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41.
依托"中国知网"的海量文献信息,采用文献计量学方法,利用中国引文数据库、中国学术期刊网络出版总库对《中兽医医药杂志》2001-2010年的发文量、下载量、被引情况、高被引论文栏目及学科分布、作者分布情况、基金论文比等相关指标进行统计分析,探索其中的变化趋势,并对其原因进行分析,以期为编辑部调整办刊及经营策略、更加科学地选题组稿、优化版面及栏目设计等提供参考依据。 相似文献
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Rabies is a neglected disease with an estimated annual mortality of 55,000 human deaths, affecting mainly low-income countries. Over 95% of these cases result from virus transmission through the bite of infected dogs and for this reason there is a real need for a cheap and effective rabies veterinary vaccine to be used in mass vaccination campaigns. In this work, we describe the establishment of a simple platform for the production of a virus-like particles based rabies vaccine using mammalian cells and roller bottles as culture system. Adherent cells were cultured during more than 15 days and VLPs were continuously produced and secreted to the culture supernatant. Immunogenicity and protective efficacy of VLPs were tested through rabies virus neutralizing antibody test and NIH potency test. These viral particles induced high titer of long lasting neutralizing antibodies and protected mice against active virus challenge. Therefore, this development represents a promising platform for the production of a new generation and virus-free rabies vaccine candidate for veterinary applications. 相似文献
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Steele JH 《Preventive veterinary medicine》2008,86(3-4):224-243
Animal diseases are known to be the origin of many human diseases, and there are many examples from ancient civilizations of plagues that arose from animals, domesticated and wild. Records of attempts to control zoonoses are almost as old. The early focus on food-borne illness evolved into veterinary medicine's support of public health efforts. Key historical events, disease outbreaks, and individuals responsible for their control are reviewed and serve as a foundation for understanding the current and future efforts in veterinary public health. Animal medicine and veterinary public health have been intertwined since humans first began ministrations to their families and animals. In the United States, the veterinary medical profession has effectively eliminated those major problems of animal health that had serious public health ramifications. These lessons and experiences can serve as a model for other countries. Our past must also be a reminder that the battle for human and animal health is ongoing. New agents emerge to threaten human and animal populations. With knowledge of the past, coupled with new technologies and techniques, we must be vigilant and carry on. 相似文献
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Hooper BE 《Preventive veterinary medicine》2008,86(3-4):179-187
The evolution of preventive medicine and public health training in professional veterinary medicine curricula is documented. Most veterinary colleges in the US began with a single course in meat hygiene or public health, with a focus on food hygiene issues. These courses laid the foundation for modern veterinary preventive medicine and public health training for veterinary students. Most graduates of veterinary colleges today have extensive training in population health, preventive medicine, and zoonotic diseases. 相似文献