Canine oral melanoma

Melanoma is the most common oral malignancy in the dog. Oral and/or mucosal melanoma has been routinely considered an extremely malignant tumor with a high degree of local invasiveness and high metastatic propensity. Primary tumor size has been found to be extremely prognostic. The World Health Organization staging scheme for dogs with oral melanoma is based on size, with stage I = <2-cm-diameter tumor, stage II = 2- to <4-cm-diameter tumor, stage III = > or = 4cm tumor and/or lymph node metastasis, and stage IV = distant metastasis. Median survival times for dogs with oral melanoma treated with surgery are approximately 17 to 18, 5 to 6, and 3 months with stage I, II, and III disease, respectively. Significant negative prognostic factors include stage, size, evidence of metastasis, and a variety of histologic criteria. Standardized treatments such as surgery, coarse-fractionation radiation therapy, and chemotherapy have afforded minimal to modest stage-dependent clinical benefits and death is usually due to systemic metastasis. Numerous immunotherapeutic strategies have been employed to date with limited clinical efficacy; however, the use of xenogeneic DNA vaccines may represent a leap forward in clinical efficacy. Oral melanoma is a spontaneous syngeneic cancer occurring in outbred, immunocompetent dogs and appears to be a more clinically faithful therapeutic model for human melanoma; further use of canine melanoma as a therapeutic model for human melanoma is strongly encouraged. In addition, the development of an expanded but clinically relevant staging system incorporating the aforementioned prognostic factors is also strongly encouraged.     

三江源区退化高寒草甸蒸散的变化特征

为揭示三江源区退化高寒草甸水分收支变化特征,利用涡度相关和微气象方法对青海省果洛州大武镇退化高寒草甸生态系统的年蒸散变化进行了定量研究,并探讨了环境和生物因子对其影响。结果表明:年总蒸散量为481.9mm,年蒸散量约占年降水量的97%。生长季中日均蒸散量为2.3mm·d-1,而非生长季日均蒸散量仅为0.6mm·d-1。温度与蒸散量呈明显的指数关系;该区接收的太阳辐射较强,但净辐射占太阳辐射的比例相对较低(46%),在非冻土时期,蒸散量与净辐射呈线性关系;研究区降水量相对丰沛,与温度和净辐射相比,土壤含水量对蒸散的影响相对较小。本研究说明高寒草甸的退化加剧了生态系统的蒸散量,从而降低了生态系统涵养水分的能力,净辐射和温度是驱动三江源区退化高寒草甸生态系统蒸散最主要的环境因子。     

RADIATION PNEUMONITIS IN THREE DOGS

Radiation pneumonitis developed within the radiation treatment field in three dogs with soft tissue sarcomas located on or adjacent to the thoracic wall. Radiographic signs compatible with a diagnosis of radiation pneumonitis developed from one (n = 2 dogs) to two (n = 1 dog) months after completion of therapy. The initial radiographic sign was an alveolar infiltrate in all three dogs. At subsequent examinations at variable time periods after treatment, radiographic findings included: bronchiectasis (n = 3 dogs), alveolar infiltrate (n = 2 dogs), decreased lung volume (n = 2 dogs), and unstructured interstitial opacification (n = 1 dog). Necropsy examination of one dog at fourteen months after the completion of radiotherapy showed evidence of pulmonary fibrosis within the irradiated lung. Necropsy examination of the second dog did not show any evidence of radiation induced changes. It is possible that histopathologic examination did not include irradiated lung. No clinical signs that could be attributed to the radiation pneumonitis were observed in any dog. It appears that approximately 25% of the lung can be safely irradiated to high doses, if indicated, in order to deliver an adequate dose of radiation to a primary tumor site.     

