Postoperative glaucoma in the Labrador Retriever: incidence, risk factors, and visual outcome following routine phacoemulsification

Objective To evaluate the incidence and risk factors associated with development of postoperative glaucoma in the Labrador Retriever following routine phacoemulsification. Methods Medical records from Labradors and a randomly selected population of non‐Labradors were retrospectively evaluated. Signalment, diabetic status, cataract stage, gonioscopic findings, presence of preoperative lens‐induced uveitis, development of postoperative hypertension (POH), postoperative glaucoma and postoperative visual status were recorded for each patient. Survival curves were developed using the Cox proportional hazards model. Results Forty‐two Labradors (66 eyes) and 199 non‐Labradors (314 eyes) were included. The incidence of POH was significantly higher in Labradors (33%) than non‐Labradors (18%). Labradors were at significantly increased risk of postoperative glaucoma and blindness compared to non‐Labradors. Estimated probabilities of postoperative glaucoma in Labradors were 23%, 25%, 30% and 35% at weeks 4, 26, 52 and 104, respectively, compared with 5%, 6%, 7% and 9% at weeks 4, 26, 52 and 104, respectively, in non‐Labradors. Estimated probabilities of postoperative blindness in Labradors were 5%, 9%, 15% and 27% at weeks 4, 26, 52 and 104, respectively, compared with 2%, 3%, 5% and 10% at weeks 4, 26, 52 and 104, respectively, in non‐Labradors. Risk factors for the development of glaucoma in Labradors included increasing age and development of POH. No statistically significant risk factors for the development of glaucoma were identified in non‐Labradors. Conclusions Labradors are at increased risk of glaucoma and blindness following phacoemulsification compared with non‐Labradors. POH and increasing age represent risk factors for the development of postoperative glaucoma in Labradors.     

萘乙酸纳米悬浮剂的制备及对苜蓿种苗生长的影响

对萘乙酸(NAA)粉剂采用微乳液-超声乳化法处理,制备萘乙酸纳米悬浮剂,并初步探索了该制剂对苜蓿种苗生长的影响。结果表明:通过微乳液-超声乳化法制备的萘乙酸纳米悬浮剂,其颗粒度小,粒径分布均匀、水溶性好、稳定性好。2.2×10-5mol·L-1萘乙酸纳米悬浮剂的促长效果最好,2.2×10-4mol·L-1悬浮剂的抑制作用最明显。     

Shope fibroma virus keratitis and spontaneous cataracts in a domestic rabbit

A 7-year-old domestic rabbit presented for an enlarging ventral perilimbal mass OS. Keratectomy was performed to remove the mass. A diagnosis of Shope fibroma virus keratitis was confirmed based on signalment, clinical signs, histologic evaluation and virus isolation. Progression of bilateral cataracts leading to visual deficits was addressed with phacoemulsification. The rabbit remained visual and comfortable 5 months postoperatively and free of recurrence of the limbal mass 9 months after initial presentation.     

Phacoemulsification and +14 diopter intraocular lens placement in a Saddlebred foal

A 2‐month‐old, 110‐kg Saddlebred filly presented for evaluation of bilateral cataracts. A hypermature cataract in the left eye (OS) and an incipient nuclear cataract in the right eye (OD) were diagnosed. Electroretinography and ocular ultrasound revealed no contraindications for surgical removal of the cataractous lens OS. Phacoemulsification and implantation of a +14 diopter (D) intraocular lens (IOL) OS were performed at 4 months of age without complication, with the exception of a partial iridectomy performed on a small iris section that prolapsed through the corneal incision. Complete ophthalmic examinations, including ocular ultrasound and streak retinoscopy, were performed 1, 2, 6 weeks, 4 months, 1, and 2 years postoperatively. Diffuse corneal edema and a superficial corneal ulcer developed OS during the early postoperative period and resolved without complication. Dyscoria was identified owing to anterior synechia of the dorsomedial iris at the incision site. Two years after surgery, menace response, palpebral reflex, dazzle reflex, and pupillary light reflexes were present in both eyes (OU). The IOL remained centrally positioned within the capsule, with mild anterior tilting of the superior portion of the IOL and mild fibrosis of the lens capsule. The postoperative net refractive error was +0.31 D OS. Based on this report, a +14 D IOL may be the appropriate choice following lens extraction in a foal to achieve refraction near emmetropia at maturity. To our knowledge, this is the first report of phacoemulsification and IOL implantation in a foal with long‐term follow‐up.