Application of Pushover Method to Seismic Performance Evaluation of Tall Piers for Bridge

For bridge with tall piers, the influence of higher modes on structural responses becomes more evident. Modified MPA method(MMPA) which is based on MPA theory and the concept of “equivalent mode height” is presented. To verify the effectiveness and the degree of accuracy of this method, several Pushover methods including MPA and MMPA methods were adopted to analyze tall piers for bridge, and then compares the results with that in dynamic time-history analysis. It is shown that MPA and MMPA methods can improve computational accuracy comparing with other normal Pushover methods when seismic intensity is lower, whereas the computational accuracy for MMPA methods is superior to that in MPA analysis with the seismic intensity becoming larger.     

甘草查尔酮E对金黄色葡萄球菌的抗菌活性

应用肉汤微量稀释法测定甘草查尔酮E对金黄色葡萄球菌（简称金葡菌）的抗菌活性,并通过溶血试验、Western blot分析和荧光定量PCR试验考察亚抑菌浓度的甘草查尔酮E对金葡菌α-溶血素表达的影响。结果显示,甘草查尔酮E对7株金葡菌的最低抑菌质量浓度为2～8mg/L;亚抑菌浓度的甘草查尔酮E能显著降低金葡菌α-溶血素的表达,且呈现剂量依赖性。     

Pharmacokinetics and distribution of minocycline in mature horses after oral administration of multiple doses and comparison with minimum inhibitory concentrations

Reasons for performing study: Minocycline holds great potential for use in horses not only for its antimicrobial effects but also for its anti‐inflammatory and neuroprotective properties. However, there are no pharmacokinetic or safety data available regarding the use of oral minocycline in horses. Objectives: To determine pharmacokinetics, safety and penetration into plasma, synovial fluid, aqueous humour (AH) and cerebral spinal fluid (CSF) of minocycline after oral administration of multiple doses in horses and to determine the minimum inhibitory concentrations (MIC) of minocycline for equine pathogenic bacteria. Methods: Six horses received minocycline (4 mg/kg bwt q. 12 h for 5 doses). Thirty‐three blood and 9 synovial fluid samples were collected over 96 h. Aqueous humour and CSF samples were collected 1 h after the final dose. Minocycline concentrations were measured using high pressure liquid chromatography. The MIC values of minocycline for equine bacterial isolates were determined. Results: At steady state, the mean ± s.d. peak concentration of minocycline in the plasma was 0.67 ± 0.26 µg/ml and the mean half‐life was 11.48 ± 3.23 h. The highest trough synovial fluid minocycline concentration was 0.33 ± 0.12 µg/ml. The AH concentration of minocycline was 0.09 ± 0.03 µg/ml in normal eyes and 0.11 ± 0.04 µg/ml in blood aqueous barrier‐disrupted eyes. The mean CSF concentration of minocycline was 0.38 ± 0.09 µg/ml. The MIC values were determined for 301 isolates. Minocycline concentrations were above the MIC₅₀ and MIC₉₀ for many gram‐positive equine pathogens. Potential relevance: This study supports the use of orally administered minocycline at a dose of 4 mg/kg bwt every 12 h for the treatment of nonocular infections caused by susceptible (MIC≤0.25 µg/ml) organisms in horses. Further studies are required to determine the dose that would be effective for the treatment of ocular infections.     

肌苷酸的鲜味评价试验

试验对肌苷酸(IMP)及其与谷氨酸钠(MSG)的协同鲜味呈味作用进行了感官验证。试验结果表明,IMP的鲜味呈味作用显著,肉品IMP含量的差异会对肉品总体风味产生一定作用,作用大小与IMP和MSG等其它风味物的协同作用有关。     

