Genetic and non-genetic factors influencing KLH binding natural antibodies and specific antibody response to Newcastle disease in Kenyan chicken populations

This study aimed at investigating the influence of genetic and non-genetic factors on immune traits to inform on possibilities of genetic improvement of disease resistance traits in local chicken of Kenya. Immune traits such as natural and specific antibodies are considered suitable indicators of an individual's health status and consequently, used as indicator traits of disease resistance. In this study, natural antibodies binding to Keyhole Limpet Hemocyanin (KLH-NAbs) was used to measure general disease resistance. Specific antibodies binding to Newcastle disease virus (NDV-IgG) post vaccination was used to measure specific disease resistance. Titers of KLH-NAbs isotypes (KLH-IgM, KLH-IgG and KLH-IgA) and NDV-IgG were measured in 1,540 chickens of different ages ranging from 12 to 56 weeks. A general linear model was fitted to determine the effect of sex, generation, population type, phylogenetic cluster, line, genotype and age on the antibody traits. A multivariate animal mixed model was fitted to estimate heritability and genetic correlations among the antibody traits. The model constituted of non-genetic factors found to have a significant influence on the antibody traits as fixed effects, and animal and residual effects as random variables. Overall mean (±SE) concentration levels for KLH-IgM, KLH-IgG, KLH-IgA and NDV-IgG were 10.33 ± 0.04, 9.08 ± 0.02, 6.00 ± 0.02 and 10.12 ± 0.03, respectively. Sex, generation and age (linear covariate) significantly (p < 0.05) influenced variation across all the antibody traits. Genotype effects (p < 0.05) were present in all antibody traits, apart from KLH-IgA. Interaction between generation and line was significant (p < 0.05) in KLH-IgM and NDV-IgG while nesting phylogenetic cluster within population significantly (p < 0.05) influenced all antibody traits, apart from KLH-IgA. Heritability estimates for KLH-IgM, KLH-IgG, KLH-IgA and NDV-IgG were 0.28 ± 0.08, 0.14 ± 0.06, 0.07 ± 0.04 and 0.31 ± 0.06, respectively. There were positive genetic correlations (0.40–0.61) among the KLH-NAbs while negative genetic correlations (−0.26 to −0.98) were observed between the KLH-NAbs and NDV-IgG. Results from this study indicate that non-genetic effects due to biological and environmental factors influence natural and specific antibodies and should be accounted for to reduce bias and improve accuracy when evaluating the traits. Subsequently, the moderate heritability estimates in KLH-IgM and NDV-IgG suggest selection possibilities for genetic improvement of general and specific immunity, respectively, and consequently disease resistance. However, the negative correlations between KLH-NAbs and NDV-IgG indicate the need to consider a suitable approach that can optimally combine both traits in a multiple trait selection strategies.     

河川基流分割法在山丘区地下水资源量评价中的运用

山丘区河川基流分割方法很多，采用不同方法的分割成果不尽相同。在地下水资源评价中，根据云南省自然地理独特，气候复杂多样，降水量丰沛，洪水频繁，河川径流过程线普遍呈连续多峰型的特性，寻求一种既能满足水资源综合规划要求，又符合云南实际分割河川基流量的方法，是地下水资源评价中的重要内容。采用适宜水均衡法和直线斜割法的径流资料分割河川基流量，求出两种方法之间的换算系数，修正水均衡法的分割成果，一是达到了以直线斜割法统一分割河川基流量的目的；二是提高了山丘区地下水资源量评价的精度，为探索山丘区地下水资源量及时空分布规律提供技术支撑。     

Multilevel Fuzzy Theory Evaluation of the Tourism Resources in the Three Gorges Reservoir

Complexity of mutual act and different sensation of different tourists are important factors influencing regional tourism resources evaluation. Fuzzy mathematic method can be used to up quantitative evaluation method on tourism resources evaluation. Taking Wushan Small Three Gorges as an example, the author carries out the evaluation of the tourism resources in the Three Gorges Reservoir. At the same time, the authors consider that five factors, such as improvement of the comunication of tourism resources, quickening the Steps of urbanization in reservior area, must be done well.     

