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排序方式: 共有69条查询结果,搜索用时 31 毫秒
51.
Takaharu Itami Hiroko Aida Makoto Asakawa Yoko Fujii Tomoya Iizuka Ayako Imai Toshie Iseri Tomohito Ishizuka Kei Kakishima Masatoshi Kamata Takako Miyabe-Nishiwaki Shotaro Nagahama Kiyokazu Naganobu Ryohei Nishimura Shozo Okano Tadashi Sano Kazuto Yamashita Yoshiki Yamaya Masashi Yanagawa 《Veterinary anaesthesia and analgesia》2017,44(3):461-472
Objective
To explore the major risk factors linking preoperative characteristics and anaesthesia-related death in dogs in referral hospitals in Japan.Study design
Observational cohort study.Animals
From April 1, 2010 to March 31, 2011, 4323 dogs anaesthetized in 18 referral hospitals in Japan.Methods
Questionnaire forms were collated anonymously. Death occurring within 48 hours after extubation was considered as an anaesthesia-related death. Patient outcome (alive or dead) was set as the outcome variable. Preoperative general physical characteristics, complete blood cell counts, serum biochemical examinations and intraoperative complications were set as explanatory variables. The risk factors for anaesthesia-related death were evaluated using chi-square test or Fisher's exact test, followed by multivariable logistic regression analysis of the data. Significance was set at p < 0.05.Results
Thirteen dogs that died from surgical error or euthanasia were excluded from statistical analysis. The total mortality rate in this study was 0.65% [28/4310 dogs; 95% confidence interval (CI), 0.41–0.89]. Furthermore, 75% (95% CI, 55.1–89.3) of anaesthesia-related deaths occurred in dogs with pre-existing diseases. Most of the deaths occurred postoperatively (23/28; 82.1%; 95% CI, 63.1–93.9). Preoperative serum glucose concentration <77 mg dL–1 (6/46; 13.0%; 95% CI, 4.9–26.3), disturbance of consciousness (6/50; 12.0%; 95% CI, 4.5–24.3), white cell count >15,200 μL–1 (16/499; 3.4%; 95% CI, 1.9–5.5) and American Society of Anesthesiologists grade III–V (19/1092; 1.7%; 95% CI, 1.1–2.7) were identified as risk factors for anaesthesia-related death. Intraoperative hypoxaemia (8/34; 23.5%; 95% CI, 10.7–41.2) and tachycardia (4/148; 2.7%; 95% CI, 0.7–6.8) were also risk factors for anaesthesia-related death.Conclusions and clinical relevance
The results revealed that certain preoperative characteristics were associated with increased odds of anaesthesia-related death, specifically low serum glucose concentration and disturbances of consciousness. Greater attention to correcting preanaesthetic patient abnormalities may reduce the risk of anaesthesia-related death. 相似文献52.
Shozo H. Sugiura Victor Raboy Kevin A. Young Faye M. Dong Ronald W. Hardy 《Aquaculture (Amsterdam, Netherlands)》1999,170(3-4):285-296
Approximately two-thirds of phosphorus in various grains is present as phytate, which is not well-utilized by fish and other monogastric species. Besides its low availability of phosphorus, phytate is reported to reduce the availability of other dietary nutrients to animals. Single-gene, non-lethal low phytic acid (lpa) mutations in corn and barley cause the seed to store most of the phosphorus as inorganic phosphorus instead of as phytate phosphorus. Theoretically, using these mutant grains containing lower levels of phytate in animal feeds should reduce phosphorus excretion by the animals, provided that available phosphorus levels in feeds containing these grains are appropriately adjusted downward. This study was conducted as a first step to determine if the biological availability of phosphorus in the low-phytate mutants of barley, dent corn and flint corn differed significantly from that in ordinary grains for fish. Also of interest was the effect, if any, on the availability of other minerals in formulated feeds containing the low-phytate grains. Feeding trials demonstrated that the apparent availability of phosphorus in low-phytate grains was significantly higher than that in ordinary grains when they were combined with low-ash ingredients. Fecal phosphorus content (on average) decreased 50.2% (in phytate-phosphorus) or 42.9% (in total phosphorus) by replacing ordinary grains with low-phytate grains in the low-ash diets. The apparent availabilities of calcium, iron, zinc and strontium also were significantly higher in the low-ash diet containing low-phytate dent corn than that containing ordinary dent corn. However, no such increase was observed with low-phytate barley or low-phytate flint corn over their counterpart grains in either calcium, iron or zinc. The apparent availabilities of copper, manganese, magnesium, potassium and sodium were not significantly different between ordinary and low-phytate grains. The apparent digestibility of dry matter also was not significantly different between ordinary and low-phytate grains. The results of this study suggest that a substantial reduction of phosphorus discharge from fish, poultry and animal farms could be achieved simply by replacing ordinary grains with low-phytate mutant grains in low-ash feeds. 相似文献
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55.
