Cervical intervertebral disc protrusion in two horses

Two horses with ataxia of all four limbs were found to have cervical intervertebral disc protrusion. Severe pelvic limb ataxia, proprioceptive deficits and spasticity were present in both horses with similar but less severe signs in the thoracic limbs. Cerebrospinal fluid analysis was within normal limits. Metrizamide myelography allowed definitive diagnosis in one case when a compression of the spinal cord was demonstrated at the level of the second intervertebral space. In the second case, an intervertebral disc protrusion between cervical vertebrae 6 and 7 was found at necropsy. Fiber degeneration with poor myelin staining characterized the spinal cords histologically.     

A strategy for control of bovine leukemia virus infection: test and corrective management

Test and corrective management was applied in one dairy herd (130 milking cows) to control bovine leukemia virus infection. It consisted of: raising uninfected calves in order to establish a pool of uninfected replacement heifers, preventing transmission of bovine leukemia virus through transfer of blood from animal to animal and closing the herd. Regular herd testing was combined with selected changes in herd management. These procedures have been followed since January 1979. Prevalence of antibodies (as determined by gel-immunodiffusion) has declined markedly since the program was implemented.     

The duration of immunity to an inactivated adjuvanted canine parvovirus vaccine. A 52 and 64 week postvaccination challenge study

Dogs were successfully isolated for a period of either 52 or 64 weeks following vaccination with an inactivated, adjuvanted canine parvovirus-2 vaccine. Antibody persisted in all ten vaccinated dogs, although in one case by 52 weeks postvaccination only virus neutralizing antibody, and not hemagglutination-inhibiting antibody, could be detected. Sentinel unvaccinated dogs housed alongside the vaccinated dogs throughout the study remained free of canine parvovirus-2 antibody until challenged. Upon oral challenge with canine parvovirus-2 infected material all unvaccinated dogs developed one or more signs of canine parvovirus-2 disease, shed virus and developed antibody. None of the vaccinated dogs became overtly sick. Of the five vaccinated dogs challenged 52 weeks after vaccination, three shed virus and one showed a significant rise in antibody. At 64 weeks after vaccination only one of the five challenged dogs shed virus and showed a boost in antibody titer.     

Treatment of sarcoptic mange in canadian cattle with ivermectin

In 1982, approximately 13,000 Canadian cattle were treated once for sarcoptic mange with ivermectin at a dose of 10 mg per 45.4 kg of body weight. The results showed 100% efficacy against Sarcoptes scabiei and other ectoparasites present. All cattle showed marked improvement in general condition with new hair growth and apparent weight gains by 31 days posttreatment. Surveillance of treated herds for a year following treatment showed that one parenteral treatment with ivermectin eradicated the disease from closed herds.