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41.
Lobetti R Dvir E Pearson J 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2002,16(1):63-68
This study compared the sensitivity of ECG and cardiac troponins to predict cardiac histopathological changes, clinical severity, and survival in canine babesiosis. One control group (n = 9) and 4 groups of dogs with mild uncomplicated babesiosis (n = 8), severe uncomplicated babesiosis (n = 9), complicated babesiosis (n = 8), and babesiosis and concurrent immune-mediated hemolytic anemia (IMHA) (n = 9) were studied. A 1-minute lead II ECG was recorded, and cardiac troponin I (cTnI) and T (cTnT) concentrations in plasma were measured. cTnI concentrations were significantly higher in the complicated (mean, 9.9; SE, +/-5.76) and concurrent IMHA (mean, 6.53; SE, +/-4.32) groups and in the 3 dogs that died of the disease (mean, 22.17; SE, +/-12.85) than in the control dogs (concentration below detection limit of test, -0.3 ng/mL). The 3 nonsurvivors had the most severe cardiac histopathological changes, but no arrhythmia and minimal other ECG changes. Dogs with babesiosis developed a variety of ECG abnormalities, but the abnormalities were not associated with disease severity, outcome, or plasma cardiac troponin concentrations. The exception was the presence of ventricular premature complexes (VPCs), which were associated with high cardiac troponin concentrations. This study showed an association between cTnI concentration and histological changes, clinical severity, and survival and no correlation between ECG abnormalities and histological changes or biochemical evidence of myocardial damage as reflected by cTnI concentrations. From this study, it was concluded that the analysis of plasma cTnI is a feasible and sensitive test and is superior to cTnT in diagnosing cardiac involvement in dogs with babesiosis. 相似文献
42.
ELIZABETH A. BALLEGEER LISA J. FORREST ROBERT JERAJ T. ROCKWELL MACKIE R. JEROME NICKLES 《Veterinary radiology & ultrasound》2006,47(2):228-233
A primary lung tumor in a dog treated with intensity-modulated radiation therapy was imaged approximately 6 weeks and 1-year posttreatment with combined positron emission tomography (PET) and computed tomography, utilizing the radiotracers 18F-fluorodeoxyglucose and 18F-fluorothymidine. These two tracers allowed discrimination of tumor from inflammation, and demonstrated spread of tumor along airways over time after treatment. Fusion of functional imaging with anatomic imaging is a useful tool, particularly in the field of oncology, with the potential for PET markers that delineate tumor from normal or reactive tissue, and potential or actual response to therapy. 相似文献
43.
Computed tomography after contrast medium injection was performed in three mesaticephalic canine cadavers to image the auditory tube. Cadavers were positioned in lateral recumbency for imaging. A myringotomy incision was made in the left tympanic membrane of each dog, and contrast medium was infused into the ear canal and middle ear through a balloon-tip catheter. With this method, contrast medium filled the left bulla and auditory tube in all three cadavers. Computed tomography following contrast medium injection was effective for evaluation of the canine auditory tube. Future studies are required to determine the usefulness, as well as the safety, of this procedure in the evaluation of the auditory tube in other breeds of dogs as well as dogs with otitis 相似文献
44.
Finding cardiovascular disease genes in the dog 总被引:2,自引:0,他引:2
Heidi G. Parker PhD Kathryn M. Meurs DVM PhD Elaine A. Ostrander PhD 《Journal of Veterinary Cardiology》2006,8(2):115-127
Recent advances in canine genomics are changing the landscape of veterinary biology, and by default, veterinary medicine. No longer are clinicians locked into traditional methods of diagnoses and therapy. Rather, major advances in canine genetics and genomics from the past five years are now changing the way the veterinarian of the 21st century practices medicine. First, the availability of a dense genome map gives canine genetics a much-needed foothold in comparative medicine, allowing advances made in human and mouse genetics to be applied to companion animals. Second, the recently released 7.5× whole genome sequence of the dog is facilitating the identification of hereditary disease genes. Finally, development of genetic tools for rapid screening of families and populations at risk for inherited disease means that the cost of identifying and testing for disease loci will significantly decrease in coming years. Out of these advances will come major changes in companion animal diagnostics and therapy. Clinicians will be able to offer their clients genetic testing and counseling for a myriad of disorders. In this review we summarize recent findings in canine genomics and discuss their application to the study of canine cardiac health. 相似文献
45.