Kensuke Furuta Kotaro Nishi Chun-Ho Park Kenichi Maeda Satomi Iwai Iwao Sakonjyu Kazunori Saigami Shozo Okano 《The Canadian veterinary journal. La revue veterinaire canadienne》2021,62(11):1181
A 7-month-old castrated French bulldog was presented with a left-sided mandibular tumor. The initial tumor biopsy diagnosis was ameloblastoma. The owner brought this dog the Kitasato University Veterinary Teaching Hospital for more detailed examination and treatment. Computed tomography revealed a tumor on the left lateral mandibular gingiva from the caudal third of the incisor tooth to the right canine tooth, associated with severe amorphous osteolysis of the mandibular bone. The tumor was surgically excised and diagnosed as papillary squamous cell carcinoma. Currently, 2514 d (6.9 y) since the operation, the dog is healthy, without recurrence.Key clinical message:Although papillary squamous cell carcinoma is rare, many cases have been reported in the oral cavity of medium-to large-sized dogs. Based on this report, papillary squamous cell carcinoma can occur in small dogs such as young French bulldogs and a good prognosis can be achieved with proper resection. 相似文献
56.
Young Tae PARK Shozo OKANO 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2015,77(10):1223-1226
We investigated the influence of pneumoperitoneum#(PP) and postural change under
inhalation anesthesia with isoflurane, which is routinely used in dogs, on the
cardiovascular and respiratory systems. As test animals, 6 adult beagles were used. To
induce anesthesia, atropine, butorphanol and propofol were intravenously injected.
Anesthesia was maintained with 1.3 MAC (1.7%) isoflurane. The following were the
experiment conditions: I:E ratio, 1:1.9; tidal air exchange, 20 ml/kg;
and ventilation frequency, 14 times/min. Respiration was regulated so that the
PaCO2 was approximately 35 to 40 mmHg before the start of the experiment. PP
with CO2 (intraperitoneal pressure 15 mmHg) and a postural change (15°C) was
performed during the experiment. As parameters of circulatory kinetics, heart rate (HR),
mean aortic pressure (MAP), mean pulmonary arterial pressure (MPAP), central venous
pressure (CVP), femoral venous pressure (FVP) and cardiac output (CO) were measured. As
parameters of respiratory kinetics, airway pressure (PAW) and blood gas (BG) were
measured. There were significant increases in HR, MAP, MPAP, CVP, FVP, CO, PAW and
PaCO2 after PP in the horizontal position. There were significant increases
in CVP, FVP, PAW and PaCO2 after PP in the Trendelenburg position. There were
significant increases in the MPAP, CVP, FVP, PAW and PaCO2 after PP in the
inverse Trendelenburg position. There was a significant difference in FVP after PP between
the Trendelenburg position and inverse Trendelenburg position. The results of this
experiment suggest that appropriate anesthesia control, such as changing the ventilation
conditions after PP, is required for laparoscopic surgery under inhalation anesthesia with
isoflurane. 相似文献
57.
Akiko Sasaki Shozo Shikenya Kazuhiko Takeda Takayuki Nakatsubo 《Journal of Forest Research》2007,12(1):68-74
To estimate the importance of leaching of dissolved organic matter (DOM) as a pathway through which organic matter is supplied
to stream ecosystems, we examined the amount of leachate over time and chemical properties of DOM leached from leaves in different
conditions. The samples used were green leaves, yellow senescent leaves, and leaf litter of Salix gracilistyla Miq., which is the dominant riparian plant species in the middle reaches of rivers in western Japan. We analyzed dissolved
organic carbon (DOC), total sugar, and polyphenol in the leachate of leaf samples collected from a fluvial bar in the middle
reaches of the Ohtagawa River in Hiroshima Prefecture, Japan. Considerable leaching of DOC from senescent leaves [37.3 mg g−1 dry weight (dw) leaf] and leaf litter (8.1 mg g−1 dw leaf) occurred within 24 h after immersion. In contrast, DOC leached from green leaves was negligible until 1 week after
leaf immersion. Carbon loss of leaves by leaching within 24 h after leaf immersion was estimated to be less than 8%, suggesting
that leaching of DOC from S. gracilistyla leaves is a minor pathway through which organic matter is supplied to stream ecosystems. DOM leached from the leaves included
sugar and polyphenol, which were among the major chemical forms of DOM leached from the leaves (based on the molecular mass).
In a laboratory experiment in which the difference in the stability of DOM between the chemical forms was examined, sugar
decomposed more rapidly than polyphenol. 相似文献
58.
对来源于世界9个国家和地区的92个栽培大麦品种的染色体N带带型作了比较分析,发现N带带型存在多态性。 相似文献
59.
60.
Sato M Tokuji Y Yoneyama S Fujii-Akiyama K Kinoshita M Ohnishi M 《Journal of agricultural and food chemistry》2011,59(19):10723-10731
To compare and estimate the effects of dietary intake of three kinds of mushrooms (Pleurotus ostreatus, Grifola frondosa, and Hypsizigus marmoreus), mice were fed a diet containing 10-14% of each mushroom for 4 weeks. Triacylglycerol in the liver and plasma decreased and plasma cholesterol increased in the P. ostreatus-fed group compared with those in the control group. Cholesterol in the liver was lower in the G. frondosa-fed group than in the control group, but no changes were found in the H. marmoreus-fed group. DNA microarray analysis of the liver revealed differences of gene expression patterns among mushrooms. Ctp1a and Fabp families were upregulated in the P. ostreatus-fed group, which were considered to promote lipid transport and β-oxidation. In the G. frondosa-fed group, not only the gene involved in signal transduction of innate immunity via TLR3 and interferon but also virus resistance genes, such as Mx1, Rsad2, and Oas1, were upregulated. 相似文献