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Jinglong LI Peng ZHANG Hongju LIU Wei REN Jinjing SONG Elizabeth RAO Eiki TAKAHASHI Ying ZHOU Weidong LI Xiaoping CHEN 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(10):1235-1240
Iron is involved in various physiological processes of the human body to maintain normalfunctions. Abnormal iron accumulation in brain has been reported as a pathogenesis ofseveral neurodegenerative disorders and cognitive impairments. Hemojuvelin (HVJ) is amembrane-bound and soluble protein in mammals that is responsible for the iron overloadcondition known as juvenile hemochromatosis. Although iron accumulation in brain has beenrelated to neurodegenerative diseases, it remains unknown the effect of mutation of HVJgene on cognitive performance. In our studies, HJV(−/−) mice showed deficits in novelobject recognition and Morris water maze tests. Furthermore, the expression ration ofapoptotic marker Bax and anti-apoptotic marker Bcl-2 in the hippocampus and prefrontalcortex showed higher levels in HJV(−/−) mice. Our results suggested that deletion of HJVgene could increase apoptosis in brain which might contribute to learning and memorydeficits in mutant mice. These results indicated that HJV(−/−) mice would be a usefulmodel to study cognitive impairment induced by iron overload in brain. 相似文献
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兽医微生物学是动物医学本科课程体系中的一门专业基础课,涉及内容广,知识更新快。有限的课堂时间无法满足学生对学科前沿知识的学习期待,传统填鸭式的教学模式不能有效发挥学生的主动性,从而影响教学质量的提高。基于智能手机的碎片化移动微学习,由于迎合了娱乐式学习和终身学习的需求,目前已广泛应用于外语类文科课程的教学过程中,但在微生物学等非文科类专业尚未全面推广。介绍了碎片化移动微学习的概念和研究现状,分析了其在兽医微生物学教学中的应用,以期为相关学科的教学改革提供参考。 相似文献
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Keyvan Karami Saeed Zerehdaran Ali Javadmanesh Mohammad Mahdi Shariati Hossien Fallahi 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2019,136(3):205-216
Imprinted genes display biased expression of paternal and maternal alleles in mammals. They are marked through epigenetic process during gametogenesis. Characterization of imprinted genes has expanded our understanding of the regulation and function of genes. In the current study, 22 experimentally validated imprinted genes in bovine (Bos Taurus) were analysed. Several supervised machine learning algorithms and attribute weighting methods were used to find characteristics of different types of imprinted genes and suggest a classification method for finding maternally and paternally expressed genes in bovine. For assessing the best model and comparing attributes in other organisms, we have also conducted a comparative analysis for human and sheep imprinted genes. According to the results of the present study, GC contents 10 and 100 kb upstream, Gly and Gln amino acids, Ile/ATC codon usage, LINE and SINE in 100kbup and length of first intron were significantly different between the maternal and paternal genes in cattle. Considering all species together, we found that GC content 100 kb up, LINE 100 kb up and the frequency of amino acids like Gly, Gln and Met were the most important attributes for identifying the paternal and maternal imprinted genes. These findings could imply conservation pattern in the attributes among these species. 相似文献
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在多年的实践经验的基础上,重点介绍了以牛阴道开膣器输精的技术要点,主要为选定最佳的输精时间、严格技术操作规范、做好母牛早期妊娠诊断工作等。 相似文献
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朱真莉 《四川畜牧兽医学院学报》2007,5(6):182-185
高等学校举办干部教育培训,主要依靠普通高等教育的教师,特色鲜明,优势明显,但也存在一些问题。教师是教育质量的保障,提高高等学校干部教育工作的质量,就必须抓好教师队伍的建设,以增强干部教育的生命力。 相似文献
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A. V. Vasileva E. V. Gorbunova A. S. Vasilev V. S. Peretyagin A. N. Chertov V. V. Korotaev 《British poultry science》2018,59(6):636-645
ABSTRACT1. The objective of this study was to develop a machine vision method for analysing exterior parameters of chicken eggs to automate the stage of primary sorting.2. The developed algorithm based on predetermined thresholds calculated egg quality indicators, including geometric dimensions, shape index and the mottling grade. The algorithm was implemented with an experimental setup that combined the image-based and the candling methods. A total of 400 egg samples were analysed.3. Comparison of results of the algorithm with those obtained using the traditional manual method showed that mean value of radii values difference was 0.095 ± 0.058 mm for the sharp and 0.080 ± 0.047 mm for the blunt end of the egg, with standard deviations of 0.58 mm and 0.49 mm, respectively.4. The correlation coefficient between the shape index values determined by the two methods was 0.93; the standard deviation of absolute differences between corresponding values was 1.05%.5. The results of mottling grade estimation were compared using F-measure and confusion matrix.6. The results allow the possibility to perform the assessment of egg exterior quality factors in an automatic mode, independent of the expertise of a grader. 相似文献
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南方优质米加工易碎,成本高,不利企业竞争。针对优质米生产加工中易产生碎米的原因,可从稻谷的品种、栽培、收购、储存、加工工艺和设备优化等方面入手,采取有效措施降低碎米率。 相似文献