Socio-ecological restoration of cultural forests: The case of the Gyeongju historic areas in South Korea

This study seeks to provide a more holistic understanding of traditional forest management. Focusing on cultural/historical sites, this paper highlights the values attributed to historical and cultural landscapes. To restore traditional landscapes and their values, we identified all of the tree species that are currently present in the Oreung royal tomb grove and Gyerim sacred grove in the city of Gyeongju, located in the southeastern area of the Korean peninsula, and compared this to the historical list of species found in these areas by consulting historical documents and old illustrations. The results revealed that a large number of species not part of the original design are present in both the Oreung royal tomb grove (12.51 %) and the Gyerim sacred grove (33.14 %) of the total trees, respectively. Our findings highlight the importance of conserving culturally important species following traditional management strategies to restore historical/cultural landscapes of the past rather than simply increasing biological diversity. This study offers a more comprehensive understanding of the management of traditional forests by incorporating historical and ecological perspectives and suggests future strategies for the conservation of traditional forests.     

卢氏县连翘产业现状及发展对策

本文阐述了卢氏县连翘产业发展的优势和现状，分析了目前产业存在的不足，从选育优良品种、提高连翘非药用价值、规范连翘采摘管理等方面提出了高质量发展连翘产业的建议，以期为当地连翘产业的健康可持续发展提供参考。     

基于网络药理学探讨治疗乳难中药共同代谢通路

基于网络药理学的方法探讨乳难中药共同代谢通路。遴选2020年版《中国药典》中具有下乳或通乳作用的中药材，应用中药系统药理学分析平台(TCMSP)和中国知网筛选中药材的全部活性成分，并使用TCMSP和Swiss Target Prediction分析平台查询相关靶点。借助UniPort数据库进行基因标准化查询。应用GeneCards数据库和OMIM数据库筛选乳难疾病的靶点；通过在线Venny获得药物疾病的共同靶点。将获得的结果导入Cytoscape软件中进行可视化分析，构建PPI网络，筛选核心靶点。采用Metascape数据库对核心靶点进行GO分析和KEGG相关通路富集。共获得有效活性成分58种，潜在靶点336个，疾病靶点2175个，得到共同靶点158个。GO分析得到生物过程947个，细胞组分29个，分子功能54个，KEGG得到IL-17信号通路、肿瘤坏死因子信号通路等119条通路。利用网络药理学分析平台可对治疗乳难中药的有效成分靶点、乳难疾病靶点以及相关信号通路进行预测，为进一步研究探讨乳难中药共同代谢通路提供了重要依据。