Transition of Historical Control Data for High Incidence Tumors in F344 Rats

Historical control data of tumor incidence were collected from the control groups (215 animals of each sex) in four recent carcinogenicity studies that were started between 2005 to 2009 (terminally sacrificed between 2007 and 2011) at BoZo Research Center Inc. (Gotemba, Shizuoka, Japan) using Fischer 344 rats (F344/DuCrlCrlj). These data were compared to the previous historical control data (from 1990 to 2004, previously reported) in the same facility. In the results, the incidence of C-cell adenoma in the thyroid tended to increase in both sexes in recent years (30.8% for males and 24.4% for females in 2005-2009) as compared with the previous data (17.4% and 20.1% for males and 11.5% and 11.8% for females in 1990–1999 and 2000–2004, respectively). In addition, the incidences of pancreatic islet cell adenoma in males and uterine adenocarcinoma tended to increase from around 2000 and remained high in recent years (incidences of islet cell adenoma in males of 10.5%, 17.1% and 20.5% in 1990–1999, 2000–2004 and 2005–2009; incidences of uterine adenocarcinoma of 3.3%, 12.0% and 13.5% in 1990–1999, 2000–2004 and 2005–2009, respectively). There was no apparent difference in the incidence of other tumors.     

我国西北地区东部时间序列NDVI数据集重建方法比较研究

高质量、长时序归一化植被指数(NDVI)数据集不仅是连续监测陆地表面特征的基础,也是研究气候与陆地生态系统变化的重要参数。本研究以生态环境较为脆弱的西北地区东部为例,借助多种时间序列重建方法对LTDR NDVI数据集中的噪声进行拟合重建,并结合农业气象资料和高质量NDVI数据,对不同重建方法的拟合结果开展适用性评价分析,结果表明,1)下垫面类型是影响重建方法拟合效果的重要因素。根据不同植被类型或作物生长特点,每种重建方法对其噪声消除能力有所不同;2)在年均NDVI较高(NDVI≥0.3),且NDVI曲线具有明显季节变化的草地、林地以及牧草等作物种植区域内,经过D-L拟合重建的NDVI具有较高的保真能力和适应性;3)在年均NDVI较低(NDVI<0.3),且植被季节生长变化不明显或NDVI曲线不呈季节对称性变化的稀疏植被区,以及以冬小麦为典型作物种植的区域内,经过S-G滤波重建的NDVI数据表现出相对较好的保真能力和适应性。     

基于MODIS数据的中国草地生态体系价值估算研究

在传统的草原生态系统价值估算的基础上,利用遥感技术,以谢高地等人计算出来的各种草地类型单位面积价值量为经济参数,利用2003年MODIS数据估算的中国草原生态系统服务价值约折合US$311.48×108,并从草地类型和省区等角度分别进行区域分析,表明我国草原生态系统服务价值呈现出农牧交错带较高且逐渐向牧区递减的特征,说明牧区草原生态系统退化比较严重,草原生态功能保护意识需要进一步加强。     

Validating a Time Series of Annual Grass Percent Cover in the Sagebrush Ecosystem

We mapped yearly (2000–2016) estimates of annual grass percent cover for much of the sagebrush ecosystem of the western United States using remotely sensed, climate, and geophysical data in regression-tree models. Annual grasses senesce and cure by early summer and then become beds of fine fuel that easily ignite and spread fire through rangeland systems. Our annual maps estimate the extent of these fuels and can serve as a tool to assist land managers and scientists in understanding the ecosystem’s response to weather variations, disturbances, and management. Validating the time series of annual maps is important for determining the usefulness of the data. To validate these maps, we compare Bureau of Land Management Assessment Inventory and Monitoring (AIM) data to mapped estimates and use a leave-one-out spatial assessment technique that is effective for validating maps that cover broad geographical extents. We hypothesize that the time series of annual maps exhibits high spatiotemporal variability because precipitation is highly variable in arid and semiarid environments where sagebrush is native, and invasive annual grasses respond to precipitation. The remotely sensed data that help drive our regression-tree model effectively measures annual grasses’ response to precipitation. The mean absolute error (MAE) rate varied depending on the validation data and technique used for comparison. The AIM plot data and our maps had substantial spatial incongruence, but despite this, the MAE rate for the assessment equaled 12.62%. The leave-one-out accuracy assessment had an MAE of 8.43%. We quantified bias, and bias was more substantial at higher percent cover. These annual maps can help management identify actions that may alleviate the current cycle of invasive grasses because it enables the assessment of the variability of annual grass ? percent cover distribution through space and time, as part of dynamic systems rather than static systems.     

