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Tomoaki ONODA Ryuta YAMAMOTO Kyohei SAWAMURA Harutaka MURASE Yasuo NAMBO Yoshinobu INOUE Akira MATSUI Takeshi MIYAKE Nobuhiro HIRAI 《Journal of Equine Science》2013,24(4):63-69
Percentile growth curves are often used as a clinical indicator to evaluate variations of
children’s growth status. In this study, we propose empirical percentile growth curves
using Z-scores adapted for Japanese Thoroughbred horses, with considerations of the
seasonal compensatory growth that is a typical characteristic of seasonal breeding
animals. We previously developed new growth curve equations for Japanese Thoroughbreds
adjusting for compensatory growth. Individual horses and residual effects were included as
random effects in the growth curve equation model and their variance components were
estimated. Based on the Z-scores of the estimated variance components, empirical
percentile growth curves were constructed. A total of 5,594 and 5,680 body weight and age
measurements of male and female Thoroughbreds, respectively, and 3,770 withers height and
age measurements were used in the analyses. The developed empirical percentile growth
curves using Z-scores are computationally feasible and useful for monitoring individual
growth parameters of body weight and withers height of young Thoroughbred horses,
especially during compensatory growth periods. 相似文献
13.
Takamitsu TSUKAHARA Eriko KISHINO Ryo INOUE Nobuo NAKANISHI Keizo NAKAYAMA Tetsuya ITO Kazunari USHIDA 《Animal Science Journal》2013,84(1):54-59
Early weaning induces villous atrophy in the small intestine. Reduction in villous height in the small intestine after weaning is associated with reductions in brush‐border enzyme activity. Body weight gain after weaning is, therefore, correlated with villous height. This evidence suggested that the maintenance of small intestinal structure and function after weaning is important for the growth of young pigs. On the other hand, the relationship between villous height and the activity of the digestive enzymes in the small intestine has not been studied with piglets from the suckling to the growing period. Five suckling piglets, four piglets in the proximal stage of weaning, four pigs in the distal stage of weaning and four growing pigs were used. The activities of lactase (LA), sucrase (SA) and maltase (MA) were determined. LA showed a positive correlation with villous height in weaning. SA and MA were positively correlated with villous height from suckling to growing. In a previous study, non‐infectious dyspeptic diarrhea was frequently observed in growing piglets on Japanese swine farms. The maintenance of villous height to retain disaccharidase activity may prevent dyspepsic diarrhea in this stage. 相似文献
14.
15.
Milagros Virhuez MENDOZA Kenzo YONEMITSU Keita ISHIJIMA Yudai KURODA Kango TATEMOTO Yusuke INOUE Hiroshi SHIMODA Ryusei KUWATA Ai TAKANO Kazuo SUZUKI Ken MAEDA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2022,84(7):992
In Japan, hepatitis E virus (HEV) causes hepatitis in humans through the consumption of raw or undercooked meat, including game meat. In the present study, nationwide surveillance of HEV infection among a total of 5,557 wild animals, including 15 species, was conducted in Japan. The prevalence of anti-HEV antibodies in wild boar was 12.4%, with higher positive rates in big boars (over 50 kg, 18.4%) than in small individuals (less than 30 kg, 5.3%). Furthermore, HEV RNA was more frequently detected in piglets than in older boars. Interestingly, the detection of HEV among wildlife by ELISA and RT-PCR suggested that HEV infection in Sika deer was a very rare event, and that there was no HEV infection among wild animals except for wild boar, Sika deer and Japanese monkeys. In conclusion, wild boar, especially piglets, are at high risk of HEV infection, while other wild animals showed less risk or no risk of HEV transmission. 相似文献
16.
Kazuki TAKAHASHI Yasuyuki KANEKO Akiko SHIBANAI Shushi YAMAMOTO Ayana KATAGIRI Tatsuyuki OSUGA Yoshiyuki INOUE Kohei KURODA Mika TANABE Tamaki OKABAYASHI Kiyokazu NAGANOBU Isao MINOBE Akatsuki SAITO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2022,84(5):648
The hepatitis B virus (Hepadnaviridae) induces chronic hepatitis and hepatic cancer in humans. A novel domestic cat hepadnavirus (DCH) was recently identified in several countries, however, the DCH infection status of cats in Japan is unknown. Therefore, we investigated the DCH infection rate of 139 cat samples collected in Japan. We identified one positive blood sample (0.78%) from a 17-year-old female cat with chronically elevated alanine aminotransferase. Phylogenetic analysis demonstrated that the DCH strain identified in this study is genetically different from strains in other countries. Further investigations are required to elucidate the evolution of DCH and the impact of DCH infection on hepatic diseases in domestic cats. 相似文献
17.
