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861.
862.
Taylor A Dunne M Bennington S Ansell S Gardner I Norreys P Broome T Findlay D Nelmes R 《Science (New York, N.Y.)》2007,315(5815):1092-1095
We review the potential to develop sources for neutron scattering science and propose that a merger with the rapidly developing field of inertial fusion energy could provide a major step-change in performance. In stark contrast to developments in synchrotron and laser science, the past 40 years have seen only a factor of 10 increase in neutron source brightness. With the advent of thermonuclear ignition in the laboratory, coupled to innovative approaches in how this may be achieved, we calculate that a neutron source three orders of magnitude more powerful than any existing facility can be envisaged on a 20- to 30-year time scale. Such a leap in source power would transform neutron scattering science. 相似文献
863.
Schwartz T 《Science (New York, N.Y.)》2011,332(6025):35-6; author reply 36-7
864.
Cohen BE McAnaney TB Park ES Jan YN Boxer SG Jan LY 《Science (New York, N.Y.)》2002,296(5573):1700-1703
Electrostatics affect virtually all aspects of protein structure and activity and are particularly important in proteins whose primary function is to stabilize charge. Here we introduce a fluorescent amino acid, Aladan, which can probe the electrostatic character of a protein at multiple sites. Aladan is exceptionally sensitive to the polarity of its surroundings and can be incorporated site-selectively at buried and exposed sites, in both soluble and membrane proteins. Steady-state and time-resolved fluorescence measurements of Aladan residues at different buried and exposed sites in the B1 domain of protein G suggest that its interior is polar and heterogeneous. 相似文献
865.
Carbon and water flow between plants and the atmosphere is regulated by the opening and closing of minute stomatal pores in surfaces of leaves. By changing the aperture of stomata, plants regulate water loss and photosynthetic carbon gain in response to many environmental stimuli, but stomatal movements cannot yet be reliably predicted. We found that the complexity that characterizes stomatal control in seed plants is absent in early-diverging vascular plant lineages. Lycophyte and fern stomata are shown to lack key responses to abscisic acid and epidermal cell turgor, making their behavior highly predictable. These results indicate that a fundamental transition from passive to active metabolic control of plant water balance occurred after the divergence of ferns about 360 million years ago. 相似文献
866.
Late Miocene fossil hominid teeth recovered from Ethiopia's Middle Awash are assigned to Ardipithecus kadabba. Their primitive morphology and wear pattern demonstrate that A. kadabba is distinct from Ardipithecus ramidus. These fossils suggest that the last common ancestor of apes and humans had a functionally honing canine-third premolar complex. Comparison with teeth of Sahelanthropus and Orrorin, the two other named late Miocene hominid genera, implies that these putative taxa are very similar to A. kadabba. It is therefore premature to posit extensive late Miocene hominid diversity on the basis of currently available samples. 相似文献
867.
Blackburn TM Cassey P Duncan RP Evans KL Gaston KJ 《Science (New York, N.Y.)》2004,305(5692):1955-1958
The arrival of humans on oceanic islands has precipitated a wave of extinctions among the islands' native birds. Nevertheless, the magnitude of this extinction event varies markedly between avifaunas. We show that the probability that a bird species has been extirpated from each of 220 oceanic islands is positively correlated with the number of exotic predatory mammal species established on those islands after European colonization and that the effect of these predators is greater on island endemic species. In contrast, the proportions of currently threatened species are independent of the numbers of exotic mammalian predator species, suggesting that the principal threat to island birds has changed through time as species susceptible to exotic predators have been driven extinct. 相似文献
868.
Blau H Brazelton T Keshet G Rossi F 《Science (New York, N.Y.)》2002,298(5592):361-2; author reply 362-3
869.
Garner EC Bernard R Wang W Zhuang X Rudner DZ Mitchison T 《Science (New York, N.Y.)》2011,333(6039):222-225
Rod-shaped bacteria elongate by the action of cell wall synthesis complexes linked to underlying dynamic MreB filaments. To understand how the movements of these filaments relate to cell wall synthesis, we characterized the dynamics of MreB and the cell wall elongation machinery using high-precision particle tracking in Bacillus subtilis. We found that MreB and the elongation machinery moved circumferentially around the cell, perpendicular to its length, with nearby synthesis complexes and MreB filaments moving independently in both directions. Inhibition of cell wall synthesis by various methods blocked the movement of MreB. Thus, bacteria elongate by the uncoordinated, circumferential movements of synthetic complexes that insert radial hoops of new peptidoglycan during their transit, possibly driving the motion of the underlying MreB filaments. 相似文献
870.