排序方式: 共有16条查询结果,搜索用时 0 毫秒
11.
The sensitivity of some porcine and bovine mycoplasmas to potent antimicrobial agents was examined. Minimal inhibitory concentration (MIC) values were estimated for M. hyosynoviae, M. hyopneumoniae, M. dispar and M. bovis against enrofloxacin, lincomycin, tetracycline, tiamulin and tylosin, in a liquid medium test and in a disc assay. All 6 examined strains of each species and the respective type strains were significantly inhibited. The greatest sensitivity was noted for tiamulin against strains of M. hyosynoviae with a final MIC50 broth value of 0.025 µg ml−1 and disc value of 0.03 µg per disc. Enrofloxacin was found very potent against M. hyopneumoniae with a final MIC50 of 0.025 µg ml−1 and 0.1 µg per disc, and for M. dispar with 0.05 µg ml−1 and 0.03 µg per disc.Most disc assay estimates in ug per disc were similar to or moderately greater than corresponding final broth figures in µg ml−1. It may be possible to convert observed disc assay values into representative final broth MIC values for use in the clinic. 相似文献
12.
13.
使用乙酸酐对截短侧耳素11'-羟基进行保护,水解掉2-羟基乙酸,与2-巯基乙酸酯化,再与2-二乙氨基乙醇氨化,得到泰妙菌素。工艺中以2-二乙氨基乙醇代替2-二乙胺基乙硫醇作为侧链底物合成延胡索酸泰妙菌素,降低了有毒有害反应物对工业合成路线带来的额外成本。最终质量分数可达到920~960 mg/g。 相似文献
14.
15.
两种抗生素对长途运输肉牛的抗应激和促生长作用及对比研究 总被引:1,自引:0,他引:1
为了探讨延胡索酸泰妙菌素、泰乐菌素对经长途运输后肉牛的抗应激和促生长作用及效果,试验将经长途运输后的27头肉牛随机分为试验1组、试验2组和对照组,每组9头,试验1组和试验2组肉牛运后10 d内每天分别灌服延胡索酸泰妙菌素和肌肉注射泰乐菌素,对照组不做任何处理。结果表明:试验1组肉牛发病率比对照组低8.89%,且平均每头牛体重增长量比对照组多7.150 kg;试验2组肉牛发病率比对照组低15.01%,且平均每头牛体重增长量比对照组多8.710 kg。说明延胡索酸泰妙菌素、泰乐菌素对经长途运输后肉牛的抗应激和促生长均有一定作用,且后者的作用效果优于前者。 相似文献
16.
马玲薯葡萄糖培养基在延胡索酸泰妙菌素菌种选育中的应用 总被引:1,自引:1,他引:0
采用涂布法将延胡索酸泰妙菌素生产菌种TMU10—444分离于不同平板培养基上(生产用麦芽浸膏培养基和马铃薯葡萄糖培养基),置恒温恒湿培养箱中培养成熟后,挑取单菌落、初筛、复筛,采用高效液相色谱(HPLC)法测定效价。结果表明,两种不同平板培养基上的菌落生长有差异,马铃薯葡萄糖培养基上的菌落比对照培养基上的菌落明显长得快;对马铃薯葡萄糖培养基选育的菌株进行了筛选,最终获得4支高于对照生产菌株,分别是2107、2115、2165和2183。此结论为延胡索酸泰妙菌素产生菌菌种选育提供了一种新方法。 相似文献