构建基于24XX系列存储器通用函数库的研究

24XX系列EEPROM存储器是目前电子产品开发中使用频率较高的存储设备,文章通过构建基于该存储器的驱动函数和应用函数库,既可以提高产品开发速度,又可以提升存储器的读写稳定性。     

孝感米酒对小鼠记忆力及抗氧化作用的影响

研究孝感米酒对小鼠记忆力及抗氧化作用的影响。D-半乳糖造小鼠衰老模型,分别灌胃高、中、低浓度孝感米酒,30d后一次性被动回避反应试验检测各试验组小鼠行为学变化,并进行脑、血液、肝脏超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量检测。结果表明,各浓度组小鼠反应时间都明显减少(P<0.01),其中,低浓度组小鼠学习成绩显著提高,潜伏期显著延长;脑、红细胞和肝脏SOD活性显著提高(P<0.01),明显降低了脑、血清及肝脏MDA含量(P<0.01)。     

共享内存在铁路电力监控系统中的应用

在Unix下,目前有两种主流共享内存机制,一种是Posix共享内存机制,另一种是System V共享内存机制.本文阐述了这两种共享内存机制的实际实现方法,比较了他们之间的特点与不同.并结合在铁路电力监控系统中的应用,阐述了Posix共享内存机制是如何实现监控系统中的自适应共享内存机制的.     

集配货一体化VRP问题的具记忆功能的模拟退火算法研究

针对集配货一体化车辆路径问题的特性,建立了考虑配送车辆出行固定成本、车辆出发满载系数等因素的更加符合实际的数学模型;并设计了一种带记忆功能的模拟退火算法求解模型,确保输出结果是每次寻优的最优解;最后通过算例计算,结果表明,算法求解更优,稳定性更好,计算效率也较高。     

DOS和WINDOWS环境下的内存管理

本文介绍了微机在ＤＯＳ和ＷＩＮＤＯＷＳ环境下的空间分布及内存管理，并给出了在该环境下有效利用内存的方法     

Intervention of hydrogen on memory damage induced by chronic hypoxia-hypercapnia in rats

AIM: To investigate the effects of hydrogen on the memory damage caused by chronic hypoxia-hypercapnia in rats. METHODS: Twenty-four SD rats trained by eight-arm radial maze test were randomly divided into 3 groups:normal control group (NC), hypoxia-hypercapnia+saline group (MS) and hypoxia-hypercapnia+ hydrogen group (MH). The rats in the latter 2 groups were placed in a closed cabin for 8 h/day,6 days/week and lasted for 4 weeks, in which O₂ was 9％-11％ and CO₂ was 5％-6％. In every time after the animals were out of the cabin, the MS rats were intraperitoneally injected with saline (5 mL/kg) and the MH rats were intraperitoneally injected with hydrogen solution at the same dose. The learning and memory function, the activity of superoxide dismutase (SOD), the content of malondialdehyde (MDA) and 8-hydroxydeoxyguanosine (8-OHdG) were examined after the cabin training. The ultramicrostructures of hippocampus were also observed. RESULTS: (1) Compared with NC group, the number of working memory errors, the total errors, the content of hippocampus 8-OHdG and serum MDA in MS and MH groups were higher and the activity of serum SOD was lower (P<0.05). The hippocampus structure was destroyed and some degree of edema and more apoptosis in the neurons were obserued in MS group and MH group. (2) Compared with MS group, the number of working memory errors(WME), the total errors, the content of hippocampus 8-OHdG and serum MDA were lower and the activity of serum SOD was higher in MH group (P<0.05). In MH group, the morphology of hippocampus structures kept nearly normal arrangement and the only mild edema and fewer apoptosis in the neurons were found. CONCLUSION: Hydrogen may attenuate chronic hypoxia-hypercapnia-induced memory damage in rats by inhibiting apoptosis of the neurons and decreasing detrimental free radicals reaction.     

鸡舍多功能程序控制仪的研制

介绍适用于鸡舍光、声刺激程序控制仪的结构、工作原理、特点以及初步试验结果。     

金针菇多糖改善小鼠学习记忆功能

研究金针菇多糖对正常小鼠学习记忆的影响。利用三等分辐射式迷宫箱训练小鼠,检测每实验日正确反应率、达标小鼠的比率及达标所需训练次数,训练结束后取脑,用紫外分光光度计检测各项指标的OD值,测得超氧化物歧化酶（SOD）和丙二醛（MDA）含量。结果显示低剂量金针菇多糖可显著提高小鼠的达标率,显著降低小鼠达标的训练次数,金针菇多糖对SOD含量水平均有显著的提高作用（p〈0.05）,低剂量的金针菇多糖明显提高大脑海马组织中蛋白质的含量（p〈0.05）并能显著降低MDA含量（p〈0.05）。这表明金针菇多糖对小鼠的学习记忆有一定的促进作用,并能显著提高大脑海马组织中的蛋白质含量,提高SOD活力,降低MDA含量,表现出明显的抗氧化作用。     

Effect of vitamin C on expansion of CD4+ effector memory T cells in vitro

AIM：To investigate the effect of vitamin C (VC), a small-molecule compound, on the expansion of CD4+ effector memory T cells (TEM) in vitro and to improve the effect of adoptive immunotherapy. METHODS：Normal human peripheral blood CD4+ T-lymphocytes were isolated and randomly divided into 2 groups: control group and experiment group. VC was added into experimental group. Thereafter, the expansion of CD4+ TEM in the 2 groups was detected by cell counter and flow cytometry. RESULTS：VC did not significantly affect the total number of CD4+ T cells, while it raised the ratio of TEM in CD4+ T cells at an optimal concentration of 100 mg/L. After 10 days of the expansion of CD4+ T cells, the number of CD4+ TEM in experiment group was (3.56±0.35)×106, significantly larger than that in control group ［(1.22±0.15)×106, P<0.01］. CONCLUSION: VC can effectively promote the expansion of CD4+ TEM in vitro, which provides a simple, safe and effective expansion method for adoptive immunotherapy.     

某弦支穹顶屋盖地震响应的三维隔震控制

以潍坊鸢都体育馆屋盖为弦支穹顶结构的工程背景,分别采用研发的SRB和PCDSB作为屋盖的水平向和竖向隔震设备,以此设计了屋盖的S-P三维隔震层,利用子空间迭代法对隔震屋盖进行了动力特性分析,运用Newmark逐步积分法和四阶显式Runge-Kutta迭代法编制了求解隔震屋盖地震响应的非线性时程分析程序X,采用ABAQUS有限元软件验证了自编程序X的正确性,并利用程序X对Ⅷ度和Ⅸ度地震波作用下的未隔震和隔震屋盖的地震响应进行了对比分析.结果表明：隔震屋盖的前四阶振型表现为水平向和竖向振动相耦联的特点;相同烈度同条地震波作用下,隔震屋盖的地震响应较未隔震的有了明显降低;同条地震波作用下,Ⅸ度的隔震屋盖地震响应比Ⅷ度的要大;本文设计的隔震屋盖在低频脉冲型地震波作用下,仍能保持较低的地震响应.