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Manuel Morici Marco Di Giuseppe Filippo Spadola Matteo Oliveri Zora Knotkova Zdenek Knotek 《Journal of Exotic Pet Medicine》2018,27(3):11-14
Intravenous alfaxalone, administered at a dose of 5 mg/kg in the jugular vein, was evaluated in 20 leopard geckos (Eublepharis macularius) to ascertain its ability to provide anesthesia. The induction time, time to loss of mandibular tone, interval of deep anesthesia, and full recovery time were 27.5 ± 30.7 seconds (10 to 56 seconds), 1.3 ± 1.4 minutes (11 seconds to 4 minutes), 12.5 ± 2.2 minutes (11.11 to 15.39 minutes), and 18.8 ± 12.1 minutes (10.4 to 52.31 minutes), respectively. A significant reduction in heart rate (74 ± 12.9 beats/minute) was recorded between 2 and 24 minutes after alfaxalone administration. A significant decrease in respiratory rate (26.8 ± 10.1 breaths/minute) was recorded 2 minutes after alfaxalone administration, and respiratory rate remained lower than the basal rate (31.4 ± 3.1 breaths/minute) for 24 minutes but without statistical significance. The intravenous administration of alfaxalone in leopard geckos achieved a rapid onset of anesthesia and a suitable recovery time. Based on this investigation, an afaxalone dose of 5 mg/kg intravenously proved to be suitable for sedation before tracheal intubation. Moreover, the administration route via the jugular vein, was acceptable in leopard geckos; a species in which other venipuncture sites can be challenging or inaccessible. 相似文献
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Döring D Roscher A Scheipl F Küchenhoff H Erhard MH 《Veterinary journal (London, England : 1997)》2009,182(1):38-43
To investigate further the occurrence of fear-related behaviour in dogs in veterinary practice and to evaluate associated factors, 135 dogs were observed under practice conditions within the framework of a standardised test examination and the owners interviewed using a questionnaire. Most dogs exhibited fear reactions, particularly on the examination table, with 78.5% (106/135) categorised as ‘fearful’ based on their behaviour. Unlike weight and castration, age, gender and previous experience were significantly (P < 0.05) associated with fearful behaviour. Male dogs were significantly less ‘fearful’ than females and animals under <2 years were significantly less ‘fearful’ compared with older dogs. Those with only positive previous experiences in veterinary surgeries were significantly less ‘fearful’ than dogs that had a previous negative experience. Fear-related behaviour in veterinary practice is an issue of importance. 相似文献
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随着药剂学与其他学科理论和先进技术的发展,许多新型给药系统在兽医临床的应用有逐步增加的趋势。在众多给药系统中,透皮贴剂通过皮肤敷贴给药后在体内长时间保持稳定有效的血药浓度和治疗作用,为一些慢性疾病和局部镇痛的治疗及预防提供了一种使用简单方便和安全有效的给药方式。国内外已积极开发兽药透皮制剂,并在试验应用中取得了满意效果。文章结合目前国内外兽药透皮贴剂的研究,系统阐述了透皮贴剂的发展现状与特点、影响透皮的因素及该剂型在兽药临床中的使用评价。 相似文献
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基于兽医生物制品学课程特点,结合当前我国畜禽传染病防控发展态势及相关领域人才培养特点,在教材选择、教学内容建设与优化、教学效果评估等方面进行了教学改革探讨。 相似文献
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