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91.
目的通过对奥唑嗪(AZQ)口服液初步的药理学实验观察,确定其对支气管哮喘的治疗作用.方法采用药理学实验方法,将200只小鼠随机分成4组,每组50只,各组分别设置中药奥唑嗪大剂量组(200mg/kg)、中剂量组(100mg/kg)、小剂量组(50ms/kg)3个剂量组、阳性对照组(抗炎为醋酸可的松;止咳为蛇胆川贝液;祛痰为氯化铵;平喘为氨茶碱)及生理盐水对照组,分别对其进行抗炎、止咳、祛痰、平喘等药效学观察.结果奥唑嗪口服液100mg/kg和50mg/kg剂量组对抗炎有一定作用;50mg/kg剂量组对止咳有显著作用;70mg/kg和100mg/kg剂量组对祛痰有显著疗效;100mg/kg和50mg/kg剂量组对平喘有明显作用.结论奥唑嗪口服液对抗炎、止咳、祛痰、平喘有一定疗效,可以开发研制为二类新药. 相似文献
92.
动物黏膜免疫细胞研究进展 总被引:7,自引:0,他引:7
动物机体内存在着强大的黏膜免疫系统,约占机体淋巴组织的50%以上。黏膜免疫系统具有大量的免疫细胞,它们弥散分布在黏膜上皮内及黏膜下,或由单个或多个淋巴滤泡聚集成淋巴小结,大量的黏膜免疫细胞摄取、呈递抗原,诱导发生免疫反应,产生免疫效应因子(主要为SIgA),发挥免疫作用,抵抗病原菌对机体的侵袭。 相似文献
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应用透射电镜技术,对15只正常中华鳖小肠和大肠黏膜上皮细胞的超微结构进行了研究。结果表明,中华鳖小肠黏膜上皮为单层柱状上皮,以高柱状吸收细胞为主,具有发达的微绒毛、线粒体、粗面内质网和膜包小囊泡,其结构的发达程度已接近高等哺乳动物和鸟类。吸收细胞之间可见少量低电子密度的亮细胞,其种类需进一步确定。杯状细胞明显可见,胞质内含大量黏液性颗粒,细胞游离面形成明显的微绒毛。内分泌细胞很少。大肠黏膜上皮细胞排列松散,全部由上下粗细不均的柱状细胞组成。大肠上皮内未见专门的杯状细胞,但上皮细胞顶部胞质内含大量黏液颗粒,细胞器分布于黏液颗粒团之下的胞质中。细胞间隙宽大明显,有利于黏膜免疫细胞出入上皮。小肠和大肠均未见腺体分布。 相似文献
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马克思"人的全面而自由发展"思想是新时期新阶段我国社会文明建设的指针,是我们正确认识社会主义初级阶段本质特征的理论依据.他肯定了物质生产力对实现人的全面而自由发展的重要意义,为推动我国社会主义现代化建设和实现人的全面发展指出了方向. 相似文献
98.
Á. Jerzsele Z. Karancsi E. Pászti‐Gere Á. Sterczer A. Bersényi K. Fodor D. Szabó P. Vajdovich 《Journal of veterinary pharmacology and therapeutics》2018,41(3):409-414
Xylitol is commonly used as sugar substitute in households. While it has numerous beneficial effects on human health, it is highly toxic to dogs. The goal of this study was to examine whether xylitol has similar deleterious effects, such as hypoglycaemia and acute hepatic failure, on cats. Our research included six healthy middle‐aged cats. Xylitol was dissolved in deionized water and administered p.o. at three doses (100, 500 and 1,000 mg/kg body weight). These dosages have been considered toxic and can cause liver failure or even death in dogs. After every xylitol administration, the basic health status and the blood glucose of cats were observed regularly. Additionally, prior to and 6, 24 and 72 hr after xylitol administration, blood samples were taken to check complete blood count, clinical biochemical parameters and enzymes such as ALT, ALKP, GGT, GLDH, bile acids, BUN, creatinine, phosphate, total protein, albumin, sodium and potassium. There were no significant changes (p > .05) in any of the haematological or biochemical parameters. Blood glucose concentrations did not show any significant alterations, except at 1,000 mg/kg dose, where a mild but significant increase was observed, but it was in physiological range. Based on our results, xylitol did not induce toxic effects on cats. 相似文献
99.
J. P. Rodríguez M. Aro M. Coarite S.‐E. Jacobsen B. Ørting M. Sørensen C. Andreasen 《Journal of Agronomy and Crop Science》2017,203(3):254-267
Cañahua (Chenopodium pallidicaule Aellen) is a semi‐domesticated relative of quinoa (Chenopodium quinoa Willd.) with high nutritious quality. It is tolerant to frost, drought, saline soils and pests. One seed yield limitation is seed loss during the maturity stages. Two greenhouse experiments in Denmark and field experiments in Bolivia were carried out to determine seed shattering in landraces and cultivars with different growth habits. 15–21 % of the seed shattering in the fields took place whilst the plants still were flowering and 25–35 % during physiological maturity. Seed shattering varied between locations on the Bolivian Altiplano. Cañahua types with the semi‐prostrate growth (‘lasta’) had the highest seed shattering rate in the greenhouse experiments. The Umacutama landrace had lower seed shattering (1 %) than the cultivar Kullaca (7.2 %) both of the ‘lasta’ type. Under field conditions, the cultivar Illimani with the erect growth (‘saihua’) had the highest seed shattering rate (6.4–33.7 %) at both locations and at four different sowing dates. The Umacutama had the lowest rate (0.5–1.5 %). There were no significant differences between plants of the ‘lasta’ and the ‘saihua’ types. The landrace had significantly less seed loss than the cultivars. However, in the greenhouse, the landrace yield was approximately 25 % lower than the yields of the cultivars. In general, cañahua cultivars had higher yield compared to landraces, but also a higher seed shattering rate. Landraces may be used in breeding programmes to develop high‐yielding cultivars with reduced seed shattering. 相似文献
100.
《Communications in Soil Science and Plant Analysis》2012,43(5):461-473
Abstract Extracts that are coloured, owing to dissolved organic matter, give rise to an interference when boron is determined by the colorimetric Azomethine‐H method. A scheme is presented in which boron is removed from coloured extracts by dialysis. In this way the interference can be removed automatically. The suggested scheme allows hydroponic solutions and extracts of soils, peat‐based composts and plant materials to be analysed without further treatment at a rate of 20 hr‐1. The limit of detection is 0.05ppm B in solution. Recoveries of boron added to extracts from all types of sample were excellent. The effects of some interferences were investigated and found not to be significant under normal working. 相似文献