大气气溶胶介电常数的研究

由于气溶胶的介电常数不易直接测量,气溶胶的复折射指数的实部与其介电常数之间存在的一定关系,利用这一关系,可以用气溶胶的复折射指数的实部来求出其介电常数,并对4种基本粒子、3种常见类型的气溶胶以及任意体积比混和建立的气溶胶类型的介电常数进行了研究。     

关于信阳市旅游业发展战略制定的思考

信阳市旅游业近些年来快速发展,旅游业已经成为信阳经济和社会发展的发展的主要 推动力。尤其是在促进就业、增加政府税收、优化产业结构以及对经济的贡献都有不可替代的 作用,但在发展的过程中出现了开发深度不够、文化欠缺等问题。因此,信阳旅游要走发展人 才、科学规划,全域统筹发展、强化品牌带动的发展战略来实现信阳旅游的更好发展,为信阳的 经济和社会发展做出更大的贡献。     

30%噻虫胺·吡唑醚菌酯·苯醚甲环唑悬浮种衣剂的研制 及其在花生田应用的效果

【目的】 评价30%噻虫胺·吡唑醚菌酯·苯醚甲环唑悬浮种衣剂对花生生长的安全性及防治花生土传病害和地下害虫的应用潜力。【方法】 制备30%噻虫胺·吡唑醚菌酯·苯醚甲环唑悬浮种衣剂并测定其pH、黏度、悬浮率及冷热贮稳定性与冷热贮前后的药剂粒度分布变化。在室内,以200、400、800 g a.i./100 kg种子3个剂量进行温室盆栽安全性试验,统计各处理组的出苗时间及播种后14 d花生幼苗的株高、根长、茎叶鲜重、根鲜重与植株干重等生长指标,评价药剂对花生出苗及幼苗生长的安全性。在田间,设置100、200、400 g a.i./100 kg种子3个剂量进行花生种子包衣,以25%噻虫嗪·咯菌腈·精甲霜灵悬浮种衣剂（迈舒平）为对照药剂,进行两年三地的田间药效试验。【结果】 30%噻虫胺·吡唑醚菌酯·苯醚甲环唑悬浮种衣剂达到GB/T17768—1999悬浮种衣剂产品标准。温室盆栽试验中,该药剂以200、400、800 g a.i./100 kg种子对花生出苗及幼苗生长安全。2016年以100、200、400 g a.i./100 kg种子3个剂量进行田间试验,药剂对花生冠腐病的防治效果分别为95.16%、97.98%、98.79%,对花生根腐病的防治效果分别为90.97%、92.26%、92.90%,对花生蚜（Aphis medicaginis）的防治效果分别为79.74%、92.48%、94.13%,且防治效果表现为随药剂剂量的增加而提高。相对于空白对照处理,药剂可以提高花生出苗率10.25%—13.21%,增加花生产量683.75—1 234.12 kg·hm ^-2。由此确定200 g a.i./100 kg种子为田间推荐剂量。2017年使用该剂量,对山东新泰和泰安两地花生冠腐病防治效果分别为81.12%与95.83%,对花生根腐病的防治效果分别为71.74%与92.93%,对地老虎(新泰)与花生茎腐病（泰安）的防治效果分别为93.33%与87.29%。与空白对照相比,在新泰试验中,出苗率提高了4.23%,产量提高了1 146.45 kg·hm ^-2;在泰安试验中,出苗率提高了10.75%,产量提高了1 715.70 kg·hm ^-2。【结论】 研发的30%噻虫胺·吡唑醚菌酯·苯醚甲环唑悬浮种衣剂对花生冠腐病、根腐病、茎腐病及花生蚜、地老虎均有一定的兼治效果,对花生出苗和生长安全并增加花生产量,具有较好的推广前景。     

不同配方蚕沙有机无机复混肥在叶菜类蔬菜上的效果研究

通过盆栽试验,对由蚕沙作为主要有机物料研制的有机无机复混肥的不同配方在生菜和青菜上的施用效果,及其对植株吸收养分和土壤养分供应的影响进行研究。试验结果表明,施用配方1、2、3的蚕沙有机无机复混肥的青菜分别比对照增产35.1%、16.2%、42.1%;生菜增产33.0%、23.4%、38.5%。施用3个配方的蚕沙有机无机复混肥与对照相比,具有促进植株对N、P、K养分吸收的作用,长期施用蚕沙有机无机复混肥对提高和保持土壤养分是有益的。     

