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41.
Role of adenine nucleotide translocator 1 in mtDNA maintenance 总被引:1,自引:0,他引:1
Kaukonen J Juselius JK Tiranti V Kyttälä A Zeviani M Comi GP Keränen S Peltonen L Suomalainen A 《Science (New York, N.Y.)》2000,289(5480):782-785
Autosomal dominant progressive external ophthalmoplegia is a rare human disease that shows a Mendelian inheritance pattern, but is characterized by large-scale mitochondrial DNA (mtDNA) deletions. We have identified two heterozygous missense mutations in the nuclear gene encoding the heart/skeletal muscle isoform of the adenine nucleotide translocator (ANT1) in five families and one sporadic patient. The familial mutation substitutes a proline for a highly conserved alanine at position 114 in the ANT1 protein. The analogous mutation in yeast caused a respiratory defect. These results indicate that ANT has a role in mtDNA maintenance and that a mitochondrial disease can be caused by a dominant mechanism. 相似文献
42.
Johansson L Rytkonen A Bergman P Albiger B Källström H Hökfelt T Agerberth B Cattaneo R Jonsson AB 《Science (New York, N.Y.)》2003,301(5631):373-375
The human-specific bacterial pathogen Neisseria meningitidis is a major cause of sepsis and/or meningitis. The pili of N. meningitidis interact with CD46, a human cell-surface protein involved in regulation of complement activation. Transgenic mice expressing human CD46 were susceptible to meningococcal disease, because bacteria crossed the blood-brain barrier in these mice. Development of disease was more efficient with piliated bacteria after intranasal, but not intraperitoneal, challenge of CD46 transgenic mice, suggesting that human CD46 facilitates pilus-dependent interactions at the epithelial mucosa. Hence, the human CD46 transgenic mice model is a potentially useful tool for studying pathogenesis and for vaccine development against meningococcal disease. 相似文献
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Heljä-Sisko Helmisaari Lilli Kaarakka Bengt A. Olsson 《Scandinavian Journal of Forest Research》2014,29(4):312-322
The review gives an overview of the increased utilization of forest biomass for energy. The emphasis is on Nordic countries, especially on Sweden and Finland with large biomass potentials and a high share of renewable energy in gross final energy consumption. The utilization and potential of forest chip sources such as logging residues, small-size tree stems and stumps that are normally not harvested in conventional harvesting are described. Environmental potential and impacts that may reduce the utilization of forest biomass are discussed based on recent publications. Finally, the review summarizes the future developments based on their relationship to policies, certifications and guidelines and forest owners' decisions. 相似文献
45.
Samuli Junttila Mikko Vastaranta Jarno Hämäläinen Petri Latva-käyrä Markus Holopainen Rocío Hernández Clemente 《Scandinavian Journal of Forest Research》2017,32(2):154-165
The effect of forest structure and health on the relative surface temperature captured by airborne thermal imagery was investigated in Norway Spruce-dominated stands in Southern Finland. Airborne thermal imagery, airborne scanning light detection and ranging (LiDAR) data and 92 field-measured sample plots were acquired at the area of interest. The surface temperature correlated most negatively with the logarithm of stem volume, Lorey’s height and the logarithm of basal area at a resolution of 254?m2 (9?m radius). LiDAR-derived metrics: the standard deviations of the canopy heights, canopy height (upper percentiles and maximum height) and canopy cover percentage were most strongly negatively correlated with the surface temperature. Although forest structure has an effect on the detected surface temperature, higher temperatures were detected in severely defoliated canopies and the difference was statistically significant. We also found that the surface temperature differences between the segmented canopy and the entire plot were greater in the defoliated plots, indicating that thermal images may also provide some additional information for classifying forests health status. Based on our results, the effects of forest structure on the surface temperature captured by airborne thermal imagery should be taken into account when developing forest health mapping applications using thermal imagery. 相似文献
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M. v. Cotta M. v. Cotta Mördes v. Pannewib Robert Rühn Paur v. Stelzl v. Deltheim Schulze Q. v. Mikleben Lreiherr v. Lflanteuffel Lreiherr v. Berg Qeitel M. Lreiherr v. Berg v. Michael H. C. Bär Baer A. Chieriod Berger Rettftadt Gekner Wlrici Lreiherr v. Schmerzing Sprenger Pommrich v. Strune Matufchka v. E. Q. Brunft Rnaudt Mördlinger Rnipping v. Mangenheim C. A. Baum L. Mehlborn G. v. Stieglik H. v. Biegefar C. Grebe v.n Baumbach Braun R. Blohmer 《European Journal of Forest Research》1865,9(1):322-324
Ohne Zusammenfassung
f. f?chf. Dberforftmeifter.
f. bahr. Regierungs- und Forftrath von Mürzburg.
f. preuk. Dberforftmeifter aus Breslau.
f. f?chf. Dberforftmeifter.
f. bahr. Regierungs- und Forftrath von Augsburg.
f. bahr. Regierungs- und Forftrath aus Regensburg.
Dberj?germeifter von Braunfchweig.
f. bahr. Regierungs- und Forftrath aus München.
f. f?chf. Dberf?rfter.
f. f?chf. Dberforftmeifter.
f. f?chf. Dberforftrath.
herz. braunfchweig. Forftmeifter von Blanfenburg.
Direftor der fürftlich Cfterhazh’fchen Herrfchaft Spoly Parsto.
fürftl. fondershauf. Dberfortmeifter.
f. bahr. Redierf?rfter don Schmarzenbach.
f. preuk. Dberf?rfter.
f. f. Forftrath aus Brekburg.
f. preuk. Dberf?rfter von Altruppin.
f. hann?v. Forftmeifter von Rienburg.
Forftmeifter in preuk. Schleften.
f. preuk. Dberforftmeifter von Berlin.
herz. aftenburg. Dberfortmeifter.
f. preuk. Dberf?rfter.
f. f?chf. Dberf?rfter.
f. ruff. Forftfomiff?r aus Marfchau.
f. preuk. Forftinfpeftor.
f. f?chf. Forftinfpeftor.
grokh. meimar. Forftinfpeftor von Martfuhl.
f. mürttb. Dberf?rfter und Brofeffor aus Hohenheim.
f. hannov. Forftmeifter aus Hammeln.
Dberforftmeifter aus Sotha.
herz. altenburg. Dberf?rfter aus Hummelshain.
herz. altenburg. Revierf?rfter aus Milchwig.
herz. altenburg. geheimer Finanzrath und Dberforftmeifter.
herz. altenb. Dberforftmeifter aus Hummelshain.
grokh. f?chf. geheimer Dberforftrath aus Qifenach.
herz. naffau. Dberforftrath aus Miesbaden.
grokh. heff. Dberforftfefret?r aus Darmftadt.
f. f?chf. Dberforftmeifter. 相似文献
48.
R. Sächf. Dberforftrath 《European Journal of Forest Research》1862,6(1):161-185
Ohne Zusammenfassung 相似文献
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Redierfőrfter Läger 《European Journal of Forest Research》1857,1(8):336-338
Ohne Zusammenfassung 相似文献