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181.
Coastal Social–Ecological Systems (SESs) are subject to several stresses, including climate change, that challenge fisheries and natural resource management. Fishers are front‐line observers of changes occurring both on the coast and in the sea and are among the first people to be affected by these changes. In this study, we perform a meta‐analysis of observations and adaptations to climate change by subsistence‐oriented coastal fishers extracted from a global review of peer‐reviewed and grey literature. Fishers' observations compiled from across the globe indicate increased temperatures and changes in weather patterns, as well as coastal erosion, sea level rise and shifts in species range and behaviours. Coastal areas offer a wide array of resources for diversifying livelihoods, but climate change is reducing these options. Specifically, climate change could reduce the resilience of fishers' communities, limiting options for diversification or forcing fishers to abandon their houses or villages.  相似文献   
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Plant Foods for Human Nutrition - Functional food with high concentrations of monosaccharides and antioxidants is important for quick replenishment of energy reserves and rehabilitation after...  相似文献   
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Quince (Cydonia oblonga Miller) fruit aqueous acetone extracts were evaluated. High-performance liquid chromatography-diode array detection and electrospray ionization-mass spectrometry were used for the identification and quantification of the phenolic compounds. The total phenolic content of the pulp and peel parts ranged from 37 to 47 and 105 to 157 mg/100 g of fresh weight, respectively. Chlorogenic acid (5-O-caffeoylquinic acid) was the most abundant phenolic compound in the pulp (37%), whereas rutin (quercetin 3-O-rutinoside) was the main one in the peel (36%). The radical scavenging potential of the extracts was determined and compared with that of synthetic antioxidants. The stronger properties corresponded to those obtained from peel material with a 70-80% inhibitory effect on DPPH radicals. The antimicrobial activity of the extracts against different microorganism strains was also investigated. Quince peel extract was the most active for inhibiting bacteria growth with minimum inhibitory and bactericide concentrations in the range of 102-5 x 103 microg polyphenol/mL. It seems that chlorogenic acid acts in synergism with other components of the extracts to exhibit their total antimicrobial activities.  相似文献   
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Cancer affects more than 19 million people and is the second leading cause of death in the world. One of the principal strategies used in cancer therapy is the inhibition of topoisomerase II, involved in the survival of cells. Side effects and adverse reactions limit the use of topoisomerase II inhibitors; hence, research is focused on discovering novel compounds that can inhibit topoisomerase II and have a safer toxicological profile. Marine organisms are a source of secondary metabolites with different pharmacological properties including anticancer activity. The objective of this review is to present and discuss the pharmacological potential of marine-derived compounds whose antitumor activity is mediated by topoisomerase II inhibition. Several compounds derived from sponges, fungi, bacteria, ascidians, and other marine sources have been demonstrated to inhibit topoisomerase II. However, some studies only report docking interactions, whereas others do not fully explain the mechanisms of topoisomerase II inhibition. Further in vitro and in vivo studies are needed, as well as a careful toxicological profile evaluation with a focus on cancer cell selectivity.  相似文献   
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The growth of evergreen azaleas (Rhododendron spp.) can be altered by iron (Fe) chlorosis when plants are cultivated in a neutral-alkaline substrate. In this study, morphological and physiological responses to alkalinity and Fe deficiency were evaluated in five diploid Japanese azaleas to assess their potential as resources for breeding. R. obtusum ‘Kirin’, R. indicum ‘Shinsen’, R. × pulchrum ‘Sen-e-oomurasaki’, R. indicum ‘Osakazuki’, and R. ripense were pot cultivated in a peat-based substrate for 10 weeks, in acid and alkaline growing media with both adequate and inadequate Fe nutrition. Plant performance was generally affected by high pH of the substrate, while Fe deficiency by itself influenced few of the evaluated parameters, possibly due to the complex adaptive response mechanisms of these slow growing ornamental shrubs. According to the biochemical and physiological variations recorded on a long period of cultivation, R. indicum ‘Osakazuki’ reported the best performance. This azalea could be a valuable resource for breeders.  相似文献   
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Global efforts to reduce unwanted catches have led to the development of a vast array of by‐catch reduction devices (BRDs), in particular for mixed trawl fisheries. Some of these BRDs could likely benefit from being combined. However, the number of possible combinations would be prohibitive to be tested experimentally. Therefore, in this study we propose a meta‐analytical approach that combines the data available on BRDs tested independently in a fishery and predict the theoretical selectivity of all possible combinations of those devices. This allows to identify promising BRD combinations, worth experimental investigation and flexible trawl configurations, where the selectivity can be substantially modified by adding or removing one BRD, thus aiding fishermen in adapting to high variability in catch composition and quota availability. To illustrate the approach, we used BRDs developed for the well‐studied Nephrops (Nephrops norvegicus, Nephropidae) directed mixed trawl fishery in the Skagerrak and Kattegat seas. We predicted the selectivity of 100 BRD combinations for Nephrops, cod (Gadus morhua, Gadidae) and haddock (Melanogrammus aeglefinus, Gadidae), compared them in terms of absolute selectivity and performance under realistic catch scenarios, from both single‐ and multispecies perspectives, and identified 15 BRD combinations that could be worth future experimental investigation. The meta‐analytical approach makes best use of existing knowledge and leads to new insights about the potential for improvement and flexibility in trawl selectivity. This could benefit a variety of mixed trawl fisheries and help developing a new generation of more flexible gears, with multiple BRDs integrated in their structure.  相似文献   
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