Sepsis-Induced Acute Kidney Injury in Equine: Current Knowledge and Future Perspectives

Sepsis in equine describes a broad range of disorders with different underlying causes and often different prognoses. The syndrome can rapidly progress to septic shock and can result in hypoperfusion with subsequent multiple organ dysfunction including acute kidney injury (AKI). Despite extensive research and progress have been performed in several fields in equine medicine, the incidence as well as the mortality rate of sepsis-induced AKI remains unclear. Although sepsis is considered as the leading cause of AKI, the underlying pathophysiologic mechanisms are not completely understood and still a subject of ongoing debate. The aim of this article is to provide a comprehensive review of the pathophysiology of sepsis-induced AKI, and to outline the diagnostic as well as the therapeutic potentials of the disease.     

Various aspects of barefoot methodology relevant to farriery in equine veterinary practice

The structures of the equine foot have the unique ability to adapt, change shape and restore. There are multiple benefits in shod vs. barefoot or in allowing the horse to be without shoes for a given time period to improve the palmar section of the foot. However, it requires a transition period, a change in the manner in which the foot is trimmed, a commitment from the owner/trainer and, in the case of leaving the horse without shoes permanently, it depends whether the horse can perform the desired function without shoes.     

安徽兔附红细胞体病流行情况调查与治疗试验

以血液涂片直接和染色镜检法为检查的主要手段,对安徽各地的兔附红细胞体病流行情况进行了调查,结果显示：各地普遍存在兔附红细胞体的感染与发病,调查的41家兔场均存在附红细胞体感染（感染率为83,33％-100％）。治疗试验结果表明,联合用药效果较好,贝尼尔＋强力霉素的治愈率为92,7％,贝尼尔＋土霉素的治愈率为85．4％。     

1,6二磷酸果糖治疗中、重度新生儿缺氧缺血性脑病的临床观察

目的:探讨1,6二磷酸果糖(FDP)治疗中、重度新生儿缺氧缺血性脑病(HIE)的价值。方法:将71例中、重度新生儿HIE随机分为2组,FDP与胞二磷胆碱(CDPC)联合应用41例作为观察组,单独应用CDPC 30例为对照组,通过对临床异常神经症状、体征消失时间及20项新生儿神经行为评分作为疗效及预后评价指标。结果:在治疗有效率、显效率及生后d7、d14的20项NBNA评分上,观察组与对照组比较差异有显著性(P<0.05,P<0.01)。结论:早期加用FDP治疗HIE较传统单一用药临床疗效更满意。