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Disseminated aspergillosis in dogs 总被引:1,自引:0,他引:1
M J DAY W J PENHALE M J KABAY W F ROBINSON C R R HUXTABLE C E EGER† S E SHAW† J N MILLS† R S WYBURN† 《Australian veterinary journal》1986,63(2):55-59
Clinical and pathological findings are reported from a series of 12 cases of disseminated aspergillosis (A. terreus) in 11 German Shepherd dogs and one Dalmatian referred to Murdoch University Veterinary Hospital (MUVH) over the period 1980 to 1984. A preliminary study of humoral and cell mediated immune components and complement levels revealed no consistent abnormality in 9 dogs tested apart from raised IgG levels. Serum IgA levels were depressed in 30% of cases. Serial data from one extensively monitored case is presented. The unusual epidemiological and pathogenetic features of the disease are discussed. 相似文献
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The relative pathogenicity of isolates of Macrophomina phaseolina was comparable both on sunflower tissue cultures and on mature plants and seedlings. The relative susceptibility of the different sunflower lines in vitro showed a similar pattern for cotyledon callus cultures, but not for immature embryo cultures. Although these protocols appear to be unsuitable for the selection of novel disease resistance, they do offer the potential for a rapid, non-destructive screen for resistant material. 相似文献
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THOMAS K. DAY DVM MS Diplomate AVCA JAMES S. GAYNOR DVM MS Diplomate ACVA WILLIAM W. MUIR III DVM PhD Diplomate ACVA RICHARD M. BEDNARSKI DVM MS Diplomate ACVA DIANE E. MASON DVM MS Diplomate ACVA 《Veterinary surgery : VS》1995,24(3):266-276
One hundred sixty horses were anesthetized with xylazine, guaifenesin, thiamylal, and halothane for elective soft tissue and orthopedic procedures. Horses were randomly assigned to one of four groups. Group 1 (n = 40): Horses positioned in lateral (LRG1,; n = 20) or dorsal (DRG1,; n = 20) recumbency breathed spontaneously throughout anesthesia. Group 2 (n = 40): Intermittent positive pressure ventilation (IPPV) was instituted throughout anesthesia in horses positioned in lateral (LRG2; n = 20) or dorsal (DRG2; n = 20) recumbency. Group 3 (n = 40): Horses positioned in lateral (LRG3; n = 20) or dorsal (DRG3; n = 20) recumbency breathed spontaneously for the first half of anesthesia and intermittent positive pressure ventilation was instituted for the second half of anesthesia. Group 4 (n = 40): Intermittent positive pressure ventilation was instituted for the first half of anesthesia in horses positioned in lateral (LRG4; n = 20) or dorsal (DRG4; n = 20) recumbency. Spontaneous ventilation (SV) occured for the second half of anesthesia. The mean time of anesthesia was not significantly different within or between groups. The mean time of SV and IPPV was not significantly different in groups 3 and 4. Variables analyzed included pH, PaCO2, PaO2, and P(A-a)O2 (calculated). Spontaneous ventilation resulted in significantly higher PaCO2 and P(A-a)O2 values and significantly lower PaO2 values in LRG1, and DRG1, horses compared with LRG2 and DRG2 horses. Intermittent positive pressure ventilation resulted in normocarbia and significantly lower P(A-a)O2 values in LRG2 and DRG2 horses. In LRG2 the Pao2 values significantly increased from 20 minutes after induction to the end of anesthesia. The PaO2 and P(A-a)O2 values were not significantly different from the beginning of anesthesia after IPPV in DRG2 or DRG3. The PaO2 values significantly decreased and the P(A-a)O2 values significantly increased after return to SV in horses in LRG4, and DRG4. The PaO2 values were lowest and the P(A-a)O2 values were highest in all horses positioned in dorsal recumbency compared with lateral recumbency and in SV horses compared with IPPV horses. The pH changes paralleled the changes in PaCO2. Blood gas values during right versus left lateral recumbency in all groups were also evaluated. The PaO2 values were significantly lower and the P(A-a)O2 values were significantly higher during SV in horses positioned in left lateral (LRLG1) compared with right lateral (LRRG1) recumbency. No other significant changes were found comparing left and right lateral recumbency. Arterial hypoxemia (PaO2 < 60 mm Hg) developed in 35% of DRG1 horses and 20% of DRG2 horses at the end of anesthesia. Arterial hypercarbia (PaCO2= 50–60 mm Hg) developed in DRoi horses. Arterial hypoxemia that developed in 20% of DRG3 horses was not improved with IPPV. Arterial hypoxemia developed in 55% of DRG4 horses after return to SV. Some DRG4 horses with hypoxemia also developed hypercarbia, whereas some had PaCO2 values within normal limits. Arterial hypoxemia developed in one LRG1, and two LRG4, horses. Hypercarbia developed in onlv one LRG4 horse. 相似文献
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Comparison of Intra-articular and Epidural Morphine for Analgesia Following Stifle Arthrotomy in Dogs 总被引:1,自引:0,他引:1
THOMAS K. DAY DVM MS Diplomate ACVA WILLIAM T. PEPPER DVM TODD A. TOBIAS DVM MS Diplomate ACVS MICHAEL F. FLYNN DVM Diplomate ACVS KEVIN M. CLARKE DVM 《Veterinary surgery : VS》1995,24(6):522-530
We prospectively studied 18 dogs that presented for exploratory stifle arthrotomy, with or without meniscectomy, and lateral extracapsular stabilization as a result of cranial cruciate ligament rupture. Dogs were premedicated with acepromazine, induced with thiopental, and maintained with halothane in oxygen. Preoperatively, dogs were assigned to one of three groups. Group 1 (n = 6) received intra-articular morphine (0.1 mg/kg diluted in 1 mL/10 kg body weight of saline) and epidural saline (1 mL/5 kg body weight saline plus the volume of saline representing 0.1 mg/kg of morphine). Group 2 (n = 6) received intra-articular saline (1 mL/10 kg body weight of saline plus the volume of saline representing 0.1 mg/kg of morphine) and epidural saline (1 mL/5 kg body weight saline plus the volume of saline representing 0.1 mg/kg of morphine). Group 3 (n = 6) received intra-articular saline (1 mL/10 kg body weight of saline plus the volume of saline representing 0.1 mg/kg of morphine) and epidural morphine (0.1 mg/kg of morphine diluted in 1 mL/5 kg body weight saline). The efficacy of each analgesia regimen was evaluated for 6 hours postoperatively with a pain score based on subjective and objective variables. Serum Cortisol and blood glucose concentrations were measured. Butorphanol was used to provide analgesia as needed based on a predetermined maximum pain score. Supplemental analgesics were required postoperatively every 2 to 3 hours for 6 hours in all dogs that did not initially receive analgesics (group 2). Pain scores were significantly lower in dogs administered morphine intra-articularly (group 1) and epidurally (group 3) at 30 minutes and 30, 120, and 360 minutes, respectively, compared with dogs that did not initially receive analgesics (group 2). One dog in group 1 and one dog in group 3 required supplemental analgesia with butorphanol. There was no difference between analgesia produced by intra-articular morphine compared with that of epidural morphine. Side effects after intra-articular or epidural morphine were not observed. Intra-articular administration of morphine can produce effective analgesia in dogs comparable with that produced by epidural administration of morphine. 相似文献
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