. Thrall DVM PHD Margaret C. McEntee DVM† Carol Novotney DVM† Marlene L. Hauck DVM† Rodney L. Page DVM MS† 《Veterinary radiology & ultrasound》1993,34(4):295-300
Eighteen dogs with malignant nasal cavity tumors were treated with radiation therapy, including a boost technique. Three 3:0 Gy boost doses were added to a treatment protocol consisting of sixteen 3.0 Gy daily fractions, bringing the total dose to 57 Gy. This boost technique was implemented without an associated increase in overall treatment time by giving the boost doses on a twice-a-day basis. Boost doses were given during the first half of the radiation therapy period. The treatment was completed as planned in 16 of the 18 dogs; two dogs received lower doses (51 and 54 Gy). Median survival was 177 days, poorer than in some other reported studies of nasal tumor irradiation. Acute effects were unacceptable, with 11 of the 18 dogs developing severe mucositis, desquamation, edema, swelling, and pruritus. The extensive nature of the acute reactions compromised assessment of the effect of the increased radiation dose on the tumor. Although there is justification for assessing more aggressive radiation protocols in canine nasal tumor patients, total doses approximating 60 Gy can not be given as described because of the inability of acutely responding normal tissues to compensate. 相似文献
2.
Marlene Cordero Pedro L. Ramos Lester Hernández Ana I. Fernández Ana L. Echemendía Rudy Peral Gloria González Daniel García Surey Valdés Ana Estévez Keren Hernández 《Phytoparasitica》2003,31(5):478-489
The presence of a begomovirus in potato plants with yellow mottle symptoms was determined for the first time in Cuba. The
incidence of typical begomovirus-like symptoms in potato plants in some regions of Havana province (Güira de Melena, San José
de las Lajas, Güines and Boyeros) during the growing seasons from 1992 to 1998 was in general low. However, in some cultivars
belonging to the National Program for Potato Genetic Improvement, the incidence reached 100%. Yield losses, determined in
1992 and 1994, ranged as high as 19% to 56.33% depending on the cultivar. Characterization of the causal agent was done by
light microscopy, host range (graft and mechanical transmission), DNA hybridizations, polymerase chain reaction, and restriction
fragment length polymorphism analysis. Nucleotide sequence of the amplified fragments revealed the presence ofTomato mottle Taino virus. The virus was transmittedvia tubers and has been detected in mixed infections withPotato virus X and withPotato leaf roll virus.
http://www.phytoparasitica.org posting Oct. 20, 2003. The first two authors contributed equally to this work. 相似文献
3.
Svenja Hartung Elfi K. Schlohsarczyk Alexandra Jost Marlene Sickinger Kernt Khler 《Journal of veterinary diagnostic investigation》2022,34(2):298
In human and veterinary medicine, mixed Müllerian tumors (MMTs) are rarely diagnosed neoplasms of the tubular female genital tract. Although there are case reports of malignant MMTs in various species, benign MMTs have only been described once in a macaque. Here we present a case of benign MMT in a 12-y-old goat, and review the literature on uterine, cervical, and vaginal neoplasia in goats. The doe was presented with vaginal discharge and was euthanized because of the high suspicion of intraabdominal neoplasia. On gross examination, an ulcerated vaginal mass was identified. Histologically, 2 distinct cell populations were present: smooth muscle cells that were well differentiated and positive for alpha–smooth muscle actin, and ciliated columnar epithelial cells that lined ductal structures and had no signs of malignancy. These findings led to the diagnosis of neoplasia of Müllerian origin. Benign MMT should be considered as a differential diagnosis for uterine and vaginal neoplasms in goats. 相似文献
4.
Soriano VE Blackall PJ Dabo SM Téllez G García-Delgado GA Fernández RP 《Avian diseases》2001,45(3):680-683
A total of 42 isolates of Haemophilus paragallinarum from Mexico were serotyped by the Kume hemagglutinin scheme. Serovars A-1, A-2, B-1, and C-2 were recognized among 11 (26.2%), 7 (16.6%), 4 (9.5%), and 14 (33.3%) isolates, respectively. A further six isolates (14.3%) showed hemagglutinating activity but could not be classified into any serovar. Commercial vaccines containing Kume serovars A-1, A-2, B-1, and C-2 may provide better protection than those bi- or trivalent infectious coryza vaccines currently used in Mexico. 相似文献
5.
David R. Proulx DVM David M. Ruslander DVM Richard K. Dodge MS Marlene L. Hauck DVM PHD Laurel E. Williams DVM Birgitte Horn BVSc G. Sylvester Price DVM PHD Donald E. Thrall DVM PHD 《Veterinary radiology & ultrasound》2003,44(3):352-359
Despite the early notion that canine oral malignant melanoma is radioresistant, recent data suggest that external beam radiotherapy is effective in local tumor control. However, optimal fractionation schedules have not been established. The high rate of regional and distant metastasis is another problem that has hindered long-term control. The role of chemotherapy in the management of canine oral melanoma has also not been determined. In this study, data from 140 dogs irradiated at North Carolina State University were evaluated with the following objectives: (1) to compare the efficacy of three radiation therapy protocols (36 Gy, 9 Gy x 4 fractions; 30 Gy, 10 Gy x 3 fractions; or >45 Gy, 2-4 Gy x 12-19 fractions) for the treatment of dogs with oral malignant melanoma, (2) to identify any host or tumor factors influencing prognosis, and (3) to determine the impact of systemic chemotherapy on treatment outcome. Information regarding response to therapy, disease progression, and survival were determined from the medical records or from information obtained by telephone or mail survey. Relationships between host, tumor, and treatment variables and outcome measures (response, time to first event, and survival) were evaluated using Fisher's exact test (response) and the Cox regression model (time to first event and survival). The median time to first event for the 140 dogs was 5.0 months (95% C.I., 4-6 months) and the median survival was 7.0 months (95% C.I., 6-9 months). In the univariate analysis, the following variables were associated with increased time to first event and survival: (1) rostral tumor sublocation; (2) lack of bone lysis observed on skull imaging, and (3) microscopic tumor burden. In a multivariate analysis of 111 dogs with complete data for these variables, tumor sublocation, bone lysis, and tumor volume were identified as joint predictors of time to first event (p < .001, p < .001, and p = .04, respectively) and survival (p < .001, p < .001, and p = .05, respectively). There were no differences in response, time to first event and survival between the three radiation therapy protocols used. Systemic chemotherapy had no impact on the development of metastatic disease, time to first event, or survival, although the dosages used in this study were suboptimal. External beam radiation therapy is effective in local disease control of canine oral malignant melanoma; however, the optimal fractionation scheme has yet to be determined. The high metastatic rate observed with this disease and the inefficacy of systemic chemotherapy indicate that further investigation into novel therapies is warranted. 相似文献
6.