Influence of Transverse Flexural Crack on Chloride Penetration in Concrete

The mechanism for chloride penetration in cracked concrete and its major impact factors were analyzed. As a result, a revised chloride diffusion model based on Fick's Law was built by dual porous medium model. Then several cracked reinforced concrete beams self-anchored with sustained flexural loads were immersed in the 5% NaCl solution with the condition of dry-wet cycles. After 15 times of dry-wet cycles, the rapid chloride testing (RCT) was used for the determination of chloride ion content of the powder at each cracked sections. The test results show that: 1) with the condition of dry-wet cycles, the chloride content will occur a peak in the surface 20mm concrete, so the depth for surface convection zone can be assumed to be 15~20 mm; 2) when the crack width is less than 0.3mm, the equivalent chloride diffusion coefficient increases steadily, which agrees well with model's prediction; when the crack width is larger than 0.3mm, the equivalent chloride diffusion coefficient augments rapidly and influence of convection on chloride penetration becomes more significant; 3) the deterioration factor for equivalent chloride diffusion coefficient in flexural cracked concrete is directly correlative with crack width, which can be expressed by second order power function or separate function.     

中国农田畜禽粪尿磷负荷量及环境风险分析

准确掌握不同地区畜禽粪尿和磷负荷量及其环境风险,为畜禽养殖总量控制、合理布局和还田利用提供决策依据。基于统计数据和文献资料,利用磷的猪粪当量(P)估算了我国畜禽粪尿量和各类畜禽粪尿比例的时空变化,分析和评价了当前各省份畜禽粪尿和磷资源量及其土地负荷量和污染风险,并根据畜禽粪尿还田率估算了当前各省份畜禽粪尿及其磷还田量,并进行环境风险评价。结果表明:中国畜禽粪尿猪粪当量(P)及其磷量1978年至2005年快速增加,2006年至2016年保持稳定。截止2016年,猪粪当量(P)约21.23亿t,磷量约545万t,比1978年均增长123%,华北地区畜禽粪尿猪粪当量(P)及其磷量最大,约占全国总量的23%和9%。区域水平上,按耕地面积计算,东南和西南地区负荷量较大,为Ⅴ级,有严重污染风险,按农作物种植面积计算,东南和西南地区较大,为Ⅳ级,有较严重污染风险,按农用地计算,东南、长江中下游和华北地区负荷量较大,为Ⅳ级,有较严重污染风险。省级单元上,湖南负荷量最大,其次是北京、广东和河南,这些省份为Ⅴ级,有严重污染风险。全国畜禽粪尿猪粪当量(P)及其磷还田量分别为11.51亿t和295万t,折合成单位农用地面积分别为3.1 t·hm(~-2)和8.0 kg·hm(~-2)。区域上东南地区还田最多,分别为10.3 t·hm(~-2)和26.3 kg·hm(~-2),为Ⅲ级,有污染风险,其次是华北和长江中下游地区,为Ⅱ级,稍有污染风险,而东北、西南和西北地区相对较低,为Ⅰ级,无污染风险。省级单元上湖南和北京还田较多,为Ⅳ级,有较严重污染风险,华北、长江中下游、东南地区的多数省份和部分西南地区省份农用地畜禽粪尿磷还田量接近或大于50%单位土地面积畜禽粪尿磷的年施用限量,具有较高的污染风险。研究表明,不同区域和省份畜禽粪尿磷负荷量和还田量污染风险具有较大差异,但多数省份尤其华北、长江中下游、东南地区的畜禽粪尿磷污染风险较大。     

基于作物营养当量修正产量比系数法的农用地质量分等

产量比系数是农用地分等中的基础参数,由于不同地区产量比系数确定的基础不同,分等结果无法达到全国可比。为提高农用地分等结果的全国可比性,该文依据供给人体所需能量和营养的蛋白质、脂肪、碳水化合物、矿物质、维生素等营养素在不同作物间可比这一特点,选取20种营养素指标和9种标准耕作制度规定作物,构建营养当量修正法,通过计算不同作物"营养当量"来修正产量比系数,并选取北方以小麦为基准作物的河北省曲周县土地整治项目区和南方以水稻为基准作物的江苏省宜兴市丁蜀镇作为案例进行实证,对比通过营养当量修正法和最高产量比法计算产量比系数所得出的农用地自然等的差异。研究结果显示,曲周县土地整治项目区自然等指数区间由2 060～2 896上升为2 516～3 580,等别序列由11～15等上升为13～18等;丁蜀镇自然等指数由区间由2 460～2 918下降为2 013～2 393,等别序列由13～15等下降为11～12等,2个研究区间的农用地自然等别差异扩大。该文可以为相关研究提供参考,为完善农用地质量分等体系提供借鉴。     

