Based on the stochastic medium theory, influence on the surrounding rock and soil by tunnel excavation was studied. formula for predicting movement and deformation of rock and soil mass caused by tunnelling were deduced. And especially for the tunnel with circular arch section, half analytic solution for this problem was put forward. Furthermore, a program was developed to compute the movement and deformation of the rock and soil mass resulted from excavation. The deformation failure criterion of stochastic medium for estimating the surroundings safety was provided and was applied in an engineering example, which proved that the results of the research were reasonable and significant for the tunnel safety construction. 相似文献
A sheep-pox virus strain has been adapted and multiplied in primary lamb kidney cell cultures. The main characteristics of the strain have been verified in vitro after clones were isolated, and the results confirmed its identity. The safety and the potency of the strain have been investigated in sheep.
The inoculation of the strain to sheep was followed by a post-vaccinal reaction materialised by a nodule at the site of inoculation and an increase of temperature by about 1°C. No reactions adversely affecting pregnancy have been noted. Immunisation was demonstrated by an increase in the level of neutralising serous antibodies and protection against the pathogenic virus. The immunity tended to decrease during the second year after primovaccination and a yearly booster vaccination appeared to be necessary. Primovaccination of lambs over 2 months of age produced a better immunity, especially when the lambs were born from vaccinated ewes.
This strain forms the active principle of a freeze-dried vaccine containing no adjuvant of the immunity. 相似文献