Vonika NOU Kyouko TOMOSHI Hiroaki INOUE Hideto KUWAYAMA Hisashi HIDARI 《Animal Science Journal》2003,74(2):129-136
To investigate the effects of high and low somatostatinergic tone on GH-releasing peptide-2 (GHRP-2) and GH-releasing hormone (GHRH)-induced growth hormone (GH) secretion in swine, we examined GHRP-2- and GHRH-induced GH secretion after pretreatment with atropine or pyridostigmine. Pretreatment of swine with atropine (80 µg/kg bodyweight (BW), intravenous (i.v.)) 15 min before i.v. administration of saline, GHRP-2 (30 µg/kg BW), GHRH (1 µg/kg BW) or a combination of GHRP-2 and GHRH, reduced plasma GH area under the curve ( P < 0.05), completely blocked GH response to GHRH, and attenuated GH response to GHRP-2 and GHRH combined ( P < 0.05), without affecting GH response to GHRP-2 only. A synergistic effect of GHRP-2 and GHRH was not observed. In contrast, pretreatment of swine with pyridostigmine (100 µg/kg BW, i.v.), under the same pretreatment conditions as above, increased plasma GH concentration ( P < 0.01), augmented GH response to GHRP-2 ( P < 0.05), and GHRP-2 and GHRH combined ( P < 0.05), but did not affect GH response to GHRH. These results suggest that the cholinergic muscarinic agents atropine and pyridostigmine modulate the GH response to GHRP-2 and GHRH, and that GHRP-2 acts antagonistically on the inhibitory effect of somatostatin in swine. 相似文献
18.
Yoshinobu INOUE Akira MATSUI Yo ASAI Fumiki AOKI Kenji YOSHIMOTO Tohru MATSUI Hideo YANO 《Journal of Equine Science》2008,19(4):83-89
We studied the response of biochemical markers of bone metabolism to exercise intensity
in horses. Four horses were walked on a mechanical walker for one week (pre-exercise).
Then they performed low-speed exercise on a high-speed treadmill in the first week and
medium-speed exercise in the second week and high-speed exercise in the third week of
training. We measured two indices of bone resorption, serum hydroxyproline concentration
and the urinary deoxypyridinoline/creatinine ratio, and serum osteocalcin (OC)
concentration as an index of bone formation. Both indices of bone resorption gradually
decreased during the experiment. Serum OC concentration did not change in the first week
but was significantly lower in the second and the third weeks compared to in the
pre-exercise period and in the first week. These results suggest that the low-speed
exercise decreased bone resorption but did not affect bone formation, which possibly
results in increasing bone mineral content and strengthening of bones. The high-speed
exercise decreased bone formation and bone resorption, i.e., bone turnover was suppressed.
The low-speed exercise may be preferable for increasing bone mineral content. 相似文献
19.
Mai INOUE Katsuaki SUGIURA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2021,83(7):1039
This study aimed to identify the causes of death in dogs that were buried at pet cemeteries. Using data obtained from a questionnaire completed by 5,118 dog owners from 1 April 2016 to 31 March 2017, we estimated the life expectancy and the odds ratio for principal causes of death using multiple logistic regression analysis with potential risk factors as independent variables. The life expectancy determined at birth was 13.98 years. The commonest cause of death was senility. The odds ratios of dying of senility being significantly higher in Labrador Retrievers and Shiba breeds and aged dogs, and significantly lower in Chihuahuas, dogs living indoors and neutered dogs. 相似文献
20.
Digestive enzyme activities of pancreas and intestinal digesta in streptozotocin-induced diabetic piglets 总被引:1,自引:0,他引:1
Hitoshi MURAKAMI Mitsuhito MATSUMOTO Hiroaki INOUE Yuji KAJI 《Animal Science Journal》2007,78(1):55-60
Six (Landrace × Large White) × Duroc crossbred, castrated weanling piglets were used to evaluate the effect of a streptozotocin (STZ) injection to induce diabetes on the activities of digestive enzymes derived from the pancreas (lipase, amylase, trypsin and chymotrypsin) in the pancreas and intestinal digesta. Fasting plasma glucose after the administration of STZ was maintained at the level of 302–491 mg/dL during this experiment, compared with the level of 89–125 mg/dL in the control group, and they were defined as the STZ‐induced diabetic piglets for about 7 weeks. Although their bodyweight increased in proportion to a quadratic curve (P < 0.0001) during 49 days after the administration of STZ, the growth of the STZ‐induced diabetic piglets was slower compared with the control. The STZ‐injection did not affect the percentage of the pancreas in bodyweight. The administration of STZ in the piglets tended to accelerate the activity of lipase (P = 0.06) and depress the activity of amylase (P = 0.15) or chymotrypsin (P = 0.18), as units/kg bodyweight, in the pancreas. In the case of measurement as units/kg bodyweight, the activities of intestinal digesta in the STZ group showed a tendency to be higher than those in control group, irrespective of the sort of enzymes. In conclusion, STZ‐induced diabetic piglets have a moderate digestive ability and the administration of exogenous digestive enzymes is not necessary when they are used as a diabetic animal model. 相似文献