运用注意规律提升教学效果

有意注意和无意注意对人完成工作、学习任务有不同的作用,而学生注意品质的好坏将直接影响学习效果。教师只有了解学生的注意特点,遵循注意规律,精心设计教学形式,加强对学生的目的性教育,激发学生的学习兴趣和积极性,培养学生坚强的意志力和良好的注意品质,进而全面提升教学效果。     

机械工程认识实习教学模式的创新与实践

机械工程认识实习足本科生进入专业课程学习之前的一个集中实践教学环节。在分析了过去认识实习教学中存在的问题的基础上,提出了其改革的方向和途径;阐述了机械工程认识实习校内实践教学平台的建设方案和内容。通过组织实施三届大规模的认识实习,验证了校内实践教学平台建设方案的可行性。     

Neuroprotective effect of fasudil combined with bone marrow-derived neural stem cells on mice with experimental autoimmune encephalomyelitis

AIM: To explore the neuroprotective effect of fasudil combined with bone marrow-derived neural stem cells (BM-NSCs) on the mice with experimental autoimmune encephalomyelitis (EAE). METHODS: Female C57BL/6 mice (8~10 weeks old, n=32) were immunized with myelin oligodendrocyte glycoprotein 35-55 (MOG_35-55) to establish chronic EAE model. The mice were randomly divided into control (ddH₂O) group, fasudil group, BM-NSCs group, and fasudil+BM-NSCs group. The clinical score and body weight were recorded every other day. The expression of neurotrophic factors was determined by immunofluorescence staining. RESULTS: In comparison with ddH₂O group, fasudil combined with BM-NSCs delayed onset and ameliorated severity of EAE. The numbers of brain-derived neurotrophic factor, glial cell-derived neurotrophic factor, nerve growth factor, neurotrophin-3 and ciliary neurotrophic factor positive cells in fasudil group, BM-NSCs group and fasudil+BM-NSCs group were all increased in various extents. In particularly, the expression of these neurotrophic factors in fasudil+BM-NSCs group was significantly higher than that in the mice treated with fasudil or BM-NSCs alone (P<0.01). CONCLUSION: Fasudil combined with BM-NSCs promotes the expression of neurotrophic factors and improves microenvironment of central nervous system, thus playing a positive role in neural restoration and regeneration through a synergistic and superimposed effect.     

Calreticulin expression is necessary for protective immune effect of T-cell vaccine in EAE mice

AIM:To study the role of cell membrane ectopic calreticulin (CALR) expression on the protective immunie effect of T-cell vaccine (TCV) on experimental autoimmune encephalomyelitis (EAE). METHODS:EAE model was established by myelin oligodendrocyte glycoprotein 35-55 (MOG_35-55) immunization in C57BL/6 mice, and the mice were immunized with MOG_35-55-specific CALR⁺ and CALR^- T-lymphocytes. Symptomatic scores were compared at the maximum of the disease. On the 15th day after immunization, the proportion of CD4⁺ CD25⁺ Foxp3⁺ regulatory T cells (Treg) in the spleen, and the expression of interferon-γ (IFN-γ), interleukin-4 (IL-4), IL-10 and IL-17A in the serum were measured. RESULTS:Increased expression of CALR in activated T cells after γ-irradiation was observed. Blockade of CALR on the vaccinating T-cell surface reduced the protective effect of TCV. Furthermore, blockade of CALR reduced the number of Treg in the spleen and up-regulated pro-inflammatory cytokines. CONCLUSION:CALR expression in the T cells is necessary for the protective immunity induced by TCV in EAE mice.     

案例式教学在《兽医公共卫生学》课程中的探索与实践

《兽医公共卫生学》是动物医学专业的核心课程之一。为了提高教学质量,提升学生的学习兴趣,适应新型兽医人才培养要求。以《兽医公共卫生学》课程为例,对云南农业大学2届学生进行案例教学的实践与探索。结果表明,案例教学能显著地提高期末卷面成绩,学生对案例教学满意度较高,案例式教学能激发学生学习兴趣、增强学生现场认知感,提高学生综合能力,有利于提升《兽医公共卫生学》教学效果,为课程案例库建设提供依据。     

《动物病理》课程思政课堂教学案例

《动物病理》作为一门重要的专业基础课在畜牧兽医专业开出,在对学生的专业知识和技能进行培养的同时,融入思政元素,培养学生“懂农业,爱农村,爱农民”的从农素养,更好地为国家乡村振兴发展培养专业人才。本文从课程教学案例出发探究课程思政的实施方法与初步成效。     

4LZ—2.0型联合收获机割台模态分析

为建立准确的联合收获机割台有限元模型,获取完备的结构动态特性,进行碧浪4LZ-2.0型联合收获机割台的试验模态分析,利用ModalVIEW软件识别各阶模态参数,同时利用UG软件进行割台有限元模态分析,得到了各阶计算模态,计算了试验模态的MAC值,并通过所测模态数据对比验证了所建立割台有限元模型的正确性.     

中职电工电子技术课程应用互动式教学的实施程序探析

为了适应教育改革的要求,在结合中等职业学生学习的实际情况和电工电子教学的特点,在学习和研究互动式教学理论的基础上,对互动式教学与电工电子教学进行了实践研究,决定在电工电子教学上实行互动式教学模式。     

孔隙结构图像分析中不同试验因素对分析结果的影响

研究了不同试验因素 (包括图像分辨率、土壤切片定向性、分析区域大小等 )对孔隙结构图像分析结果的影响以及试验误差 ,并简要介绍了用于分析土壤孔隙结构的土壤切片及数字图像的制备技术。结果表明 :不同试验因素对分析结果均会产生一定的影响 ,试验误差约在 1 0 %。这表明同一研究中应保持试验条件的相对一致以保证分析结果的可靠性和可比性     

Foraging behaviour and habitat use by Antechinus flavipes and Sminthopsis murina (Marsupialia: Dasyuridae) in response to predation risk in eucalypt woodland

We examined the foraging behaviour and habitat use of two species of small Australian mammal (Antechinus flavipes and Sminthopsis murina) in response to predation risk in remnant eucalypt woodland. Predation risk was manipulated by providing refuge in the form of ground level wire netting to reduce risks from avian and mammalian predators. Giving-up-densities (GUD) using artificial food trays (20 mealworms in 1.5 l vermiculite) quantified the foraging behaviour in response to predation risk, by measuring the quitting harvest rate. Both A. flavipes and S. murina had lower GUDs (number of mealworms remaining) under the netting than in the open, most likely because these areas have lower predation risk. Animals also made greater visits to tracking tunnels under the netting compared to in the open. Tracking animal movements using fluorescent pigments also revealed preference for natural microhabitats that were structurally complex with animals moving most where logs and rock crevices were present. These results suggest that small mammals may use habitat structure to reduce their risks of predation. If future studies are able to demonstrate commensurate population-level responses, manipulation of habitat may be a useful management option to complement the direct control of exotic predators such as foxes and feral cats.