Energy metabolism and apoptotic effect of microwave radiation on rat myocardial cells

AIM: To investigate the effect of microwave radiation at different intensities on the rat myocardium and its possible mechanism.METHODS: The rats were radiated by the intensity of 500, 1 000, 1 500 and 2 000 W/m² with 2 450 MHz microwave for 6 min. The heart tissue was collected 6 h after microwave radiation. ATP and mitochondria complex Ⅳ and Ⅴ were measured. The changes of the tissue structures were observed under transmission electron microscope. The apoptosis of the myocardial cells was detected by a cell analyzer. The protein level of cleaved caspase-3 was determined by Western blotting.RESULTS: The concentration of ATP and activity of mitochondria complex Ⅳand Ⅴ signi-ficantly decreased compared with control group in the cardiac tissues. The decreased number, morphological abnormalities such as dissolved cavitation, matrix and obvious tumefaction of mitochondria were observed under transmission electron microscope. The microwave radiation induced the apoptosis of myocardial cells in the rats. The cell apoptotic rate and the protein level of cleaved caspase-3 increased with increasing intensity of microwave radiation(P<0.05).CONCLUSION: Microwave radiation has obvious injury effect on the rat heart, which can cause cardiac energy metabolism dysregulation and cardiac myocyte apoptosis.     

内外遮阳对连栋塑料温室内光环境的影响

借助热辐射理论 ,在分析太阳辐射在温室内的传播过程基础上 ,建立了一种连栋塑料温室在无遮阳、内遮阳和外遮阳情况下的光环境模型 ,并结合实际情况分析讨论了边缘效应对室内光环境的影响。结果表明 :在不考虑边缘效应时 ,内、外遮阳条件下温室内的光环境基本上无差异 ;而考虑边缘效应时 ,外遮阳具有相对较好的光照环境 ,在遮阳网透射率低时更为明显。实测结果与模拟值的变化规律基本吻合。     

基于光合有效辐射瞬时值估算日均值的方法

光合有效辐射是太阳辐射的一部分,是植被进行光合作用和陆地生态系统碳循环的核心因素,对估算植被生产力具有重要影响。本文基于SURFRAD多年观测数据,建立了一个线性回归模型,由上午、下午瞬时光合有效辐射值估算日均值。该模型模拟效果较好,单个观测站的均方误差低于9 W·m^-2,判定系数不低于0.96,并适用于不同经纬度、气候条件和海拔高度下的区域,总的均方误差为8.863 1 W·m^-2,判定系数R2为0.977,表明该模型和方法有较好的可行性和可靠性。     

籼型恢复系郴R92-225的杂交和辐射选育及应用

本文介绍了籼型恢复系郴R92-225的杂交和辐射选育过程、特征特性及配制杂交组合应用于生产的情况。对选育的郴R92-225的有利变异和选育方法及应用进行了讨论。     

淀粉高吸水剂微波辐射合成研究

以N,N’-亚甲基双丙烯酰胺为交联剂,过硫酸钾为引发剂,丙烯酸为淀粉接枝单体,采用微波技术合成淀粉高吸水剂。并用FTIR对产物结构进行了表征。实验结果表明,微波技术合成淀粉高吸水剂,具有节能、省时、高效,工艺简单的显著特点,具有生物可降解性,产物吸水速率明显高于传统化学法,是值得推广的清洁生产工艺。     

Critical period for grain number establishment of near isogenic lines of two- and six-rowed barley

In barley no studies have attempted to pinpoint the critical period for grain number determination, and it is frequently stated that the critical period is similar to that of wheat. However, there are important differences between the species and among barley genotypes (i.e. two- and six-rowed types) suggesting that this assumption requires testing. The objectives of this paper were (i) to determine the critical period for grain number determination in two- and six-rowed barleys, and (ii) to identify which yield components were more sensitive to changes in incident radiation during that period.

Two field experiments were conducted using two pairs of near isogenic lines differing only in the spike type. Shading was imposed at different periods throughout the crop cycle (from 60 days before heading to 15 days after) to reduce incident solar radiation approximately 70%.

The critical period for grain number determination tended to be slightly earlier in two- (ca. between 40 and 10 days before heading) than in six-rowed barleys (ca. between 30 days before heading until that stage). In terms of the external phenology, the beginning of the critical period for setting grains was 10 days after the beginning of stem elongation, and 10 days before flag leaf appearance in two- and six-rowed lines, respectively. Changes in the number of grains per unit area were correlated with crop growth rate during the critical period for yield determination.