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331.
Chenhui Liu Xunping Jiang Shaxuan Chi Dongdong Bo Guiqiong Liu 《Reproduction in domestic animals》2021,56(11):1406-1412
Seasonal breeding is widespread in sheep and significantly affects the development of the housed sheep industry. To improve and balance the reproduction performance of sheep, year-round breeding has the goal of modern sheep farming. The tryptophan hydroxylase (TPH), which initiates and regulates biosynthesis of melatonin, is an important player in the formation of mammalian year-round breeding. However, little is known about its role in regulation of sheep seasonal breeding. In this study, a missense mutation, T865G in TPH1 gene was detected in 328 individuals of six Mongolian sheep groups. It was positively selected among Mongolian sheep. This mutation may appear between 13,683 and 350,973 years ago and only exist in Hu sheep now. In Hu sheep, the frequency of allele T was 89.66%, and that of allele G was 10.34%. The TPH1 protein structure and property analysis suggested that this mutation from T to G affect the three-dimensional structure and reduce the hydropathicity of catalytic core. When the allele is T, the protein activity is twice that of the allele G, and their difference was significant (p < .05). In conclusion, T865G is an ancient mutation of TPH1 gene and affects the function of TPH protein, which may contribute to the genetic potentiality of Mongolian sheep to year-round breeding. 相似文献
332.
Yachiyo Fukunaga Tatsuya Ogawa Hodaka Suzuki Yumiko Okada Tomomi Nakazawa Yuko Yamaguchi 《Journal of toxicologic pathology》2021,34(3):245
Unilaterally swollen eyes were histopathologically characterized in four MG-W gerbils. The primary lesions resided in the anterior segment of the eye where neural crest cells play a critical role in embryonic development. They included indistinct filtration angle, unformed canal of Schlemm, hypoplastic iris, and ciliary body. The findings noted in the retina, optic nerve, optic tract, and lateral geniculate nucleus were consistent with the lesions induced following the persistent elevation of intraocular pressure as a result of insufficient drainage of aqueous humor. Thus, the present cases observed in the eyes of MG-W gerbils exemplified the anterior segment dysmorphogenesis associated with inadequate neural crest migration or differentiation, leading to subsequent glaucoma. 相似文献
333.
刘丽梅 《干旱区资源与环境》2013,(4):198-203
中国的旅游业正在慢慢转型,文化与旅游结合的需求越来越明显,国内很多地区已经具备发展文化旅游产业的基础。内蒙古草原文化和旅游资源,是未来旅游业发展品牌形象的重要资源载体,面临着进一步发展的种种机遇。但在发展中存在着诸多问题,今后要充分挖掘利用文化遗产、创意不同文化旅游主题、加强区域间文化旅游资源整合、开发文化内涵丰富的旅游商品、健全强有力的产业协调机制。 相似文献
334.
Rodent pest population outbreaks occur frequently in grassland ecosystems in northern China. The Mongolian gerbil (Meriones unguiculatus) is a dominant pest rodent which is distributed across the semi‐desert grasslands of Inner Mongolia, China. In 2009, we studied the contraceptive effect of levonorgestrel‐quinestrol (EP‐1), concentration 50 ppm, on a wild Mongolian gerbil population. The one‐off contraceptive treatment was compared with a control group using a semi‐monthly live trapping method in the Ordos Semi‐desert Grassland Region of Inner Mongolia. The results show that juveniles were not recruited in spring in the treatment group. Ratios of juveniles in the control and treatment groups showed significant semi‐monthly differences from spring to summer (one‐way ANOVA, F2, 14= 7.53, P < 0.05). Between both groups, annual fluctuations of juvenile and total population densities were significantly different respectively (F2, 14= 4.64, P < 0.05; F2, 18= 7.72, P < 0.05). The contraceptive EP‐1 delayed the normal reproductive pattern of Mongolian gerbil populations. This suppressed birth rates of gerbil populations, reduced their densities, and changed their age structures. The period of EP‐1 baiting should be extended but it could be an ideal method for controlling Mongolian gerbil populations during each breeding season. 相似文献