Pharmacologic effects and detection methods of methylated analogs of fentanyl in horses

Pharmacologic effects of alpha-methylfentanyl and 3-methylfentanyl, analogs of fentanyl, were investigated in mares. The ability of an 125I-labeled fentanyl radioimmunoassay (125I-RIA) to detect these methylated fentanyl analogs in individual and pooled urine samples from horses was evaluated. Also, the ability of 7 fentanyl antibodies to react with fentanyl and fentanyl derivatives (sufentanil, alfentanil, and carfentanil) was investigated. Mares were studied in a locomotor test to determine the amount of stimulation methylated fentanyl analogs might induce. Two mares each were given alpha-methylfentanyl at 1, 2, 4, 8, or 13 micrograms/kg of body weight, IV, or 3-methylfentanyl at 0.4, 0.7, or 1 microgram/kg IV. The cross-reactivity of sufentanil, alfentanil, carfentanil, alpha-methylfentanyl, and 3-methylfentanyl with 7 fentanyl antibodies was studied, using the 125I-RIA. All fentanyl analogs, with the exception of alfentanil, cross-reacted well with a C1 antibody raised to fentanyl. Less satisfactory cross-reactivity was determined with 6 other antibodies raised to fentanyl derivatives. When the C1 antibody was combined with an iodinated analog to fentanyl, good detectability of alpha-methylfentanyl and 3-methylfentanyl, in terms of fentanyl equivalents, was obtained from urine samples of dosed mares. The ability of the 125I-RIA to detect methylated fentanyl analogs in forensic urine samples pooled in groups of up to 20 samples was evaluated. When these methylated analogs were administered to mares in doses that induced measurable locomotor stimulation, the analog's presence was readily detected in individual or pooled samples.     

波兰的森林认证

文中介绍了波兰的森林认证发展进程, 特别是森林认证体系, 森林认证现状及认证对林业的影响以及当前面临的问题和挑战, 对我国制定森林认证标准、建立森林认证体系、推动我国森林可持续经营具有一定的借鉴作用.     

利用重组自交系群体定位水稻柱头外露率QTL

水稻的柱头外露率影响异交结实率,不育系的柱头外露率则直接影响制种产量。本研究利用高柱头外露率的两系籼稻不育系1892S和低柱头外露率的籼稻品种‘扬稻6号选’构建的重组自交系群体(RILs),考查了F6和F7世代的柱头单外露率(SSE)、柱头双外露率(DSE)、柱头总外露率(TSE);采用基因分型测序技术(GBS)构建遗传连锁图谱,用复合区间作图法(CIM)共检测到了16个柱头外露率相关的QTLs,包括7个控制柱头单外露率的QTLs、4个控制柱头双外露率的QTLs、5个控制柱头总外露率的QTLs。这些QTLs分别位于第1、2、4、5、7和8染色体上,贡献率介于4.70%～18.00%。其中位于第1和4染色体上的QTLs在两年的试验中均被重复的检测到。这些检测到的QTLs为分子标记辅助选择培育高柱头外露率的不育系提供了基因资源。     

槲皮素对苎麻、涤纶的吸附性能初步研究

本文以生物黄酮配基槲皮素为分散染料,对苎麻分别在77℃乙醇染浴中和在93℃水染浴中进行了染色实验,并与合成纤维涤纶进行对比,为苎麻和涤纶用天然染料进行染色的工艺选择提出了初步方案。结果表明槲皮素是一种理想的环保天然分散染料。     

Feasibility for Building the Under-ground Sewage Treatment Plant in Chongqing City

With the development of the economy, the demand forhabitation is enhanced and the sewage and industrial waster water must be disposed before outlet. Today, most of the sewage treatment plants are built on the aboveground without discussing the underground. Therefore, by the comparative analysis of the property and cost of the underground sewage treatment plant and the ground, the underground sewage treatment plant have merits in save the city land and improvement environment.The Chongqing citypossess a lot of advantages in using the space of underground with the analysis of the physiognomy and geology condition of the Chongqing city. Therefore, the development of underground sewage treatment plant is feasible in the Chongqing city.     

An EOQ Model at Random when Average Demand Is a Linear Increasing Function

For certain types of inventory, the ordering cycle and demand may be random variants, which satisfy certain types distribution. The classical EOQ model usually neglects the fact. Based on the constant demand, under the hypothesis that the ordering cycle is a random variant which satisfies exponent distribution, average demand is a linear increasing function, this paper considers the effects of the time-value of capital and inflation on replenishment strategy of inventory system. Loosening the condition of basic economic order quantity model under deterministic state, the total cost function of the model is provided. The optimum order quantity and cycle are obtained. The application range of EOQ model under the constant demand is widened. The theoretical evidence is provided for the inventory system to make management decision.     

不同pH条件下罗非鱼肌肉蛋白分离效果及其功能特性的研究

利用pH调节法制备罗非鱼分离鱼蛋白.在临界pH条件下对罗非鱼肌肉蛋白进行处理得到肌肉溶解蛋白(Solution Muscle Protein,SMP),再利用等电点沉淀法对罗非鱼肌肉溶解蛋白进行分离得到肌肉分离蛋白(Isolated Muscle Protein,IMP),考查SMP的溶解率、黏度及IMP凝胶制品和常规中性漂洗(Conventional Wash)处理得到的蛋白凝胶制品的凝胶强度.以罗非鱼肌肉蛋白质在不同pH下的处理、转谷酰胺酶、食盐及凝胶化温度为因素,凝胶强度为目标参数进行正交试验设计.结果表明,与常规中性漂洗法相比, pH调节法制备的罗非鱼分离鱼蛋白具有回收效果好、功能性强的特点.     

氧化-生物双降解地膜对棉花生长影响及降解效果

研究氧化-生物双降解地膜对棉花生长的影响及降解效果,为氧化-生物双降解地膜代替普通聚乙烯地膜的可行性及推广应用提供理论参考。试验采用2种不同配方的氧化-生物双降解地膜,以普通聚乙烯地膜作为对照,分析不同降解地膜对棉花生长及产量的影响,观测增温保墒效果,明确降解性能。结果表明：2种降解地膜对棉花生育期、农艺性状、产量性状和纤维品质未产生显著影响,籽棉产量和增温保墒效果与普通地膜基本相同;诱导期为39 d的2018新疆阿拉尔棉花1号降解膜降解率达47.3 %,显著高于其他处理,具有较高的应用价值。     

大豆杂种优势高优势组合筛选及稳定性分析

经过1996－2000年5年的研究，共配制杂种优势测定组合199个，通过第一次产量鉴定表明，大豆具有明显的杂种优势，并筛选出F1超高亲，超对照优势率均为正值，且二者平均值大于10％的较强优势组合161个，占全部组合的80．9％，F1超高亲，超对照优势率均大于20％的高优势组合69个占全部组合的34％，并通过第二次产量鉴定进一步筛选出稳定的高优势组合4个，即合9661，9672，9731，97143，此外研究结果还表明，大豆杂种优势具有较好的稳定性，在不同年度，不同地点优势率变化不大，且趋势一致。