陆九渊"六经注我"的生命实践诠释学

陆九渊提出:“六经注我,我注六经。”又说:“学苟知道,六经皆我注脚。”在他看来,六经乃圣人的“写心之书”。圣人之心与我之本心不异,如能照自己的本心天德去做,便是真能发挥六经者。堂堂正正地做人,是人生第一等的学问。因此人应致力于道德实践,成就完美人格。果能如此,六经便成为自己的注脚。陆九渊无一部经学注疏之作,他以生命实践为经典诠释的形式,相比之下,儒者注经成了等而次之的学问了。     

A prospective,randomized, double-blind,placebo-controlled multisite,parallel-group field study in dogs with osteoarthritis conducted in the United States of America evaluating bedinvetmab,a canine anti-nerve growth factor monoclonal antibody

ObjectiveBedinvetmab, a fully canine anti-nerve growth factor monoclonal antibody, was evaluated in dogs for control of osteoarthritis-related pain in a study conducted to support registration in the USA.Study designRandomized, double-blind, placebo-controlled, multicenter, parallel-group study.AnimalsGeneral practice client-owned dogs with osteoarthritis (n = 272).MethodsDogs were block randomized 1:1 to placebo (saline, n = 137) or bedinvetmab (n = 135; 0.5–1.0 mg kg^–1) administered subcutaneously, once monthly. The primary end point, day 28 Canine Brief Pain Inventory (CBPI) treatment success (TS), required pain severity score (PSS; 0–10) decrease ≥1 and pain interference score (PIS; 0–10) decrease ≥ 2. CBPI TS rates [and number needed to treat (NNT)], change in scores [and standardized effect size (ES)], change in quality of life (QoL) and bedinvetmab half-life were calculated.ResultsSignificant (p < 0.05) improvement with bedinvetmab over placebo occurred (days 28, 42, 56, 84) for CBPI TS. Of cases evaluable for day 28 CBPI TS (placebo, n = 131; bedinvetmab, n = 128), success rates were 36.6% and 47.4%, respectively (p = 0.0410) (NNT, 9.3; PSS and PIS ES, 0.3). CBPI TS increased after the second dose in both groups, plateaued for bedinvetmab at day 42 and decreased for placebo beginning day 84. Day 84 NNT (4.3), PSS (0.4) and PIS (0.5) showed continued improvement with monthly dosing. After the first dose, mean (± standard deviation) bedinvetmab half-life was 19.1 (8.3) days. Adverse events were similar between groups and not considered treatment-related. There was a significant effect of bedinvetmab versus placebo on all CBPI components (PIS, PSS, QoL).Conclusions and clinical relevanceThese results corroborated those previously reported and provide further support of safety and effectiveness of bedinvetmab (0.5–1.0 mg kg^–1) administered subcutaneously at monthly intervals to dogs for control of osteoarthritis-related pain.     

复方柴胡散治疗鸡尿酸盐沉积效果初探

鸡尿酸盐沉积病是由多种病因引起的肾脏机能障碍的总称。发病时间长,死亡率高。主要表现为肾尿酸盐沉积,肿胀、充血、出血。轻者使雏鸡生长受阻、成鸡生长性能降低,重者导致大量死亡。尿酸盐沉积为一种慢性疾病。日粮中蛋白质含量过高、高钙日粮或高钙低磷日粮、维生素缺乏、药物慢性中毒、某些传染病及其它若干因素都可引发本病。目前临床上尚无特效的治疗方法,而且治愈率较低,治疗操作不便等因素,给养鸡业带来一定的经济损失。此项实验以柴胡方剂为主要药物,以清热、通便、理气为治疗原则。试验药物具有操作简便、治愈率高、经济实惠的优点。通过人工复制病例和鸡场自然病例的试验,表明试验药物对该病治愈率达到90%以上。     