GIOVANNA BERTOLINI EDOARDO C. ROLLA ALESSANDRO ZOTTI MARCO CALDIN 《Veterinary radiology & ultrasound》2006,47(5):439-443
The purpose of the present study was to investigate the feasibility and usefulness of three-dimensional (3D) multislice computed tomography (CT) angiography with maximum intensity projection (MIP) and volume rendering (VR) in six dogs with clinical and sonographic findings suggestive of portosystemic shunt. Furthermore, we aimed to estimate the diameter of the portal vein and shunt vessels. MIP and VR reconstructions were performed for each patient and the origin and insertion of all shunt vessels were detected. In addition, 3D reconstructions allowed excellent depiction of vascular morphology and topography. All diagnoses and vessel measurements were confirmed by surgery. 3D multidetector CT angiography is a promising, noninvasive, and accurate method of evaluating dogs with suspected portosystemic shunts. 相似文献
46.
Terry C. Gerros DVM MS John S. Mattoon DVM Stanley P. Snyder DVM PHD 《Veterinary radiology & ultrasound》1998,39(4):322-324
A 7-month-old La Mancha doe was presented with a right head tilt and ventral strabismus while circling to the left. History and physical examination led to a tentative diagnosis of a cerebral abscess. Computed tomography revealed a large, complex mass with ring enhancement in the left cerebral hemisphere, supporting the diagnosis. Postmortem examination confirmed the cerebral abscess. Bacterial cultures yielded heavy growth of Actinomyces pyogenes. 相似文献
47.
FINTAN J. McEVOY 《Veterinary radiology & ultrasound》2007,48(6):528-534
An estimate of the thickness of subcutaneous adipose tissue at differing positions around the body was required in a study examining body composition. To eliminate human error associated with the manual placement of markers for measurements and to facilitate the collection of data from a large number of animals and image slices, automation of the process was desirable. The open-source and free image analysis program ImageJ was used. A macro procedure was created that provided the required functionality. The macro performs a number of basic image processing procedures. These include an initial process designed to remove the scanning table from the image and to center the animal in the image. This is followed by placement of a vertical line segment from the mid point of the upper border of the image to the image center. Measurements are made between automatically detected outer and inner boundaries of subcutaneous adipose tissue along this line segment. This process was repeated as the image was rotated (with the line position remaining unchanged) so that measurements around the complete circumference were obtained. Additionally, an image was created showing all detected boundary points so that sites of measurement could be checked by visual inspection. This paper provides a detailed account of this macro, illustrates the effect of its components on the image, and the applicability of standard image processing techniques to veterinary imaging. 相似文献
48.
49.
Nils-Erik Ahlberg Med Dr Fredrik Hoppe VDM Ulrike Kelter MD† Leif Svensson PHD‡ 《Veterinary radiology & ultrasound》1985,26(2):43-47
The influence of body position on volume and x-ray attenuation of the lungs of three Beagles was investigated with computed tomography. In left and right lateral recumbency, the dependent lung had decreased volume and increased x-ray attenuation compared with ventral recumbency. Volume and x-ray attenuation of the nondependent lung, however, were unchanged. In dorsal recumbency, there was a vertical gradient of x-ray attenuation being increased dorsally and decreased ventrally compared with ventral recumbency where regional differences in x-ray attenuation were not found. Results indicate a risk of overlooking a mass in the dependent pulmonary parenchyma of dogs in lateral and dorsal recumbency. Regional differences in x-ray attenuation of the lungs of dogs can be avoided if the radiographs are obtained with the dog in ventral recumbency. 相似文献
50.