Plants from Iryanthera genus have been traditionally used as food supplements by South American Indians. The MeOH extract of leaves of Iryanthera juruensis, one of the plants endemic to the Amazon region and consumed in Brazil, and the hexane extract from its seeds inhibited lipid peroxidation (LPO) and cyclooxygenase (COX-1 and -2)) enzymes in in vitro assays. Further analyses of these extracts yielded 5-deoxyflavones (1-5) from the leaf extract and sargachromenol (6), sargaquinoic acid (7), a novel juruenolic acid (8), omega-arylalkanoic acids (9a-c), and the lignan guaiacin (10) from the seed extract. Compounds 3-5 inhibited LPO by 86%, 77%, and 88% at 10 ppm, respectively, and compounds 6 and 9a-c showed inhibition at 76% and 78% at 100 ppm, respectively. However, compounds 7 and 8 were inactive and lignan 10 exhibited LPO inhibitory activity by 99% at 100 ppm compared to commercial antioxidants butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), and vitamin E. The flavones 1-5 also inhibited COX-1 and -2 enzymes by 50-65% at 100 ppm. Compound 6 showed high but nonselective inhibition of COX-1 and COX-2 enzymes, when compared to aspirin and Celebrex, a nonsteroidal anti-inflammatory drug (NSAID). Compounds 7 and 10 inhibited COX-1 by 60% and 65% and COX-2 by 37% and 18%, respectively, whereas compounds 8 and 9a-c showed little or no activity against these enzymes. 相似文献
The coffee berry borer, Hypothenemus hampei (Ferrari), is an important devastating coffee pest worldwide. Both trypsin and chymotrypsin enzyme activities from H. hampei larval midgut can be inactivated by proteinaceous enzyme-inhibitors. A serine proteinase inhibitor belonging to the Bowman-Birk class was purified from a wild accession of Phaseolus coccineus L. seeds. The inhibitor (PcBBI1) is a cysteine-rich protein that is heat-stable at alkaline pH. MALDI-TOF/MS analysis showed that PcBBI1 occurs in seeds as a monomer (8689 Da) or dimer (17,378 Da). Using in vitro inhibition assays, it was found that PcBBI1 has a high inhibitory activity against H. hampei trypsin-like enzymes, bovine pancreatic chymotrypsin, and trypsin. According to this, PcBBI1 could be a promising tool to make genetically modified coffee with resistance to coffee berry borer. 相似文献
Agroforestry Systems - The potential of agroforestry systems (AFS) for atmospheric carbon sequestration in degraded tropical lands is of key interest for climate change and rural development... 相似文献
Journal of Pest Science - Increasing either inter- or intraspecific plant diversity has shown the potential to engender bottom-up and top-down effects upon herbivorous pests. Nonetheless, because... 相似文献
Agroforestry Systems - The use of native trees in agroecosystems is a promising way to increase litter deposition and nutrient cycling and foster the recovery of degraded areas, especially in... 相似文献
Agroforestry Systems - Inland waters such as streams that receive carbon from terrestrial landscapes usually have a net heterotrophic metabolism and emit significant amounts of CO2 to the... 相似文献
Precision Agriculture - Defining the ideal soybean stand is essential for obtaining maximum grain yield. As a hypothesis of the work, it was questioned whether it is possible to vary seeding... 相似文献
Fish Physiology and Biochemistry - The present study was carried out to evaluate the genotoxic potential of nutritional quality of feed, using erythrocytic nuclear abnormalities assay in Nile... 相似文献
Use of geographical information systems (GIS) in inland fisheries has hitherto been essentially restricted to site evaluation for aquaculture development and assessment of limnological changes in time and space in individual water bodies. The present GIS study was conducted on the land-use pattern of the catchments of nine reservoirs in Sri Lanka, for which detailed fishery data, viz. yield, fishing intensity, landing size of major constituent species, together with selected limnological data such as conductivity and chlorophyll- a , were available. Potential statistical relationships (linear, curvilinear, exponential and second-order polynomial) of fish yield ( FY , in kg ha−1 yr−1) to different land-use patterns, such as forest cover ( FC , in km2) and shrub-land ( SL , in km2), either singly, or in combination, and/or the ratio of each land type to reservoir area ( RA in km2) and reservoir capacity ( RC in km3), were explored. Highly significant relationships were evident between FY to the ratio of SL and/or FC + SL to RA and/or RC . Similarly, the above land-use types to RA and RC ratios were significantly related to limnological features of the reservoirs. The relationships of FY to various parameters obtained in this study were much better correlated than those relationships of FY to limnological and biological parameters used in yield prediction in tropical and temperate lacustrine waters previously. 相似文献
The development and intensification of Nile tilapia farming systems has happened together with ever increased use of antibiotics and therapeutants. Research on the use of probiotics has come along as alternative to routine use of antibiotics in fish diets. The manipulation of the gut microbiota through dietary probiotic inclusion targeting improved growth rate and disease resistance has been investigated in many farmed fish species. However, mechanisms underlying modulation of fish immune response remains unclear. This review summarizes and discuss recent findings in the role of probiotics on the immunity of Nile tilapia Oreochromis niloticus addressing available information regarding immunological parameters such as phagocytic activity, lysozyme, respiratory burst activity, antioxidant enzymes, complement system as well as immune-related gene expression, in the aim to foster research efforts on effective strategies for the successful use of probiotics in the tilapia farming industry.