Experimental Study of Multifunctional Acid to Deliquesce Stratum-jam

Aiming at the oneness of acid to deliquesce stratum-jam applied in scene at the present time,which is incapable of deliquescing complex dirty simultaneously,this article confects a new multifunctional O/W acid.This acid is an emulsified mixture containing 15% hydrochloric acid as its extro-posture,high dissolved oil as its internal state under the function of some proper exterior active reagent.It is composed of 0.5%OP-10,0.5%Span80,0.2%Tween80,0.06%imidazole and 0.01%twelve-alcohol,and the content of oil is equal to the acid content.It can be indicated that this acid has good ability of resolving mineral(CaCO_3,MgCO_3) and organic compound(mainly colloidal bitumen) when it was poured into the stratum,so that it can deliquesce oleic stratum-jam,resume and improve the penetrability of stratum,boost the ability of liquid flowing up.     

鸡新城疫油佐剂灭活疫苗的研究

采用ＮＤ Ｌａｓｏｔａ株为种毒，福尔马林为灭活剂，７号白油为佐剂，吐温８０、司本８０为乳化剂，硫柳汞为防腐剂，高压匀浆泵为乳化工具，研制出ＮＤ油佐剂灭活疫苗。其剂型为双相型（Ｗ／Ｏ／Ｗ），呈稀薄乳状液，粒度为１ｕｍ左右，粘度≤１ｓ，通针性好。４￣８℃有效保存期１年。效力≥７０ＰＤ５０，最早产生免疫时间为１２天（１００％保护），生产中常用免疫剂量为２月龄内每只０．５ｍｌ，２月龄以上每只１．０ｍｌ皮下     

福建省甘薯种质资源鉴定与评价

征集甄别保存甘薯种质资源606份,编写出品种目录,拍摄了彩色图谱册;摸索出适合福建省气候特点的田间种植、薯块贮藏、老蔓越冬和茎尖脱毒试管苗4种方法相结合的安全保存方法;首次在相同条件下同时完成了对保存的品种资源抗蔓割病、薯瘟病的鉴定,8种主要营养成份的分析及鲜薯与薯干产量的测定,筛选出抗蔓割病资源212份、抗薯瘟病资源109份、高干率资源14份、高淀粉资源12份、高水溶性糖资源13份、高粗蛋白资源13份、高粗脂肪资源12份、低粗纤维资源12份、高维生素C资源12份、高胡萝卜素资源12份,初步摸清了这些品种的分布情况;应用Borlanddel-phi7.0为设计集成环境和通用SQL方式查询程序模块创建了资源数据库;建立了107份骨干资源圃。     

极化型静电分级机设计理论

通过极化型静电分级机的结构介绍及种子在静电场中的运动学特性分析,提出了有关种子和静电场的假说,建立了种子在静电场中的运动方程。通过对种子在静电场中的运动特性研究,发现种子的极化力质比是影响极化型静电分级机分离质量的重要因素,是设计极化型静电分级机的关键参数;应通过大量的试验来建立种子极化力质比数据库,满足极化型静电分级机设计的需求。     

论压弯构件

钢筋混凝土轴心受力构件、受弯构件和偏心受压构件在力学行为上有一个共同的特征,即构件的材料纤维均处于单向应力状态。为便于分析比较,特将这三类构件的力学性能一起讨论。     

引黄济津应急调水工程河北段输水能力计算

针对引黄济津应急调水工程河北段的输水能力进行了研究。渠段的输水能力是指渠段所能通过的最大入流量，即渠段的首端断面所能通过的最大流量。根据引黄济津应急调水工程近4年的实测数据，构建了适于干河床水流推进过程渗漏损失的改进模型、小水深情况下的糙率加大模型，并采用均匀试验优选方法对水力参数进行了反演，利用非恒定流模型对引黄济津河北段渠系输水能力进行了计算。结果表明，建立的渗漏损失改进模型、小水深情况下的糙率加大模型是合理的，反演得到的参数是精确的；由于在水流推进与涨水阶段渠床的非稳定渗漏起了较大作用，所以各渠段的输水能力在非稳定输水阶段比稳定输水阶段稍大。输水能力的计算结果可以为引黄济津未来几年的输水规划与调度提供具体的指导。