基于物联网的矿山安全系统

文章分析总结了当前数字矿山中物联网的矿山安全现状,提出一种固定感知与移动感知相结合,孤立感知与联合感知相结合的矿山安全系统方案,简要分析了该方案的科学性和可行性。     

整体式碾压混凝土重力坝的抗滑稳定性分析

文章采用三维弹塑性力学有限元法对整体式碾压混凝土重力坝的应力和抗滑稳定性进行了计算分析，并与刚体极限平衡法的计算结果进行了比较。结果说明，整体式碾压混凝土重力坝的应力和稳定条件较好，狭谷中的中低坝采用整体式碾压混凝土重力坝，具有明显的经济效益，在采取了严格的温控措施后，可推广采用。     

小型农产品分选机设计与试验

针对家庭农场及小规模营销的需要,设计了基于机器视觉的小型农产品分选机。农产品在平胶带上形成多通道阵列式输送,以DSP作为机器视觉单元的核心,采集一帧图像可分析多个通道,并根据农产品的形状、颜色等图像特征进行分选。在水平输送速度为9.2 cm/s、农产品输送间隔为16 cm、4通道并行输送的条件下,选用核桃、红枣及栗子3种农产品进行了分选机性能测试。试验表明,机器能够可靠工作;核桃、红枣和栗子的分选准确性分别为91.66%、94.79%和97.39%;分选速度达8 800个/h。因此采用DSP芯片作为小型分选机的机器视觉核心是可行的,可以为农产品分选机的小型化、低成本提供技术支持。     

螺旋弯管内流动与传热特性的数值模拟

针对螺旋弯管内的流动与传热特性,以螺旋弯管传热试验中试验件模型为研究对象,基于Realizable k-ε湍流模型、第一类热边界条件下的薄壁热阻模型,对不同进口来流条件下,采用Fluent对螺旋弯管内水的流动与换热进行数值模拟.计算得到了螺旋弯管内速度场与温度场的分布,通过数值模拟结果与试验结果的比较,验证了数值模拟方法的正确性.结果表明:随着进口来流雷诺数的增大,螺旋弯管内的二次流迪恩涡核心向弯管管壁扩张;在螺旋弯管小曲率比、来流雷诺数2 280~6 000内,螺旋弯管的强化换热综合性能最佳;对模拟结果数据利用多元线性回归法,推导出螺旋弯管内换热努赛尔数、进出口压力降的准则关系式.研究结果可为螺旋管式换热器设计与优化提供一定的参考依据.     

Progress in RNA-binding protein HuR and its roles in development of hepatocellular carcinoma

RNA-binding proteins （RBP） are molecules with a variety of biological functions discovered in recent years. Among them, HuR is an important RBP, widely expressed in various tissues of the body, and is a member of the Hu/embryonic lethal abnormal vision （ELAV） protein family. It mainly affects the expression levels of target genes in the cells by regulating the stability and/or translation efficiency of the mRNA of the genes, thus participating in the regulation of cell life activities. In recent years, more and more studies on HuR have revealed its important role in inflammation and cancer. This review summarizes the functions of HuR and probes into the regulation of HuR functions. In addition, the roles of HuR in the occurrence and development of hepatocellular carcinoma （HCC） are also discussed, which provides important information for exploring the pathogenesis, biomarkers and therapeutic targets of HCC.     

p300/p53/Smad3 pathway involved in aging-related atrial fibrosis in human atrial fibroblasts

AIM To investigate the role of p300 in aging-related atrial fibrosis in human atrial fibroblasts （HAFs） and its potential mechanism. METHODS HAFs were obtained from human left atrial tissue, and the senescence model was established by cell passage. Senescence-associated β-galactosidase （SA-β-Gal） staining was used to detect the cell senescence, and Western blot was used to determine the protein levels of p300, p53, Smad3 and other senescence and fibrosis associated proteins in HAFs. RESULTS Compared to passage 3 HAFs, the proportion of senescent cells, and the protein levels of p300, p53, p-Smad3 and other senescence and fibrosis associated proteins were increased in HAFs at passage 7 and 11 （P<0.05）. After treated with curcumin （a p300 inhibitor） or transfection with p300 small-hairpin （sh） RNA plasmid, the protein levels of p300, and the senescence and fibrosis associated proteins were decreased in HAFs at passage 7（P<0.05）. Up-regulation of p300 by transfection with p300 over-expression plasmid increased the protein levels of p53, Smad3 and MMP-2 in HAFs at passage 3 （P<0.05）. CONCLUSION p300/p53/Smad3 signaling pathway plays an important role in aging-related atrial fibrosis in HAFs.     

吴茱萸嫁接方法试验

试验表明:5种嫁接方法苗木成活率均在80％以上,其中以贴枝接和长块削芽接为最高,平均成活率达95％以上,但从快速繁育苗木着眼,以长块削芽接为好。嫁接适期以3月中旬树液流动时为最好。嫁接苗当年在圃地就能开花结果。     

数据仓库逻辑建模的初步探讨

针对逻辑建模在数据仓库构建过程中的重要性,介绍了数据仓库创建的基本步骤,并利用实例深入而详细地研究了逻辑模型的设计,分析了几种逻辑模型的特点及其使用场合。     

JAZ蛋白介导的茉莉酸信号传递

当植物受到生物或非生物因素胁迫时,体内会合成茉莉酸类物质,启动自身的防御反应。茉莉酸途径的抑制因子JAZ(Jasmonate ZIM-domain)蛋白近期被确认,该文对JAZ蛋白在茉莉酸信号传递中的作用作一综述。