成品油管道水击超前保护优化方案

成品油管道发生泵站意外停电事故后通常执行水击超前保护程序,该保护方案对管道的安全性有决定性影响。为了确保管道从事故前稳态安全平稳过渡到事故后较优的运行状态,需要制定最佳的水击超前保护方案。对成品油管道泵站意外停电水击工况进行分析,以水击事故发生后下一稳态时输量最大且各调节阀节流压力之和最小为目标,建立优化模型,相应的约束条件为全线不超压、不汽化。模型求解采取两种不同策略:事故站下游以各站出站压力最低为目标分别寻优,采用水力坡降线平移法求解;事故站上游以整体总节流最小寻优,为了提高求解速度,采用深度优先搜索法求解。以某成品油管道泵站意外停电事故工况为例,对该优化模型进行实例应用,并根据优化结果制定水击事故过渡过程的控制逻辑,并使用仿真软件SPS验证了控制逻辑的合理性,表明该优化模型合理可靠。     

浅谈农业科研单位职工思想政治工作与现代管理的有效结合

面对新形势、新任务,思想政治工作在继承和发扬优良传统的基础上,必须在内容、形式、方法、手段等方面进行创新和改进。本文结合农业科研基层单位的特点,探讨了职工思想政治工作与现代管理的有效结合点。     

慈竹生长过程纤维素、木质素及灰分动态积累

以当年生不同生长高度的慈竹为研究对象,探讨慈竹生长过程中纤维素、木质素和灰分含量的积累规律。结果表明:慈竹不同生长高度纤维素含量顶、中部变化趋势均以对数方式增长;基部纤维素含量和茎秆纤维素总含量变化趋势都呈"S型"曲线;各部位木质素含量变化趋势总体呈倒"S型"曲线,且不同高度间的木质素含量的差异达显著水平;随着生长高度的增高,茎秆顶部、基部灰分含量以及茎秆灰分总含量总体呈倒"S型"曲线变化,中部灰分含量总体呈"S型"曲线变化。纤维素总含量、木质素总含量的积累分别集中在茎秆高度为150~800、30~800 cm这个生长时期;灰分总量在300~800 cm保持较高的水平。     

基于读者信息行为规律的信息服务管理策略

论述了网络环境下,高校图书馆读者信息行为规律的变化及共性特征,并进行了实证分析研究。在此基础上,提出了图书馆多样化、多元化、个性化和一站式的信息服务管理策略。     

水利建设可持续发展刍议

首先分析了水利建设与可持续发展的关系,即可持续发展对水利建设提出了新要求、丰富了新思路,水利建设实践推动了水利可持续发展研究,并基于此提出水利建设可持续发展思路,即树立可持续发展意识,推进水利建设制度创新;人水协调,加强水利现代化建设.     

气肿疽梭菌细胞毒素CctA基因的克隆及生物信息学分析

根据GenBank中气肿疽梭菌细胞毒素CctA基因的参考序列,采用PCR方法扩增细胞毒素CctA基因。在将该基因进行克隆和测序后利用生物信息学方法,对细胞毒素CctA蛋白的理化性质、结构功能域、蛋白质二级结构和三级结构及抗原表位等重要参数进行了预测和分析。结果表明:与参考序列(JQ692583)相比,存在3处突变,核苷酸序列的同源性和氨基酸序列的同源性均为99.4%;CctA蛋白的理论等电点为8.00,不存在跨膜区和信号肽序列,二级结构以β-折叠和无规则卷曲为主,主要有4个抗原表位区域。本研究为CctA蛋白功能的深入研究提供了参考,并为气肿疽梭菌单克隆抗体的制备及合成肽疫苗的研发奠定了基础。     

柞蚕新品种永青的选育

柞蚕新品种永青是以“青六号”为基础材料,利用系统选育手段,采用分区饲养、系统分离、定向培育的方法,同时兼顾各项经济指标的综合平衡,通过9年18代的系统选育,育成的具有青黄蚕血统的柞蚕新品种。选育结果：全茧量12.47g,千粒茧重11.99kg,虫蛹统一生命率94.81%;与吉柞88-2、方山黄杂交,增产幅度达15.5%以上。     

试验统计方法课程教学改革探索与实践

介绍了试验统计方法课程的基本理论体系和教学目标,指出了试验统计方法课程教学中存在的主要问题,并提出了课程教学改革理念及思路,以为试验统计方法课程教学改革提供参考。     

Cell direct reprogramming：a new technique for treating diabetes

Diabetes is characterized by an absolute or relative deficiency in β-cell mass, which cannot be reversed with existing therapeutic strategies. The restoration of the endogenous islet β-cells can stabilize the level of blood glucose. The islet β-cells can be obtained from the directional differentiation of stem cells, but the process is complex and has the risk of teratomas generation. Cell direct reprogramming, one terminal differentiated cell can transdifferentiate into another kind of terminal differentiated cell, which is other than directional differentiation from stem cells. Direct reprogramming gives rise to the generation of islet β-cells from one terminal differentiated cell, may be preferable for diabetes therapy because of its unique advantage.     

Bioinformatics Analysis of Bone Morphogenetic Protein 4 (BMP4) of Sheep

The assay was aimed to explore the biological characteristics of bone morphogenetic protein 4 (BMP4) of sheep,NCBI,DNAMAN DNAStar,TMHMM Server v.2.0,PsortⅡ,SignalP various bioinformatical softwares were used to speculate the physical and chemical properties,hydrophobic property,phosphorylation site,conservative structure domain,protein secondary structure of BMP4 protein.Also,the three-dimensional structure was forecasted with the SWISS-MODEL Workspace software.The results indicated that the BMP4 of sheep had high homologies with the BMP4 of various species.The encoded protein was a hydrophilic protein which was unstable.There was no transmembrane regions and it was likely to be located in the nucleus.What was more,there was signal peptide and eighteen phosphorylation sites.Through the forecast of functional domains,the protein had two functional domains,including the transforming growth factor-beta (TGF-beta) superfamily and TGF-beta propeptide superfamily.The result was consistent with the function of BMP4 gene family,it also demonstrated that BMP4 was a growth factor and it had the function of signal transduction.The amino acid homology between the predicted 3D structure of protein and template 3bmp.1.A was 88.29%.The bioinformatics analysis of BMP4 gene could provide reference for the further study in practice.