Comparison of Cerebrospinal Fluid Pressure in Propofol-and Thiopental-anesthetized Eucapnic Dogs

Cerebrospinal fluid pressure (CSF_P) was measured as part of the neurologic assessment of dogs with suspected intracranial disease. Because propofol has not been shown to cause an increase in intracranial pressure in humans, the authors examined its effect on (CSF_P) in dogs to determine if it would be an appropriate substitute for thiopental as an anesthetic agent for the measurement of CSF_P. The CSF pressure in eucapnic propofol-anesthetized dogs (105 ± 5.6 mm H_PO) was not significantly different (p < .05) from CSF_P in eucapnic thiopental-anesthetized dogs (103.8 ± 6.6 mm H_PO).     

CGA-72662—A new sheep blowfly insecticide

SUMMARY The efficiency of 2-cyclopropylamino-4, 6-diamino-s-triazine CGA-72662 (proposed common name: cyromazine) for the control of blowfly strike was tested in fly cage and field trials on sheep. The safety to sheep and physico-chemical properties of the compound as they relate to blowfly control were also assessed.     

Antibacterial activity of marbofloxacin. A new fluoroquinolone for veterinary use against canine and feline isolates

Marbofloxacin is a new fluoroquinolone developed exclusively for veterinary use. Minimum inhibitory concentrations of marbofloxacin were assessed for 816 recent isolates associated with canine or feline diseases. Marbofloxacin showed a broad spectrum of activity against gram-negative and gram-positive bacteria. In vitro rates of killing of marbofloxacin and enrofloxacin were compared against strains of Staphylococcus intermedius and Pasteurella multocida , and the results showed no marked difference between the two antibiotics. The duration of bactericidal activity was evaluated ex vivo in the urine of dogs and cats treated with marbofloxacin and lasted from 2 to 5 days after a single administration according to the dosages. Post-antibiotic effect durations were determined with Escherichia colt, PasteureUa multocida, Staphylococcus aureus and Staphylococcus intermedius and were found almost equal to those of enrofloxacin or ciprofloxacin. These results predict a great potential for marbofloxacin in the treatment of a wide range of diseases in dogs and cats.     

Rose mosaic disease: symptoms induced in roses by graft inoculation with both prunus necrotic ringspot and apple mosaic viruses

Symptoms induced in rose by single isolates of the cherry serotype of prunus necrotic ringspot virus (PNRSV) and an apple serotype (apple mosaic virus; ApMV) were characteristically different, and appeared at different times throughout the growing season according to the ambient temperature. These features remained discrete, even in roses infected by both viruses and were shown by immunospecific electron microscopy to be a reliable indication of infection by either virus.
However, cross-protection between the two isolates was not reciprocal; mixed infections were established only when roses were simultaneously graft-inoculated with ApMV and PNRSV, or when PNRSV-infected roses were supei-infected with ApMV. The significance of these results in relation to the possible natural occurrence of mixed infections in rose or of isolates of intermediate serotype is discussed.     

A field evaluation of the efficacy of tolfenamic acid and oxytetracycline in the treatment of bovine respiratory disease

Deleforge, J., Thomas, E., Davot, J.L., Boisrame, B. A field evaluation of the efficacy of tolfenamic acid and oxytetracycline in the treatment of bovine respiratory disease. J. vet. Pharmacol Therap. 17,43–47.
In ablinded multicentre trial 313 cattle showing clinical signs of respiratory disease were allocated randomly into three groups, treated intramuscularly with a long-acting oxytetracycline formulation at a dose rate of 20 mg/kg bodyweight in combination with vehicle alone (placebo) or with tolfenamic acid at 2mg/kg, bodyweight once or on two occasions with a 48-h interdosing interval. The clinical status of the animals was monitored for 5 days using a specific scoring system and weight gain was calculated between day 0 and day 21. Relapses were monitored from day 5 until day 21. When oxytetracycline was combined with two injections of tolfenamic acid, there was a significant (P < 0.04) improvement in the clinical resolution. This regimen also produced non-significant improvements in cure rate, reduced frequency of relapses and improved weight gain.     

Producer Services Development and the Role of Telecommunications: A Case Study in Rural Washington

Information-intensive producer services, which constitute one of the fastest growing components of the U.S. economy, have been identified as a potential contributor to economic development in rural areas. This issue is examined in a case study of a community in rural Washington State. The findings indicate that producer services have not been decentralizing to rural Washington, and that opportunities for producer services development in rural communities are limited because of the inaccessibility of markets, smaller pools of skilled labor, and the lack of agglomeration economies. Opportunities for producer services are greatest in large rural communities with high-quality telecommunications systems. Although the quality of telecommunications systems is important to the economic health of communities, advances in telecommunications can be a two-way street for rural America. While telecommunications improvements increase a rural community's access to information and make it possible for rural businesses to more easily serve non-local markets, they can also make it easier for firms located in urban areas to serve rural markets via branch offices or through the telecommunications system.     

An Open Patch-Graft Technique for Correction of Pulmonic Stenosis in the Dog

An open patch-graft technique for correction of pulmonic stenosis was performed in four dogs. A synthetic patch-graft was presutured to a partial-thickness incision in the right ventricular outflow tract and to the pulmonary artery along its cranial border. The pulmonary artery and right ventricle were incised during venous inflow occlusion, and dysplastic pulmonic valve leaflets were excised. The arteriotomy was closed by suturing the caudal margin of the incision to the patch-graft. The entire procedure was performed during mild hypothermia (30 degrees - 32 degrees C). The mean circulatory arrest time was 5.5 +/- 0.2 minutes. The mean systolic pressure gradient across the pulmonic valve before surgery was 121 +/- 29 mm Hg; after surgery it was 9 +/- 2 mm Hg.