A prospective study was conducted to assess the effect of introduction of piglets from farrow-to-finish farms on the global performance of all-in all-out fattening batches in Galicia (NW Spain). Two hundred and thirty-nine fattening batches from 48 fattening farms integrated in a cooperative were used in the study. All-in all-out fattening batches were classified according to the category of farm that supplied the piglets. Origin F was a fattening batch where all feeder piglets came from one or more farrow to feeder units versus origin FF, in case a group of piglets or all piglets of the batch came from farrow-to-finish farms. Productive parameters of fattening batches included in the study were recorded. Crude comparisons of performance of 37 fattening batches from origin F and 202 from origin FF were made. Mixed multiple linear regression models were used to assess the association between type of origin of feeder piglets and the following parameters: feed consumed per market hog, percentage of deaths (mortality) and time to slaughter. In all models, variables with presumable relationships with the outcomes were offered to the models as well as the biologically plausible interaction terms.
Mortality was higher in fattening batches with piglets coming from farrow-to-finish farms (0.67% higher than origin F; P < 0.05). Time to slaughter was longer when feeder piglets were from origin FF (3.1 days longer; P < 0.05).
We found a significant effect of type of origin on feed consumed per marketed hog. Additionally, a significant interaction was found: feed consumed per marketed hog was higher for fattening batches with all piglets from farrow-to-finish farms if slaughtered before 109 days and vice versa. A Monte Carlo simulation model was used to assess the economic impact of using origin F or FF as source of piglets. Results of the model indicated that the difference in expected profit per marketed hog between the types of sources of piglets was small (€11.50, S.D. 1.79 for origin F versus €10.44, S.D. 2.72, for origin FF). 相似文献
A survey was conducted on 176 smallholder dairy farms in Butere/Mumias and Kakamega districts of Western Kenya to establish
the dairy production practices and constraints in the industry. There was low milk production (16.6 kg of milk per capita),
which was attributed to the low number of dairy animals. The average land size was 2.4 ha with only 30.3% being allocated
to pasture or fodder crops. Farmers with large farms (>2 ha) set aside bigger pieces (1.2 vs 0.4 ha) for pasture/fodder crop
cultivation (p < 0.001), owned more (5.25 vs 3.18) dairy animals (p < 0.01) and produced more (9.2 vs 7.5 kg/cow per day) milk (p < 0.05) compared to those on smaller farms of less than 2 ha. The average herd size was 4.2 animals, of which only 45.0%
were in milk, producing 8.0 kg/animal per day. Every kilogram of dairy meal fed increased milk production by 0.68 kg (p < 0.001). Over 90% of milk produced was consumed locally. The public institutions provided 74% of total extension services
to farmers. About 49.5% of total dairy animals were bought from other districts owing to scarcity. 相似文献
The rapid gain in lean mass in neonates requires greater rates of protein synthesis than degradation. We previously delineated the molecular mechanisms by which insulin and amino acids, especially leucine, modulate skeletal muscle protein synthesis and how this changes with development. In the current study, we identified mechanisms involved in protein degradation regulation. In experiment 1, 6- and 26-d-old pigs were studied during 1) euinsulinemic-euglycemic-euaminoacidemic, 2) euinsulinemic-euglycemic-hyperaminoacidemic, and 3) hyperinsulinemic-euglycemic-euaminoacidemic clamps for 2 h. In experiment 2, 5-d-old pigs were studied during 1) euinsulinemic-euglycemic-euaminoacidemic-euleucinemic, 2) euinsulinemic-euglycemic-hypoaminoacidemic-hyperleucinemic, and 3) euinsulinemic-euglycemic-euaminoacidemic-hyperleucinemic clamps for 24 h. We determined in muscle indices of ubiquitin-proteasome, i.e., atrogin-1 (MAFbx) and muscle RING-finger protein-1 (MuRF1) and autophagy-lysosome systems, i.e., unc51-like kinase 1 (UKL1), microtubule-associated protein light chain 3 (LC3), and lysosomal-associated membrane protein 2 (Lamp-2). For comparison, we measured ribosomal protein S6 (rpS6) and eukaryotic initiation factor 4E (eIF4E) activation, components of translation initiation.
Results
Abundance of atrogin-1, but not MuRF1, was greater in 26- than 6-d-old pigs and was not affected by insulin, amino acids, or leucine. Abundance of ULK1 and LC3 was higher in younger pigs and not affected by treatment. The LC3-II/LC3-I ratio was reduced and ULK1 phosphorylation increased by insulin, amino acids, and leucine. These responses were more profound in younger pigs. Abundance of Lamp-2 was not affected by treatment or development. Abundance of eIF4E, but not rpS6, was higher in 6- than 26-d-old-pigs but unaffected by treatment. Phosphorylation of eIF4E was not affected by treatment, however, insulin, amino acids, and leucine stimulated rpS6 phosphorylation, and the responses decreased with development.
Conclusions
The rapid growth of neonatal muscle is in part due to the positive balance between the activation of protein synthesis and degradation signaling. Insulin, amino acids, and, particularly, leucine, act as signals to modulate muscle protein synthesis and degradation in neonates. 相似文献