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褪黑素是一种广泛存在于动物体内的激素,不仅能够调节动物昼夜节律,还能够从多方面影响动物的繁殖性能,对于季节性繁殖动物,褪黑素根据日照时长的变化表现出抑制或促进繁殖性能的作用。对于幼年动物,褪黑素表现出抑制发情的作用,体成熟后则表现促进发情的作用。褪黑素主要通过下丘脑-垂体-性腺轴调控动物繁殖活动,除此之外,褪黑素还能够直接作用于生殖系统甚至早期胚胎,通过提高组织及细胞抗炎及抗氧化功能来改善动物繁殖性能。目前,褪黑素能够用于治疗精神疾病及炎症、促进畜禽繁殖和调节昼夜节律,是相关研究领域的热门话题。本文详细描述了褪黑素的生物合成以及分泌调控,并结合褪黑素的生理功能,阐述了对动物繁殖性能以及辅助生殖的影响。 相似文献
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Stine Jacobsen 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2023,52(Z1):8-18
Serum amyloid A (SAA) has become an indispensable part of the management of equine patients in general practice and specialized hospital settings. Although several proteins possess acute phase properties in horses, the usefulness of SAA exceeds that of other acute phase proteins. This is due to the highly desirable kinetics of the equine SAA response. SAA concentrations exhibit a rapid and pronounced increase in response to inflammation and a rapid decline after the resolution of inflammation. This facilitates the detection of inflammatory disease and real-time monitoring of inflammatory activity. SAA may be used in all stages of patient management: (1) before diagnosis (to rule in/rule out inflammatory disease), (2) at the time of diagnosis (to assess the severity of inflammation and assist in prognostication), and (3) after diagnosis (to monitor changes in inflammatory activity in response to therapy, with relapse of disease, or with infectious/inflammatory complications). By assessing other acute phase reactants in addition to SAA, clinicians can succinctly stage inflammation. White blood cell counts and serum iron concentration change within hours of an inflammatory insult, SAA within a day, and fibrinogen within 2–3 days; the interrelationship of these markers thus indicates the duration and activity of the inflammatory condition. Much research on the equine SAA response and clinical use has been conducted in the last decade. This is the prerequisite for the evidence-based use of this analyte. However, still today, most published studies involve a fairly low number of horses. To obtain solid evidence for use of SAA, future studies should be designed with larger sample sizes. 相似文献
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Novel surface treatment technique by silane film is developing for metallic anti corrosion and coat improvement. The key points, hydrolysis and condensation, for the stability of the Silane agent(SA) solution is investigated, and the effective factors of stability for silane agent solution and the relative rule are discussed. It is found that stability of SA solution is related to the temperature, pH, solvents, SA concentration and additive by studying the state of the solution and the conductivity-time curve of SA solution. Meanwhile, controlling factors and improving methods for SA stability are proposed to guide the practical application of metallic surface anti-corrosion treatment by SA. 相似文献
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A Coptis Chinesis is the dry rhizoma of ranunculaceous Coptis Chinesis Franch or Coptis deltoidea C. 7. Cheng et Hisao, or Coptis teeta Wall. It is the traditional Chinese herb, which is used in the contagious diseases. In recent years, its new pharmacological actions have been reported, which are antitumour, hypoglycemic response, immunoloregulation, improving the functions of cardiovascular. The important pharmacological functions of Coptis Chinesis are hypoglycemic response, improving the functions of cardiovascular, antitumour. With the deeply researching of Coptis Chinesis pharmacology, and the continuous founding of pharmacological mechanism, new preparation will be widely applied in the clinic. 相似文献
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An equivalent model for hollowing-center grounding device is proposed, the hollowing-center grounding device resistance is calculated with the surface charge simulation method and the computer programme is programmed based on this model. The accuracy of the model and method is validated by experimentation. 相似文献
100.
A theoretical model is developed for the dropwise condensation heat transfer on the horizontal circular surface with radial gradient surface energy based on the heat transfer model of individual condensate drop and the size distribution model of condensate drop on homogeneous condensation surface.The effect of variation of contact angle on the gradient surface on condensation heat transfer and condensate drop size distribution is taken account of in this model.The theoretical calculation method was obtained to predict the dropwise condensation heat transfer coefficient on the horizontal circular surface with radial gradient surface energy under various wall subcooled temperature,contact angle profile on wall surface,and working fluid.The effects of surface energy gradient,wall subcooled temperature,and thermophysical properties of condensate on the condensation heat transfer are discussed respectively.The calculation results show that the condensation heat transfer coefficient increases slightly with the increase of wall subcooled temperature.As latent heat and surface tension increasing,the condensation heat transfer coefficient increases.A larger surface energy gradient induces a larger condensation heat transfer coefficient. 相似文献