基于角度指数的油菜叶片等效水厚度估算研究

叶片等效水厚度(EWT)是评估油菜生长状态的一个重要参数。为快速准确估算油菜叶片EWT,选择9个常用的植被水分指数(WI、PRI、NDVI、NDII、NDWI、MSI、PWI、GVMI、NDMI),在6个已有角度指数(β_SWIR1、SANI、SASI、ANIR、NANI、NASI)基础上,提出2种角度比值指数(SARI、NARI),并根据油菜叶片水吸收谷峰高光谱特征,提出基于水吸收谷1 450 nm和1 930 nm的8种改进型角度指数,利用以上25种角度指数估算不同施氮水平下苗期、蕾薹期以及不区分苗期、蕾薹期情况下的油菜叶片EWT。结果表明,苗期ANI₁₄₅₀、ASI₁₄₅₀、MSI、GVMI、NDII估算效果较好,R^2均达到0.81以上;蕾薹期ANI₁₉₃₀、ASI₁₉₃₀、NASI、SANI、GVMI、SARI效果最好,R^2均达到0.71以上;在不区分苗期、蕾薹期的情况下,改进型角度指数ANI₁₄₅₀、ASI₁₄₅₀效果最好,R^2均达到0.832,可以在不区分苗期、蕾薹期情况下对油菜叶片EWT进行估算,适用性更广。本研究提出的改进型角度指数不仅丰富了已有角度指数,且提高了其反演油菜叶片EWT的精度,为快速精确估计油菜叶片EWT提供了新的研究思路。     

光滑双向渐进结构优化法拓扑优化连续体结构频率和动刚度

针对双向渐进结构优化(bi-directional evolutionary structural optimization, BESO)方法的单元过删除问题,提出了光滑双向渐进结构优化(smooth bi-directional evolutionary structural optimization, SBESO)方法,通过引入权重函数更新单元的质量与刚度矩阵,控制单元删除率以使低效单元逐渐从设计域中删除。以连续体结构固有频率最大化为目标,提出了一种基于SBESO的频率优化方法,对比分析了常函数、线性函数和正弦函数等不同权重函数对连续体结构优化的影响。将等效静载荷(equivalentstatic loads,ESL)方法与SBESO方法相融合,提出了动载荷作用下连续体结构的动刚度优化方法。数值算例表明,SBESO方法通过调节单元删除率和权重函数,控制低效单元在结构设计域中逐渐被删除,有效抑制了单元的过删除问题。采用线性和正弦权重函数,更有利于获得连续体结构的频率最优拓扑解。随单元删除率的减少,动刚度最优拓扑解的结构边界逐渐光滑,而且逼近于同一构形。由此,所提出的SBESO方法完善了BESO方法的优化准则,对于解决连续体结构动力学优化设计问题具有较为重要的理论意义。     

白银市土地利用变化对生态系统服务价值的影响

为了明确白银市土地利用状况与生态系统服务价值之间的关系,进一步确定白银市各土地利用类型对生态系统的影响程度。本研究选择当量因子法评价白银市2009—2017年土地利用状况、生态系统服务价值以及两者之间的关系。结果表明:（1）2009—2017年,白银市生态系统服务价值总量从56.75亿元下降到56.49亿元,总体呈下降趋势,各项生态系统功能和生态系统服务都呈下降趋势;草地生态系统服务价值减少了2549.18万元,减少最多,人口对生态系统负荷呈减轻趋势;（2）白银市土地利用类型对生态系统服务价值具有较大的影响,主要受建设用地增加较多,草地和林地面积减少影响较大,在以后的发展中,要从保护生态用地、挖掘存量建设用地方面,探索出一条生态优先、绿色发展的新路子。