科尔沁沙地近300年旱涝时空分布特征研究

科尔沁沙地位于季风气候边缘,旱涝气候演变剧烈。本文利用历史文献资料和实测的降水资料,对科尔沁沙地近300年旱涝气候演变规律进行了较周详地探讨与研究。运用旱涝指数、确定了区域旱涝等级,分析与论述了区域旱涝阶段和相对湿润期、干旱期出现的规律和地域分布特征。     

近43年黄河上游来水来沙变化特点

选取黄河头道拐站实测水沙序列(1960-2002年)资料,对水沙序列进行了多时间尺度和趋势识别的小波分析。结果表明:①黄河上游来水来沙量汛期所占比例减少,而非汛期所占比例增加;在年际变化上,水沙量逐年减少;同时,水沙相关关系具有一定的变化;②黄河上游水沙序列具有相同的多时间尺度(准周期)变化,但同一尺度下,水沙所处的丰枯变化并不一致;③年水沙序列趋势变化基本一致,20世纪80年代以来,两者存在明显减少趋势;但在非汛期,两者的趋势变化有较大区别。     

区域尺度分布式水文模拟的时空分辨率

基于数据实验,就区域尺度分布式水文模拟中时空分辨率匹配问题进行讨论,就分布式水文建模中时空分辨率匹配问题提出建议。结果表明:低分辨率高程数据在区域水文要素空间离散过程中,导致边界错位、高程趋于集中、坡度变缓、河网稀疏失真等不良后果,在区域水文模拟研究中,应根据不同时间尺度对应的科学计算需求,选择适宜的空间分辨率数据进行模型平台构建。     

塔里木河流域下游植被生态风险遥感定量评估

近年来,生态风险评估已被人们所重视,但到目前为止,生态风险评估还没有一套完整的方法体系。以我国最大的内陆河——塔里木河下游为研究区,将遥感、地理信息系统等技术手段与模糊数学方法相结合,根据ERA框架和层次分析思想建立塔里木河下游植被的生态风险评估指标,运用模糊综合评判的方法进行塔里木河下游植被生态风险的遥感定量评估,并在评估结果的基础上进行可视化分析。结果表明:在流域生态风险评估缺乏有效的定量评估方法的情况下,Fuzzy集合论与AHP方法结合的模糊综合评判方法是可行的,具有较高的科学性;运用遥感、地理信息系统(GIS)等技术手段,实现了评估结果的定性、定量和可视化。     

1-O-Alkylglycerol Ethers from the Marine Sponge Guitarra abbotti and Their Cytotoxic Activity

The cytotoxicity-bioassay-guided fractionation of the ethanol extract from the marine sponge Guitarra abbotti, whose 1-O-alkyl-sn-glycerol ethers (AGEs) have not been investigated so far, led to the isolation of a complex lipid fraction containing, along with previously known compounds, six new lipids of the AGE type. The composition of the AGE fraction as well as the structures of 6 new and 22 previously known compounds were established using ¹H and ¹³C NMR, GC/MS, and chemical conversion methods. The new AGEs were identified as: 1-O-(Z-docos-15-enyl)-sn-glycerol (1), 1-O-(Z-docos-17-enyl)-sn-glycerol (2), 1-O-(Z-tricos-15-enyl)-sn-glycerol (3), 1-O-(Z-tricos-16-enyl)-sn-glycerol (4), 1-O-(Z-tricos-17-enyl)-sn-glycerol (5), and 1-O-(Z-tetracos-15-enyl)-sn-glycerol (6). The isolated AGEs show weak cytotoxic activity in THP-1, HL-60, HeLa, DLD-1, SNU C4, SK-MEL-28, and MDA-MB-231 human cancer cells. A further cytotoxicity analysis in JB6 P⁺ Cl41 cells bearing mutated MAP kinase genes revealed that ERK2 and JNK1 play a cytoprotective role in the cellular response to the AGE-induced cytotoxic effects.     

Antioxidant Efficacy of a Spirulina Liquid Extract on Oxidative Stress Status and Metabolic Disturbances in Subjects with Metabolic Syndrome

Lipid peroxidation is associated with the development of some pathologies, such as cardiovascular diseases. Reduction in oxidative stress by antioxidants, such as Arthrospira (formely Spirulina), helps improving this redox imbalance. The aim of the study was to evaluate the effect of the Arthrospira liquid extract “Spirulysat^®” on oxidative markers—in particular, oxidized LDL (oxLDL)/total LDL cholesterol—and isoprostanes and to investigate its impact on lipid and glucose metabolism in the metabolic syndrome subject. A controlled, randomised, double-blind design was conducted in 40 subjects aged 18 to 65 years with metabolic syndrome after a daily intake of Spirulysat^® or placebo for twelve weeks. Blood and urinary samples were collected at three visits (V1, V2, V3) in the two groups for parameters determination. Although the Spirulysat^® group showed a decrease at all visits of the oxLDL/total cholesterol ratio, there was no significant difference compared to the placebo (p = 0.36). The urinary isoprostanes concentration in the Spirulysat^® group was reduced (p = 0.014) at V3. Plasma triglycerides decreased at V3 (p = 0.003) and HDL-cholesterol increased (p = 0.031) at all visits with Spirulysat^®. In conclusion, Spirulysat^® did not change the oxidized LDL (oxLDL)/LDL ratio but decreased the urinary isoprostanes, plasma triglycerides and increased HDL cholesterol, suggesting a beneficial effect on metabolic syndrome.     

碱基编辑技术及其在昆虫中的应用和展望

基因编辑是一种能对生物体基因组特定目标基因进行修饰的一种基因工程技术.近年来,基因编辑技术不断突破与发展,以CRISPR编辑系统为基础的单碱基编辑和先导编辑引起了科研人员的关注,随着基因编辑技术的不断成熟,已成功应用到各种动、植物以及其他生物中,为基因治疗和基因功能研究等方面提供了重要的技术支持.本文主要回顾了CRIS...     

江苏常州地区禽白血病血清学调查研究

为了解江苏常州地区肉鸡禽白血病病毒(ALV)感染情况,本研究采集了该地区2019年7-12月、2020年1-4月肉鸡血清样本1257份,通过ELISA试剂盒检测ALV-A/B、ALV-J、抗原p27阳性率。结果显示：在接受调查的两个地区均存在ALV感染及混合感染,且ALV-A/B感染率(13.13%)均高于ALV-J(5.01%);不同月份阳性率存在一定差异,ALV-A/B、ALV-J均为春夏季阳性率较高,秋冬季逐渐下降趋势;抗体阳性样本中有54.39%的p27抗原阳性率。本次调查为江苏常州地区商品肉鸡ALV净化及防控提供一定的参考依据。     

果蔗脱毒种苗组培快繁技术研究

采用不同浓度的6-BA对果蔗进行了茎尖分生组织的诱导和幼芽增殖试验研究,利用不同状态的培养基对增殖芽进行了培养。结果表明,当6-BA浓度为4-5mg／L时,比较适宜于果蔗茎尖分生组织的诱导。在幼芽增殖前期．6-BA的浓度采用2-3mg／L;在将进入生根阶段时,6-BA的浓度采用0．5-1．5mg／L,有利于获得粗壮的幼苗。果蔗幼芽在增殖阶段。适宜采用液体培养基,可降低成本。