Caprine besnoitiosis: an emerging threat and its relationship to some other infections of ungulates by Besnoitia species

Caprine besnoitiosis, caused by the cyst-forming protozoal apicomplexan Besnoitia caprae appears to be endemic in Kenya, Nigeria and Iran, but has yet to be detected in other parts of the world. The infection causes an important parasitic disease of goats in affected developing countries. Bovine besnoitiosis, is a widespread disease of cattle in Africa, Asia (but not Iran) and southern Europe. Recent epidemiological data confirm that the incidence and geographical range of bovine besnoitiosis in Europe is increasing, which is why growing attention has been given to the condition during the past decade. This paper reviews pertinent information on the biology, epidemiology, pathology, clinical signs, diagnosis and control of caprine besnoitiosis, together with its similarities to, and differences from, bovine besnoitiosis. The serious economic consequences of besnoitiosis on goat breeding and local meat and hide industries is also considered.     

黄连解毒散固体分散制剂的药效学研究

为了对黄连解毒散固体分散制剂进行药效学研究,采用致病性大肠杆菌和金黄色葡萄球菌为试验菌株考察黄连解毒散固体分散制剂的体外抑菌效果,以仔猪为实验动物考察其临床药效。结果显示：黄连解毒散固体分散制剂的体外抑菌效果是普通散剂的2倍,临床治疗效果比普通散剂提高了30％。黄连解毒散固体分散制剂显著提高了黄连解毒散对猪大肠杆菌病的疗效。     

兔支气管败血波氏杆菌的分离鉴定及药敏试验

山东枣庄某大型兔场送检死亡幼兔病例,经过病原菌的分离鉴定、PCR 检测、药物敏感性试验、敏感动物致病性分析及临床综合治疗等,成功分离到一株对小鼠有一定的致病性的兔败血性波氏杆菌,该菌株对氟苯尼考、多西环素、红霉素等高敏,临床上采取疫苗紧急防疫结合药物治疗的综合防治措施顺利控制了该病的发生。     

National Park stewardship and ‘vital signs’ monitoring: a case study from Channel Islands National Park,California

• 1. Place‐based conservation strategies require that stewards know and understand the targeted ecosystems, restore impaired resources, protect the ecosystems, and connect people wholeheartedly to the places. Knowledge of ecosystem structure and functioning is the cornerstone of stewardship.
• 2. This paper describes the design, implementation, and application of an ecological monitoring programme in Channel Islands National Park, California, USA. Experience from this programme showed that monitoring ecological ‘vital signs’ was a quick, sure, and inexpensive way to discover and track ecosystem dynamics.
• 3. Monitoring ecological ‘vital signs’ determined status and trends of ecosystem integrity and established limits of normal variation of key ecosystem features. It also provided early warnings of situations that required intervention and helped frame research questions to determine chains of cause and consequence.
• 4. The strong influence and probabilistic nature of biological interactions in ecosystems precluded effective use of deterministic modelling to predict ecosystem behaviour accurately. Therefore, ongoing monitoring was required to increase knowledge of system dynamics reliably. The US National Park Service has begun to identify and monitor the ecological ‘vital signs’ in 32 networks of 270 parks.

Published in 2004 by John Wiley & Sons, Ltd.     

视网膜母细胞瘤109例分析

目的：分析视网膜母细胞瘤的发病特点和诊治规律。方法；收集本院近２３ａ来的１０９例ＲＢ病毒，对其临床特点，病理表现，治疗，预后及家系调查作一回顾性分析。结果：７７．１％的病例就诊年龄小于５岁。２２例为双眼发病，９例具有肿瘤家族史。１０９例中以晚期虱阳多见，病理检查大多可见有视神经和巩膜浸润。     

Clinical Therapeutic Effect of Praziquantel Injection on Buffalo Schistosomiasis

To observe the clinical therapeutic effect of 30% praziquantel injection on buffalo schistosomiasis, the sick buffalos naturally infected with Schistosoma japonicum were selected by miracidium hatching method. In experimental clinical trials, sick buffalos were randomly divided into five groups, high-dose (20 mg/kg), middle-dose (10 mg/kg) and low-dose (5 mg/kg) praziquantel injection groups, praziquantel tablet group (30 mg/kg) and positive control group. After the treatment of 30 d, the negative conversion rate of miracidium were 100.0%, 100.0%, 77.8% and 85.7%, respectively, in praziquantel injection groups with the high, middle and low dose and oral medication group. In expanded clinical trials, the sick buffalos were randomly divided into two groups, praziquantel injection group (10 mg/kg, i.m.) and praziquantel tablet group (30 mg/kg). The results showed that, the negative conversion rate of miracidium were all 100% in the former 52 patients and the latter 6 patients after 30 d. The research confirmed that praziquantel injection was significantly effective in the treatment of buffalo schistosomiasis and convenient for administration. It was concluded that 30% praziquantel injection could replace the traditional oral praziquantel tablet for the treatment of buffalo schistosomiasis, and the recommended dose was 10 mg/kg.