响应面试验优化霍山石斛原球茎增殖培养基

为可持续开发霍山石斛资源，采用响应面法优化霍山石斛原球茎增殖培养基。在单因素试验基础上，根据Box Behnken试验设计原理，采用三因素三水平的响应面分析法，以增殖率为响应值进行回归分析。结果表明，萘乙酸（简称NAA）及6 苄氨基嘌呤（简称6 BA）浓度对增殖率影响最为显著，6 BA与马铃薯两者间交互作用显著，适宜的NAA、6 BA及马铃薯浓度分别为0.05 mg·L-1、0.70 mg·L-1和185 g·L-1，此时增殖率为2 989.82%±205.55%，与模型预测值基本符合。响应面法优化霍山石斛原球茎增殖培养基切实可行。     

Assessment of the long‐acting ivermectin formulation in sheep: Further insight into potential pharmacokinetic interactions

The aim of the current study was to evaluate the in vivo pharmacokinetic of ivermectin (IVM) after the administration of a long‐acting (LA) formulation to sheep and its impact on potential drug‐drug interactions. The work included the evaluation of the comparative plasma profiles of IVM administered at a single therapeutic dose (200 μg/kg) and as LA formulation at 630 μg/kg. Additionally, IVM was measured in different gastrointestinal tissues at 15 days posttreatment with both IVM formulations. The impact of the long‐lasting and enhanced IVM exposure on the disposition kinetics of abamectin (ABM) was also assessed. Plasma (IVM and ABM) and gastrointestinal (IVM) concentrations were analyzed by HPLC with fluorescent detection. In plasma, the calculated C_max and AUC_0‐t values of the IVM‐LA formulation were 1.47‐ and 3.35‐fold higher compared with IVM 1% formulation, respectively. The T_1/2ab and T_max collected after administration of the LA formulation were 2‐ and 3.5‐fold longer than those observed after administration of IVM 1% formulation, respectively. Significantly higher IVM concentrations were measured in the intestine mucosal tissues and luminal contents with the LA formulation, and in the liver, the increase was 7‐fold higher than conventional formulation. There was no drug interaction between IVM and ABM after the single administration of ABM at 15 days post‐administration of the IVM LA formulation. The characterization of the kinetic behavior of the LA formulation to sheep and its potential influence on drug‐drug interactions is a further contribution to the field.     

Are complex carcinoma of the feline mammary gland and other invasive mammary carcinoma identical tumours? Comparison of clinicopathologic features,DNA ploidy and follow up

Feline mammary carcinomas are known for their unfavourable prognosis due to a strong tendency to local recurrence and metastasis. We studied 73 spontaneous primary mammary carcinomas and identified eight cases presenting a biphasic nature, with neoplastic epithelial and myoepithelial cells (complex carcinoma). These cases presented histopathologic features associated with a better prognosis; they were also associated with higher overall survival and disease-free survival rates compared to other common invasive mammary carcinomas of non-specified type. Complex carcinoma appears to be a low-grade malignancy.     

新疆棉花病虫害防治药剂剂型研发策略

棉花是我国重要的经济作物,也是受病虫害危害最严重的农作物之一。目前化学防治仍是棉田病虫害防治的重要技术。新疆棉区是我国最大的棉花主产区,气候类型属于典型的温带大陆性气候,具有光照充足、夏季高温干旱、多风、昼夜温差大等特殊气候特点,农药药液喷施过程中容易发生蒸发、飘移、降解等损失,严重影响药剂的防治效果。本文综述了温湿度、风、光照等环境因子对药剂防治效果的影响,以及国内外对提升药剂防治效果采取的调控措施,并结合新疆棉田的特殊气候条件提出了剂型研发的新策略。在提升产品理化稳定性的前提下,还需综合考虑有效成分的理化性质、棉花叶片的结构及润湿特性、施药器械等多种因素。结合农药学、植物保护学、界面化学、有机化学等多学科交叉理论知识指导,利用先进的技术和载体材料研发环境响应型、靶向高效的农药剂型,结合配套使用技术及措施,探索农药高效利用及减量调控途径,为实现农药减量增效、引领棉花产业绿色发展提供科技支撑。