Magnetic resonance (MR) images may be useful for radiation planning due to greater contrast resolution. One disadvantage of MR images for radiation planning is the inability to incorporate electron density information into the dose calculation algorithm. To assess the magnitude of this problem, we evaluated radiation dose distribution in canine brain by comparing computed tomography (CT)-based radiotherapy plans with and without electron density correction. Computerized radiotherapy plans were generated for 13 dogs with brain tumors using 6 MV photons. A tissue-contouring program was used to outline the gross tumor volume (GTV) and the planning target volume (PTV) for each patient. Two treatment plans were generated for each dog. First, the plan was optimized without heterogeneity correction. Then the heterogeneity correction was implemented without changing any other plan parameters. Isodose distributions and dose volume histograms (DVHs) were used to compare the two plans. The D95 (dose delivered to 95% of the volume) within the PTV was calculated for each treatment plan and differences in the D95s were compared. The mean D95s without and with heterogeneity correction were 49.1 +/- 0.7 and 48.9 +/- 1.0Gy, respectively. The absolute mean percent dose difference without and with heterogeneity correction was 1.0 - 0.9% (-1.3-3.2%) and was not considered to be clinically significant. We found no clinically significant difference between CT-based radiotherapy plans without and with heterogeneity correction for brain tumors in small animals, which supports the use of MR-based treatment planning for radiotherapy of small animal brain tumors. 相似文献
Efforts at mitigating global biodiversity loss have often focused on preserving large, intact natural habitats. However, preserving biodiversity should also be an important goal in the urban environment, especially in highly urbanized areas where little natural habitat remains. Increasingly, research at the city/county scale as well as at the landscape scale reveals that urban areas can contain relatively high levels of biodiversity. Important percentages of species found in the surrounding natural habitat, including endangered species, have been found in the urban forest.
This contribution concisely highlights some examples of urban biodiversity research from various areas of the world. Key issues involved in understanding the patterns and processes that affect urban biodiversity, such as the urban–rural gradient and biotic homogenization, are addressed. The potential for urban areas to harbor considerable amounts of biodiversity needs to be recognized by city planners and urban foresters so that management practices that preserve and promote that diversity can be pursued. Management options should focus on increasing biodiversity in all aspects of the urban forest, from street trees to urban parks and woodlots. 相似文献
Sustainable development requires, among other things, that development projects not result in the degradation of natural resources for outdoor recreation. There has been a rapid increase in knowledge regarding the importance of the external environment to our health and well-being. Stress is reduced significantly when people are exposed to health-promoting nature and landscape values. Many people are actively choosing to reduce their stress. Doctors today prescribe outdoor walks in peaceful environments for the same purpose. A high level of traffic noise increases stress. This paper discusses the application of silent values in an infrastructure development project, the extension of Sturup Airport, east of Malmö, Sweden and Copenhagen, Denmark. Through estimating the change in noise resulting from the development, it is possible to integrate mitigating and compensating measures in the planning process discussions. Such measures can be negotiated as conditions for authorization of the project. The airport is situated in an area rich in nature values for recreation. The airport expansion will mean both new noise impacting "silent" areas and increasing noise levels in already noise-affected areas. In this study, we have taken a positive stand on the silent areas, mostly agriculture land, where compensation measures could be taken, thus balancing the loss of silent nature values for recreation. Silent areas that will not be affected are suitable and feassible for compensation measures thus can be called compensation areas. In this way the development of new recreational areas, preferably designed as urban forests, are critical preconditions for the negotiations for the airport extension. The conclusion is that urban forest investments for health and well-being can be an important part of strategic decisions in spatial planning. As preconditions for a permit, the development and financing of new urban forests and green areas can be part of the total development plan. This is an issue of global interest, as many countries are in a process of rapid urbanization, and urban greening and urban forestry have an important role to play in the process of promoting quality of life and improving environmental quality. 相似文献