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排序方式: 共有325条查询结果,搜索用时 125 毫秒
321.
Tomokazu Ohta Katsuo Koshi Koichi Ushizawa Misa Hosoe Toru Takahashi Takahiro Yamaguchi Keiichiro Kizaki Kazuyoshi Hashizume 《Animal Science Journal》2014,85(7):763-769
The conceptus is susceptible to destruction by maternal cytotoxic lymphocytes, which have cytotoxic potential. Therefore, it is expected that mechanisms for regulating cytotoxic lymphocytes exist, but little is known about the expression of cytotoxic genes in the endometrium. In the present study, we examined the spatial and temporal expression patterns of the cytotoxic genes perforin, granzyme B, and granulysin during the estrous cycle and gestation in the bovine endometrium. Endometrial tissues were collected from cows during the estrous cycle and gestation. The gene expression patterns of the three cytotoxic genes were examined using quantitative polymerase chain reaction and in situ hybridization, and cytotoxic lymphocyte subsets were characterized using immunohistochemistry. During mid‐ to late gestation in the intercaruncular (ICAR), granulysin expression was significantly increased, and a large number of granulysin‐expressing cells were localized in the luminal epithelium. Perforin and granzyme B displayed similar expression profiles and were highly expressed in the peri‐implantation endometrium, but few cells expressing these genes were found in the endometrial stroma. In conclusion, these findings suggest that in the ICAR epithelium granulysin may play important roles in the establishment and maintenance of gestation during normal pregnancy. 相似文献
322.
Three hardwoods of varying vessel arrangement were treated with the ionic liquid, 1-ethyl-3-methylimidazolium chloride ([C2mim][Cl]), which can dissolve cellulose, to investigate its influence on wood tissue morphology. Characterization was carried out by light and scanning electron microscopy. The wood fibers of all species swelled significantly during [C2mim][Cl] treatment. The swelling behavior varied according to wood species and differed from other cell types such as ray parenchyma cells. Morphological changes of the pits also varied between wood species. Treatment with [C2mim][Cl] affects wood tissues differently depending on wood species and cell type. These differences are not due to the vessel arrangement and its presence, but possibly from the chemical component and the microfibril angle of various wood tissues. 相似文献
323.
Mariko Nagatani Kayoko Kudo Seiki Yamakawa Toko Ohira Yuko Yamaguchi Shinichiro Ikezaki Isamu Suzuki Tsubasa Saito Toru Hoshiya Kazutoshi Tamura Kazuyuki Uchida 《Journal of toxicologic pathology》2013,26(3):263-273
In order to accurately assess the carcinogenicity of chemicals with regard to rare
tumors such as rat CNS tumors, sufficient information about spontaneous tumors are very
important. This paper presents the data on the type, incidence and detected age of CNS
tumors in F344/DuCrlCrlj (a total of 1363 males and 1363 females) and Crl:CD(SD) rats (a
total of 1650 males and 1705 females) collected from in-house background data-collection
studies and control groups of carcinogenicity studies at our laboratory, together with
those previously reported in F344 and SD rats. The present data on F344/DuCrlCrlj rats
(F344 rats) and Crl:CD(SD) rats (SD rats) clarified the following. (1) The incidences of
all CNS tumors observed in F344 rats were less than 1%. (2) The incidences of malignant
astrocytoma and granular cell tumor were higher in male SD rats than in female SD rats.
(3) The incidences of astrocytoma and granular cell tumor were higher in SD rats than in
F344 rats. (4) Among astrocytoma, oligodendroglioma and granular cell tumor,
oligodendroglioma was detected at the youngest age, followed by astrocytoma, and
ultimately, granular cell tumor developed in both strains. The incidences observed in our
study were almost consistent with those previously reported in F344 and SD rats. 相似文献
324.
Trimethylamine-N-oxide (TMAO) degrades to dimethylamine (DMA) and formaldehyde, which cause a decline in fish quality. Suppression of DMA
formation in frozen surimi was investigated using croaker, lizardfish, and walleye pollock. The leaching process in surimi
processing was shown to reduce not only the TMAO, iron, and taurine content, but also to reduce unidentified factors that
accelerate DMA formation in lizardfish muscle; in contrast, unidentified factors that suppress DMA formation were reduced
in croaker and pollock muscle. Sucrose, used as a cryoprotectant, was shown to decrease DMA formation in vitro, likely due
to the reduction in freezing-induced concentration of solutes. The effects of pH on DMA formation were different in minced
frozen meat among the three species. DMA formation was not observed in croaker when the pH varied between 6 and 8. On the
other hand, DMA was elevated in lizardfish under acidic conditions, and DMA formation in pollock was maximal when the pH of
the meat was neutral. Thus, the suppression of TMAO degradation by surimi processing results from the removal of TMAO, iron,
and reductants from fish meat; sucrose also reduces DMA formation. Furthermore, unidentified factors in croaker, lizardfish,
and pollock meat substantially affect DMA formation. 相似文献
325.
Norio Shirafuji Toru Nakagawa Naoto Murakami Sayaka Ito Toshihiro Onitsuka Taizo Morioka Yoshiro Watanabe 《Fisheries Science》2018,84(2):227-236
Distributions of eggs, larvae and juveniles of Pacific herring Clupea pallasii were surveyed in Lake Akkeshi and the connecting Akkeshi Bay on the Pacific coast of eastern Hokkaido. Eggs were found attached to seagrasses and seaweeds in the densely vegetated eastern inner lake. Larvae (7.1–34.9 mm total length) were distributed in the less densely vegetated inner lake during April and June. Juveniles (35.0–89.6 mm) were collected in the central and western parts of the lake. The sites containing juveniles were less densely vegetated with water temperatures lower than 20 °C from June to August. When the water temperature of the entire lake rose to 20 °C in late summer, juveniles appeared to move from the lake to the bottom layer of Akkeshi Bay, which has lower temperatures. Thus, in Akkeshi waters, C. pallasii successively used different habitats during its egg, larval and juvenile stages. A comparison of the current limited distribution of eggs and larvae with the distribution over the entire lake and bay areas in the 1950s and 1960s (periods of large catch size) indicates that the spawning grounds and larval habitats of C. pallasii have contracted to the lake area due to low spawning stock biomass in recent years. 相似文献