Alopecia Universalis in a Horse

Abstract— Alopecia universalis was diagnosed in a 3-year-old brown Percheron mare. Clinical and histo-pathologic findings in this previously unreported condition in the horse are described.     

Black-hair follicular dysplasia in a New Zealand Huntaway dog

CASE HISTORY: A 6-year-old intact male New Zealand Huntaway dog had slowly progressive alopecia that was first observed at 12 weeks of age.

CLINICAL FINDINGS: Patchy alopecia was confined to the black-haired areas of the body, and was most evident on the head and dorsum of the body; tan-haired areas of skin appeared normal. Histological examination of black-haired skin revealed distended melanocytes and large aggregates of melanin within, and surrounding, the hair follicles and the epidermis. Macrophages distended with melanin were also visible within the perifollicular and superficial dermis, and follicular lumina were often plugged by keratin that contained aggregates of melanin. The follicles were dysplastic and few hair shafts were visible emerging from follicular infundibula within the sections.

DIAGNOSIS: The clinical and histological findings were consistent with black-hair follicular dysplasia (BHFD).

CLINICAL RELEVANCE: This is the first report of BHFD in a dog in New Zealand, and is the first report in a Huntaway. The most significant effect of BHFD is a predisposition to follicular plugging and secondary bacterial skin infections. Due to the hereditary nature of the follicular dysplasias, breeding from affected dogs should be discouraged. Histological examination of the skin is required to differentiate between the different follicular dysplasias as well as differentiating between follicular dysplasia and follicular atrophy due to endocrinopathy.     

花粉高效生发灵的研制及其生发机理初探

报道了花粉高效生发灵(Pollen Great Effect Hair Regenrating Liquid,简称PGE生发灵)的研制、稳定性试验、动物安全性试验、临床疗效观察试验。主要成分分析及质量检测。并从生理生化和毛发营养学的角度简要分析了花粉的营养成分与毛发生长及再生的关系。讨论了PGE生发灵的组方依据、适用范围及其有效率等问题。分析和试验数据说明,PGE生发灵组方科学,质量稳定,疗效显著,适用面广。它作为皮肤涂擦剂安全可靠,无毒副作用,但不能内服。