A STUDY ON HEAT AND MOISTURE STATE OF HULL LAYER FOR THERMAL INSTULATION OF A COLD STORAGE

This paper analyses the thermal moist characteristics of the hull layer beside an air layer at lower temperature in an envelope for a cold storage and presents a new method of waterproof by air layer. With test data from engineering practice, the theory on the barrier of self moisture proof at the surface sublayer of the hull layer in an attic on a cold storage is proven. The dried zone about three phase point is confirmed. It is a new knowledge for thermophysics on thermal design of a cold storage with an optimum thermal performance.     

PTGS/ RNAi的作用机制及其应用

论述了双链RNA对同源基因的表达进行特异性的封闭而引起的转录后的基因沉默（PTGS/ RNAi）现象, PTGS/ RNAi的作用机理，作用模型，参与这一过程的酶、基因、起始因子和作用因子，介绍了PTGS/ RNAi在基因组功能研究、基因的时空表达调控以及在作物改良等方面的应用。     

面向MC提升企业柔性的概念模型分析

大规模定制(简称MC)是应对目前市场激烈竞争的一种有效方式,它对企业的柔性能力提出了更高的要求。本文基于资源和能力角度,建立了面向MC提升企业柔性的整体模型,通过分析企业需要向MC转变的程度以及企业已具备的柔性与企业的理想柔性之间的差距,确定企业提升柔性的途径,并利用系统动力学方法给出了相应的因果关系结构图。     

区域水资源可持续利用的未确知测

针对水资源系统是一个具有未确知性特征的复杂大系统。在未确知测度空间基础上，构建了区域水资源可持续利用评价的未确知测度模型，并将该模型应用于西安市水资源开发利用程度的评价。通过单指标未确知测度、多指标综合测度计算以及指标定权等过程，实现对各分区水资源开发利用程度的综合评价与排序。实例研究表明，运用未确知测度模型进行区域水资源可持续利用问题研究，理论上是可行的，评价结果是可信的，这为信息不确定条件下的区域水资源可持续利用评价提供了一种新方法。     

基于GIS的黄河下游分布式水资源模拟

分布式水文模型是水文界研究的焦点问题之一。该研究选用黄河下游流域作为典型研究流域，应用ARC／INFO技术和遥感信息、国内最新水资源调查资料和我国自行开发的LL-Ⅱ分布式水文模型对流域的水资源量进行模拟计算。黄河下游流域内主河道由于泥沙的不断淤积属于典型的地上悬河，而且该地区随着经济的不断发展，人类活动对水资源的影响日益显著，尤其是跨流域调水的影响。本研究充分考虑各种人类活动对水资源的影响，对径流过程进行连续模拟，并取得了较好的模拟结果。     

小型农村水利改革思路

在分析小型农村水利的特点和性质的基础上,理清了小型农村水利改革的思路。认为：小型农村水利具有工程小、数量多、分布面广,地位重要但易受忽视,涉及范围广、服务功能多、公用性、垄断性、群众性、政策性、公益性、系统性和整体性强,季节使用、经营管理难等特点。改革的核心要按照“谁受益,谁负担,谁投资,谁所有”的原则,组建用水合作组织,明晰所有权。改革的关键是把所有权与经营管理权分开,采用灵活多样的形式加强经营管理。改革的实质是建设与管理制度改革,不能简单理解为“产权制度改革”。     

景观生态学原理在河道生态岸堤构

分析了传统水工设计中岸堤(岸坡)构建的弊端、简要介绍了国内外学者在河流的生态整治方面的思想与观点。从景观生态学的角度着重介绍了岸堤(岸坡)生态系统的组成和主要特征、生态岸堤的多种功能和景观生态学内涵；提出了在生态岸堤设计中的坚持生态优先，同时重视景观性和稳定性；根据使用材料的不同对岸堤进行分类,对生态岸堤的植物群落的构建进行分析。本文可为从而为生态岸堤的构建、河流、洪泛区的治理提供一定的思路和参考。