Membrane Action in Full Width X-joints SHS Loadedwith In-plane Bending Moments

Based on 'yielding-line' method, in this paper, the static strength of X-joints, SHS loaded with in-plane bending moments is analyzed and two static strength formulas are derived: one considers the membrane action and the another not. This paper can be helpful to researchers of tubular structures.     

兽用非甾体类抗炎药美洛昔康研究现状

美洛昔康作为非甾体类抗炎药(NSAIDs),不仅可广泛用于抗炎、镇痛、解热,还具有安全高效、副作用小、半衰期长等优点。研究显示,此药具有较好的抗炎及解热镇痛作用,无毒或低毒性,在美国已广泛应用于犬、猫等宠物临床疾病治疗。由于目前兽用美洛昔康剂型较为单一,且临床应用靶动物种类较少,因此未来需开发更多种类剂型,同时应增加不同靶动物的临床应用研究。本文对兽用美洛昔康的理化性质、作用机理、药理作用、药代动力学、不良反应和临床应用等方面的研究进行综述,旨在为开发新型的兽用美洛昔康及其临床安全、合理用药提供参考。     

Effect of drug-containing serum of Fushen Jiangzhuo formula on anti-fibrosis factors HGF and BMP-7 in rat renal interstitial fibroblasts with renal tubulointerstitial lesion

AIM: To study the protective effects and mechanism of Fushen Jiangzhuo formula (FSJZ) on the rat renal interstitial fibroblasts with renal tubulointerstitial lesion. METHODS: The serum containing FSJZ and blank control serum were prepared. The rat model of mesangial proliferative glomerulonephritis (MsPGN) was established and extended the time of modeling to 20th weeks for developing tubulointerstitial lesion naturally. The rat renal interstitial fibroblasts at the end of 12, 16, 20 week of modeling were isolated and cultured. The effects of FSJZ on the expression of hepatocyte growth factor (HGF) and bone morphogenetic protein-7 (BMP-7) at mRNA and protein levels in the pathological renal interstitial fibroblasts were determined. RESULTS: The anti-fibrosis factors HGF and BMP-7 were changed in pathological renal interstitial fibroblasts. Renal tubulointerstitial lesion significantly down-regulated the expression of HGF and BMP-7, while the drug containing serum of FSJZ significantly up-regulated the expression of HGF and BMP-7. CONCLUSION: Drug containing serum of FSJZ has protective effect on pathological renal interstitial fibroblasts by regulating the mRNA and protein expression of HGF and BMP-7.     

外泌体的生物学功能及其在动物遗传育种中的应用

外泌体是一种广泛存在于多种细胞间质中的囊泡,多种细胞在正常情况下或在细胞外刺激等应激条件下都能产生外泌体,来自不同细胞类型的外泌体作用机制及功能有很大区别。外泌体可通过膜蛋白与靶细胞膜蛋白结合、膜蛋白碎片与细胞膜上受体结合、膜与靶细胞膜直接融合等方式传递生物活性分子,从而参与机体免疫、细胞分化等过程。由于外泌体具有来源天然、穿越屏障能力好、生物相容性强等特点,在许多研究领域均受到广泛的关注。作者介绍了外泌体的形态特点、形成过程、作用机制、分离纯化、生物学特性、功能及应用;总结了近年来外泌体在畜禽研究中的应用。外泌体不仅可应用于动物遗传育种中,还可作为工具或载体来研究动物体内各种生化途径。该综述可为外泌体的相关研究及应用提供参考。     

Genetic analysis of resistance to Fusarium wilt disease,yield and yield-related traits of pigeonpea (Cajanus Cajan (L.) Millsp.)

ABSTRACT

Understanding the genetic control of Fusarium wilt resistance is crucial in pigeonpea breeding programme. This study aimed to study the gene action controlling Fusarium wilt resistance, yield and yield components and select promising crosses possessing resistance to Fusarium wilt along with important agronomic yield traits. Six lines were crossed with four testers in a line x tester mating design. For Fusarium wilt reaction, F₁’s progenies were evaluated in a sick field having inoculums of Fusarium wilt at one location for two seasons and in a pot as well. The F₁’s and parents were evaluated for yield and yield components at two locations for two seasons using a row-column design with two replications. Results indicated that parents and crosses had highly significantly difference for yield and important agronomic traits. General combining ability (GCA) effects of lines and testers were also significant. Specific combining ability (SCA) was also significant for some crosses. Non-additive gene action was more important than additive gene action except for days to maturity and plant height. Crosses ICEAP 00932?×?TZA 2439 and ICEAP 00932?×?TZA 197 displayed small effects of SCA for Fusarium wilt and large SCA for most of yield traits and should be used for integrated disease management.     

粪肥堆腐中尿囊素含量变化及添加物对其变化的影响

研究粪肥堆腐过程中尿囊素 ( All)含量变化表明 :4种粪肥的变化趋势相同即呈抛物线型 ,但变化的速度不同。加入含氮添加物能显著提高粪肥中 All的含量 ,并在堆腐后期能减缓All的下降速率。研究还表明 ,蛋白质和核酸的变化对 All的含量也有影响 ,通径分析结果 ,蛋白质对 All的累积直接贡献大 ,核酸的直接作用较小 ,两者的间接作用都小     

氯化钠胁迫下蓝藻Anabaena 7120对氧的敏感性和氢的保护作用

正常培养液中NaCl浓度增高时,蓝藻固氮活性下降,对氧的敏感度增大,氧浓度愈高,敏感度愈大。分子氢可以削弱或消除氧对固氮酶活性的抑制,其良好效应主要表现在固氮反应初期。 添加光合抑制剂、CO_2、N_2,以及在厌氧条件下,氢对NaCl胁迫下受氧伤害蓝藻固氮酶活性的保护效应低于对正常生长蓝藻的保护效应。     

药用植物太子参的研究进展

介绍了太子参的化学成分、药理作用、临床应用功效特点及在化妆品、保健营养中应用的研究进展及生产现状,并指出太子参生产利用中存在的问题和对策.     

4种植物性物质对几种仓库害虫驱避性的估价

选用４种易于取得的中草药、香料和食用油，分别对玉米象、赤似谷盗和绿豆象的驱避性进行了试验，结果表明：山柰、黑胡椒、米糠油对玉米象成虫、赤拟谷盗幼虫和绿豆象成虫及八角对玉米象成虫、赤拟谷盗幼虫都有明显驱避作用，其中山柰的驱避作用最强。当按０．３ｍｌ·皿（－１）的浓度拌小麦和绿豆时，处理４８ｈ，山柰对玉米象和绿豆象的驱避率高达１００％；黑胡椒对玉米象的驱避率为８６％；对绿豆象为８０．５％；八角对玉米象的驱避率为７８．２％。用滤纸法处理７２ｈ，山柰、八角、黑胡椒、米糠油对赤拟谷盗幼虫的驱避率依次为９４．７％、８４．３％、５０．１％和３３．２％。