Marlene Hauck 《Veterinary Clinics of North America: Small Animal Practice》2003,33(3):553-7, vii
Injection site sarcomas in cats have been the topic of more than 40 articles and over 20 scientific abstracts as well as multiple letters to veterinary journals, articles in the popular press, and Internet-based web sites. With the level of discussion that has surrounded this tumor entity, one might expect that great strides have been made in determining the etiology, epidemiology, and preferred treatment options for this disease. Nearly half of the publications on this subject are review articles, however, and that alone indicates both the high level of interest and the lack of information in this situation. This article summarizes the development of our current understanding of this tumor with regard to areas of research into the cause of injection site sarcomas, epidemiology, and the current standard of care for treatment of this iatrogenic disease. 相似文献
7.
8.
Jose A Morales Ligbel Sanchez Harvi Velasquez Beatriz De Borrego Marlene De Nava Denis Portillo Yulixis Cano Angel Morillo Ana Albornoz Elsa Socorro 《Water, air, and soil pollution》2001,130(1-4):511-516
Nutrient content and pH of rain samples collected at nine sites during 1988-1996 were studied to determine the amounts of N, P and S added by precipitation over Maracaibo Lake basin. The basin is a wide depression occupied by Lake Maracaibo and extensive alluvial plains and delimited by a mountainous zone of variable physiolgraphic characteristics with different cattle ranching and industrial activities. Rain pHs averaged ≈ 4 to 6, individual samples occasionally reached as low as pH 3 in the south basin. NH4 + levels were significantly higher (up to 2.6 mg/l NH4-N) than NO3 ? plus NO2 ?. Phosphorus levels were low, ranging from undetectable to 1.5 mg/l. The amounts of inorganic N/ha/yr added ranged from ≈ 5.4 Kg in the north to ≈ 8 Kg in the south basin; around the lakeshore, it was estimated that ≈ 9.8–16.8 Kg TN/ha (≈ 55 % as organic-N) are annually deposited. The annual amounts of SO4-S/ha added range from ≈ 10 to 13 Kg. The contribution of precipitation to P in the ecosystem is very small; ≈ 0.02 – 0.8 Kg of PO4-P/ha/yr was added in basin. The results of this study show that precipitation represents a significant factor for the total nitrogen and sulfur loading to Maracaibo Lake Basin. 相似文献
9.
Soil properties in organic olive groves compared with that in natural areas in a mountainous landscape in southern Spain 总被引:1,自引:0,他引:1
This study evaluates soil properties in organically managed olive groves and natural zones in a mountainous area of Andalusia, Spain. Two soil types (Eutric Regosol and Eutric Cambisol) and the most common soil management methods (tillage and two intensities of grazing) were studied. Both soil types in the groves had values not much lower than those in the natural areas. Average (±SE) values in the groves were 1.58 ± 0.71% for organic carbon, 323 ± 98 g kg?1 for macroaggregate stability, 1.11 ± 0.16 g cm?3 for bulk density, 3.5 ± 1.6 mm h?1 for saturated hydraulic conductivity and 1209 ± 716 mg CO2 kg?1 for soil respiration. Overall, these values tended to be lower in the tilled compared with that in the grazed groves. The average phosphorus soil content (5.83 ± 5.22 mg kg?1) was low for olive production and within adequate ranges for N (0.12 ± 0.05%) and K (142 ± 81 mg kg?1). Soil erosion was high in the tilled groves (35.5 ± 18.2 t ha?1 year?1) with soil loss correlating with indicators of soil degradation such as organic carbon content and water stable macroaggregates. In the grazed groves, soil loss was moderate with no clear indications of soil degradation. Overall, there was significant farm‐to‐farm variability within the same soil and land management systems. Olive production had a moderate effect on soil degradation compared with natural areas and olive cultivation could be sustained in future if cover crop soil management replaced tillage, especially in the most sloping areas. 相似文献
10.
Nadeau JH Balling R Barsh G Beier D Brown SD Bucan M Camper S Carlson G Copeland N Eppig J Fletcher C Frankel WN Ganten D Goldowitz D Goodnow C Guenet JL Hicks G Hrabe de Angelis M Jackson I Jacob HJ Jenkins N Johnson D Justice M Kay S Kingsley D Lehrach H Magnuson T Meisler M Poustka A Rinchik EM Rossant J Russell LB Schimenti J Shiroishi T Skarnes WC Soriano P Stanford W Takahashi JS Wurst W Zimmer A;International Mouse Mutagenesis Consortium 《Science (New York, N.Y.)》2001,291(5507):1251-1255