Equine hospital data as a source for study of prevalence and heritability of osteochondrosis and palmar/plantar osseous fragments of Swedish Warmblood horses

Reasons for performing study: Disturbances in skeletal development, primarily osteochondrosis (OC) and palmar/plantar osseous fragments (POF), have been commonly reported as problems in young horses. However, there are few reports of such findings for epidemiological analyses or breeding purposes. Objectives: To evaluate equine hospital data as a possible source of information for genetic evaluations by estimating prevalence and heritability of OC in the stifle, hock and fetlock joints and of POF in the fetlock. Methods: Data on Swedish Warmblood (SWB) horses were obtained from a large equine hospital in south Sweden. Prevalences were based on radiographic examinations of 879 screened horses, mainly evaluated as part of a prepurchase examination and 3639 horses with a reported history of orthopaedic problems. For the heritability study the 2 data sources were pooled and 3199 examined horses with pedigree information were considered for the linear animal model analyses. Results: The overall prevalence of OC was 13% (stifle 9%, hock 6% and dorsal osseous fragments in fetlock [DOF] 10%) and POF 10%. The overall heritability of OC was 0.05 on the visible binomial scale. The corresponding heritabilities for OC in the stifle were 0.03, hock 0.08, DOF 0.10 and POF 0.13. These values correspond to heritabilities of 0.09–0.38 on the underlying quantitative scale. Conclusions and potential relevance: Obtained prevalences and heritabilities were in accordance with other studies, supporting the hypothesis that data regularly obtained from equine hospitals may be a valuable source in studies of inherited disorders such as OC and POF. There is a need for more standardised documentation of diagnoses and consistent recording of identity of examined horses using passports or breed databases. Compilation of results from major clinics is desired in order to cover most progenies of stallions used in a region or nation.     

Demographics of cattle positive for Mycobacterium avium subspecies paratuberculosis by faecal culture,from submissions to the Cork Regional Veterinary Laboratory

The demography of bovine infections caused by Mycobacterium avium subspecies paratuberculosis (MAP) in Ireland is poorly defined. The objective of this study was to describe the demographics of cattle positive to MAP on faecal culture, based on submissions to the Cork Regional Veterinary Laboratory (Cork RVL) from 1994 to 2006. The study focused on all available faecal samples from adult cattle with non-responsive chronic diarrhoea that were submitted by private veterinary practitioners to Cork RVL for MAP culture. For each MAP-positive by faecal culture animal, data were collated from Cork RVL and Cattle Movement Monitoring Scheme (CMMS) records. Johne's disease (JD) was confirmed in 110 animals from 86 herds by the Cork RVL between 1994 and 2006, with a rate of positive cases between 15% and 18% over last four years of the study. Two breeds (Holstein/Friesian or Limousin) made up 78% of submissions. Movements were assessed for the 57 study animals with available movement information, 90% died within one year of the test and 26% tested positive in the herd they were born into. The study provides preliminary information about movement trends and demographics of animals with MAP positive submissions. Although the study area is restricted, it includes the most intensive (and economically-important) dairy region in Ireland. The demographics of JD infection from the study area are in agreement with international reports. Further work is required to determine demographic trends, incidence and prevalence of JD throughout Ireland. It is hoped this work may contribute to the development of a surveillance strategy for MAP by regional veterinary laboratories.     

农业大数据助力现代农业高质量发展

农业大数据对推动我国现代化农业强国建设具有重要的意义,本文较为细致地梳理了农业大数据的发展意义和存在的问题,并对其未来的发展趋势进行讨论。     

提高阅卷与试题分析速度的有效方法探讨

分析了核对、打孔、光照透明、光电机器阅读和扫描等几种快速手工和自动阅卷评分方法。采用我校目前广泛使用的“成绩记载”中的浮动“阅卷面板”鼠标点击，以及自动阅读机与“成绩记载”间的“数据转换”程序，可大大提高成绩录入、成绩分析和试题分析速度。     

Building phenotype networks to improve QTL detection: a comparative analysis of fatty acid and fat traits in pigs

Models in QTL mapping can be improved by considering all potential variables, i.e. we can use remaining traits other than the trait under study as potential predictors. QTL mapping is often conducted by correcting for a few fixed effects or covariates (e.g. sex, age), although many traits with potential causal relationships between them are recorded. In this work, we evaluate by simulation several procedures to identify optimum models in QTL scans: forward selection, undirected dependency graph and QTL-directed dependency graph (QDG). The latter, QDG, performed better in terms of power and false discovery rate and was applied to fatty acid (FA) composition and fat deposition traits in two pig F2 crosses from China and Spain. Compared with the typical QTL mapping, QDG approach revealed several new QTL. To the contrary, several FA QTL on chromosome 4 (e.g. Palmitic, C16:0; Stearic, C18:0) detected by typical mapping vanished after adjusting for phenotypic covariates in QDG mapping. This suggests that the QTL detected in typical mapping could be indirect. When a QTL is supported by both approaches, there is an increased confidence that the QTL have a primary effect on the corresponding trait. An example is a QTL for C16:1 on chromosome 8. In conclusion, mapping QTL based on causal phenotypic networks can increase power and help to make more biologically sound hypothesis on the genetic architecture of complex traits.     

牧草病害诊断系统的知识表示——《中国草业开发与生态建设》专家系统病害诊断

针对牧草病害诊断的特点,结合框架知识表示的分层特点和规则表示法的过程性和不确定性,提出二者相结合的表示方法.该知识表示包括基础库和动态库,前者用来存放已经确定的数据,后者用来存放诊断的中间结果.基础库中又包括基础数据库、基础知识库和媒体库,数据库是一个关系数据库,根据牧草病害诊断的特点,采用分层建库的方式.知识库采用规则方式,按照病害名称建立.媒体库主要是辅助诊断而使用的图片、视频数据.动态库包括动态数据库和动态知识库,动态库的结构与基础库中的基础数据库、基础知识库一样.