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1.
Five horses with a primary surgical lesion of the small (descending) colon were diagnosed with eosinophilic colitis based on visual and histopathological examination. These were evident as visibly striking, hyperaemic, focal lesions of the small colon, with serosal petechiation, oedema and marked thickening of the intestinal wall at the site. Areas of focal necrosis were also evident. The gross appearance of the lesions were considered to be sufficiently severe in all cases to merit resection, due to concerns about intestinal necrosis and septic peritonitis. An inability to fully exteriorise the affected portion of intestine to perform a resection and anastomosis necessitated intraoperative euthanasia of one horse. A total of three horses survived to hospital discharge. Eosinophilic colitis lesions are a rare cause of severe small colon disease, but should be considered in cases with similar visual characteristics. 相似文献
2.
Failure of a recombinant Schistosoma bovis-derived glutathione S-transferase to protect cattle against experimental Fasciola hepatica infection 总被引:2,自引:0,他引:2
De Bont J Claerebout E Riveau G Schacht AM Smets K Conder G Brake DA Capron A Vercruysse J 《Veterinary parasitology》2003,113(2):135-144
The potential of a recombinant Schistosoma bovis 28-kDa glutathione S-transferase (rSb28GST) to protect cattle against Fasciola hepatica was tested in a vaccination trial. Thirty two calves were randomly divided into four groups of eight animals. Calves of the three vaccine groups received two intramuscular injections at 3 weeks interval, of 0.250mg rSb28GST in either aluminium hydroxide (Al(OH)(3)), Quil A, or PBS emulsified in an equal volume of Freund's complete adjuvant (FCA).Animals of the control group received injections of Al(OH)(3)/PBS only. All animals were challenged orally with a total of 360 metacercariae of F. hepatica, spread over 6 weeks.All groups of vaccinated animals produced measurable IgG antibody titers to rSb28GST after vaccination. Animals immunised with FCA adjuvanted vaccine had the highest and more durable antibody titers and only sera from this group recognised an approximately 24kDa protein band from F. hepatica, that is thought to be a F. hepatica GST. Despite a good antibody response differences in cumulative faecal egg output between the groups were not statistically significant. In addition, no significant difference was found between groups in terms of total worm numbers or percentage of immature flukes recovered at necropsy. In conclusion, the recombinant S. bovis 28kDa GST was not found to adequately protect cattle against experimental F. hepatica challenge, using either aluminium hydroxide, Quil A or FCA as adjuvant. 相似文献
3.
The persistent efficacy of four commercially available macrocyclic lactones (ML) in maintaining reduced faecal egg counts in cattle grazing naturally infested pastures was evaluated in 44 zebu animals aged 1–2 years in Zambia. The study started in February (rainy season) when the strongyle egg output was increasing. Four days before the start of the trial, all animals were treated with a double dose of oxfendazole. They were then divided into five groups which were again treated on day 0. Groups A, D, I and M received 0.2 mg kg−1 of abamectin, doramectin, ivermectin and moxidectin, respectively. Animals of group C received albendazole (7.5 mg kg−1). Faecal samples were collected twice a week for egg counts and larval differentiation. Faecal egg counts in the C group increased from day 21 onwards and plateaued from day 42 between 180 and 380 eggs per gram. The main genera found in cultures were Cooperia (90%) and Haemonchus (7%). Faecal egg excretion in groups M, A, D and I started on day 35, 42, 42 and 45, respectively. subsequently and until day 84, average counts in these four groups were always significantly lower than in group C. Compared with albendazole, all four ML gave over 95% reduction in cumulative faecal egg counts for 42 days after treatment. The percentage efficacy was still over 84% by day 84 when an average cumulative egg count of 11 320 eggs per gram faeces was calculated in group C. In addition, there was no significant difference in efficacy between the four ML groups at any of the sampling dates. During the trial no significant difference in weight gain between any of the groups was observed. 相似文献
4.
Lipomatosis is an uncommon cause of colic. This case report details the pre‐ and intraoperative findings of a 9‐year‐old gelding, presented with acute abdominal pain. Exploratory laparotomy revealed a massive fatty infiltrate involving an extensive portion of the base and mid‐body of the caecum. To the authors' knowledge, this is the first report of an infiltrative lipomatous lesion of the equine caecum. 相似文献
5.
