免疫抑制对苏拉灭和贝尼尔治疗小鼠伊氏锥虫病疗效的影响

用从自然感染宿主分离的伊氏锥虫原种ＪＧ的克隆ＪＧｍｃ１和ＪＧｍｃ５感染免疫活性正常小鼠和免疫抑制小鼠，２４ｈ后，以苏拉灭或贝尼尔治疗，两种药物对免疫抑制小鼠的ＣＤ１００均明显高于免疫活性正常小鼠，由经受一次苏拉灭或贝尼尔治疗未愈的免疫抑制小鼠分离的锥虫，感染免疫活性正常小鼠，再用原来对该克隆感染的免疫活性正常小鼠ＣＤ１００的苏拉灭或贝尼尔治疗即无效。用免疫溶解试验分别测定一组免疫抑制和免疫活性正确     

Courses for horses: Rethinking the use of proton pump inhibitors in the treatment of equine gastric ulcer syndrome

Oral omeprazole has been the cornerstone of equine gastric ulcer syndrome (EGUS) treatment for nearly 20 years. However, approximately 15–30% of equine squamous gastric disease (ESGD) cases and 75% of equine glandular gastric disease (EGGD) cases fail to heal within current treatment guidelines. Recently, a number of factors that may affect the efficacy of oral omeprazole have been highlighted and the pharmacodynamics of a number of novel proton pump inhibitors (PPIs) have been described in the horse. The purpose of this article is to review the factors that affect oral omeprazole efficacy, with the goal of maximising therapeutic response, and the novel PPIs recently described.     

Influence of Land-Use Legacies Following Shrub Reduction and Seeding of Big Sagebrush Sites

Big sagebrush (Artemisia tridentata Nutt.) plant communities often require management to reduce shrub density and rehabilitate understory vegetation. We studied vegetation responses to a two-way chain harrow treatment and broadcast seeding of 12 herbaceous species at eight Wyoming big sagebrush (A. tridentata Nutt. subsp. wyomingensis Beetle & Young) sites. These sites differed in land-use history; five were cultivated for dryland wheat production during the 1950 ? 1980s and then seeded with introduced forage grasses (C-S), while three had not been exposed to this land-use legacy (non C-S). Our objective was to evaluate whether the C-S legacy influences the magnitude of vegetation change following contemporary treatment. Before treatment, C-S sites had lower sagebrush cover, higher dead sagebrush cover, and higher broom snakeweed (Gutierrezia sarothrae [Pursh] Britton & Rusby) cover than adjacent non C-S sites. Plant community change 3 years after treatment, determined with multivariate ordination analysis of species composition, varied between site histories, and response to treatment was most strongly correlated with reductions in sagebrush cover, increases in perennial grasses, and increases in 10 other herbaceous species—including some undesirable species and four that were seeded in 2010. Five years after treatment, mature sagebrush cover remained reduced for both land-use histories, yet density of sagebrush seedlings and broom snakeweed increased in C-S sites during the second and third years after treatment. In addition, perennial forb cover increased for C-S sites, while perennial grass biomass increased for non C-S sites. Our results emphasize that broad variability in plant community responses to sagebrush reduction and seeding is possible within the same ecological site classification and that legacy effects due to the combination of past cultivation and seeding should be considered when planning restoration projects, including the consideration that seeding may not always be necessary on C-S sites.     

禽流感病毒分子生物学的研究进展

禽流行性感冒(av ian in fluenza,A I,简称禽流感)是由A型禽流感病毒(av ian in fluenza v irus,A IV)引起的禽类烈性传染病。作为被世界动物卫生组织(O IE)定为A类的传染病,A I不仅给世界养禽业造成了巨大的经济损失,而且对人类健康和生命安全构成了严重威胁。因此,A I已经成为人们关注的焦点,国内外学者也对其进行了大量研究。作者从病原基因组及其编码的蛋白质、致病力、变异性以及对人类感染A IV的分子机制等角度就A IV的分子生物学研究作一综述,为防制A I提供理论基础,并在此基础上探讨了人类禽流感的防治措施,加深人们对A I的认识。     

中草药“杀虫补”防治鸡球虫病实验研究

中药"杀虫补"以杀虫燥湿、清热解毒遣药组方,主要由攻毒杀虫、去腐敛疮类药组成。实验结果表明,1%"杀虫补"组ACI为181.7,相对增重率达88.7%;0.5%"杀虫补"组ACI为173.4,相对增重率达82.4%;磺胺氯吡嗪钠组ACI为173.5,相对增重率达80.5%,表明"杀虫补"治疗鸡球虫病的效果确切,1%治疗剂量属高效杀虫药。用5%和10%剂量进行慢性毒性实验,未发现明显的中毒反应,但平均增重率分别为43.1%和32.0%,增重效果明显受到影响(P0.01),说明长期大剂量使用,会造成鸡的生长抑制。5 g/kg和3 g/kg剂量急性毒性实验表明,大剂量一次性使用不会造成鸡的死亡,但会抑制鸡的生长。以上实验结果表明,该中药组方对肉鸡球虫病具有治疗、预防以及增重的效果,按治疗剂量使用安全有效。     

青海省祁连县羊布鲁氏病发生情况调查及防治

羊布鲁氏杆菌病俗称布病,是由布鲁氏杆菌感染引起的一种人畜共患病。近年,我国家畜饲养量不断增加,动物及其产品流通不断频繁,部分地区布鲁氏杆菌病呈现上升趋势,严重威胁当地畜牧养殖产业和人民群众的身体健康。该文主要就祁连县羊布鲁氏杆菌病的发生情况进行调查,提出相应的防治对策。     

猪场废弃物处理技术与应用

养殖废弃物对环境的污染越来越严重,为保证养殖与环境协调发展,我国开展养殖废弃物综合利用方式的研究。近年,各地开发出多种废弃物处理和利用方式,主要是以循环发展理念为技术发展方向,提高废弃物循环利用效率。该文列举国内外的养殖废弃物处理技术,结合我国生猪养殖现状,总结出适合我国的生猪养殖废弃物高效利用技术。     

羊传染性脓疮皮炎治疗

羊传染性脓痂皮炎又被称为羊传染性脓疱病、羊口疮病,是由羊传染性脓疱病毒感染引发的一种急性接触性传染性疾病。羊养殖主产区均有发生,是一种常见疾病。羊传染性脓痂皮炎虽然造成的死亡率较低,但是会严重影响羊群正常采食,造成营养物质供给不足,身体逐渐消瘦,抵抗能力变差,易继发感染多种传染性疾病,表现出复杂的临床症状,威胁羊群健康。     

牛出血性败血症诊断与防治

牛出血性败血症具有致病因素多、传染源多、危害大的特点,养殖户要针对该病的特点制定有效防控方案,并严格执行防控措施,定期对牛群给予免疫注射,并加强饲养管理,才能有效降低发病几率,提升经济效益。该文主要论述牛出血性败血症的诊断与防治。