F. C. F. Worsman S. Z. Barakzai M. P. de Bont S. Turner L. M. Rubio-Martínez 《Equine Veterinary Education》2020,32(2):71-77
This report describes two cases of successful surgical management of granulosa cell tumours (GCT) in mares presenting with haemoperitoneum (HP). Controlled abdominal drainage was initially attempted in Case 1 but was not successful. A ventral midline exploratory laparotomy allowed removal of a haemorrhaging 13 kg GCT. The mare made a full recovery and returned to normal work as a driving pony 11 months post-operatively. In Case 2 controlled abdominal drainage was followed by standing left flank laparoscopic visualisation of the bleeding ovary and transection of the ovarian pedicle by electrocautery. The GCT was then removed via a ventral midline incision due to its large size. Haemoperitoneum can be associated with GCTs and in some cases is severe enough to prompt emergency treatment. Stabilisation of the patient and removal of the haemorrhaging GCT can lead to a successful outcome. 相似文献
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7.
Cable-based technologies have been a backbone for harvesting on steep slopes. The layout of a single cable road is challenging because one must identify intermediate support locations and heights that guarantee structural safety and operational efficiency while minimizing set-up and dismantling costs. Our study objectives were to (1) develop an optimization approach for designing the best possible intermediate support layout for a given ground profile, (2) compare optimization procedures between linearized and nonlinear analyses of a cable structure and (3) investigate the effect of simplifying a multi-span representation. Our results demonstrate that the computational effort is 30–60 times greater for an optimization approach based on nonlinear cable mechanical assumptions than when considering linear assumptions. Those nonlinear assumptions also stipulate lower heights for intermediate supports and a larger span length. Finally, compared with the unloaded case, tensile force in the skyline is increased by as much as 80% under load for a single-span skyline configuration. Our approach provides additional value for cable operations because it ensures greater structural safety at a lower cost for installation. Improvements are still needed in developing a stand-alone application that can be easily distributed. Moreover, our rather simple assumptions regarding set-up and dismantling costs must be refined. 相似文献
8.
Emulsion properties of casein and whey protein hydrolysates and the relation with other hydrolysate characteristics 总被引:5,自引:0,他引:5
van der Ven C Gruppen H de Bont DB Voragen AG 《Journal of agricultural and food chemistry》2001,49(10):5005-5012
Casein and whey protein were hydrolyzed using 11 different commercially available enzyme preparations. Emulsion-forming ability and emulsion stability of the digests were measured as well as biochemical properties with the objective to study the relations between hydrolysate characteristics and emulsion properties. All whey protein hydrolysates formed emulsions with bimodal droplet size distributions, signifying poor emulsion-forming ability. Emulsion-forming ability of some casein hydrolysates was comparable to that of intact casein. Emulsion instability was caused by creaming and coalescence. Creaming occurred mainly in whey hydrolysate emulsions and in casein hydrolysate emulsions containing large emulsion droplets. Coalescence was dominant in casein emulsions with a broad particle size distribution. Emulsion instability due to coalescence was related to apparent molecular weight distribution of hydrolysates; a relative high amount of peptides larger than 2 kDa positively influences emulsion stability. 相似文献
9.
Fatima Tamtam Barbara Le Bot Tuc Dinh Sophie Mompelat Joelle Eurin Marc Chevreuil Philippe Bonté Jean-Marie Mouchel Sophie Ayrault 《Journal of Soils and Sediments》2011,11(5):852-859
Purpose
Even though sediments may represent a reservoir for antimicrobial agents, little is known about the persistence of these molecules over time or their accumulation. In this study, six antimicrobial agents, oxolinic acid, flumequine, nalidixic acid, norfloxacin, sulphamethoxazole and trimethoprim, were investigated in a sediment core from the Seine River. This work aimed to (1) measure antimicrobial agent contamination levels in the sediment and identify their origins, (2) obtain information on the persistence of these compounds in sediment over long periods (>4 years) and (3) show the existence of a historical record in sediment of river contamination by antimicrobial agents. 相似文献10.
Oldrich Navratil Olivier Evrard Michel Esteves Sophie Ayrault Irène Lefèvre Cédric Legout Jean-Louis Reyss Nicolas Gratiot Julien Nemery Nicolle Mathys Alain Poirel Philippe Bonté 《Journal of Soils and Sediments》2012,12(9):1463-1478