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Chondrodysplasia in Australian Dexter cattle 总被引:1,自引:0,他引:1
Objective To describe the occurrence of chondrodysplasia in Australian Dexter cattle.
Design A pathological and genetic case report.
Procedure Congenital lethal chondrodysplasia was studied in two female Dexter foetuses aborted mid to late gestation. Clinicopathological findings including histological changes in limb bones, and analysis of pedigree information were evaluated.
Results Characteristic features of congenital lethal chon-drodysplasia (Dexter bulldog) include abortion, disproportionate dwarfism, a short vertebral column, marked micromelia, a relatively large head with retruded muzzle, cleft palate and protruding tongue and a large abdominal hernia. Histological changes in limb bones are consistent with failure of endochondral ossification. Dexter chondrodysplasia is considered to be inherited in an incompletely dominant manner with the homozygous form producing the congenital lethal condition. A preliminary minimum estimate of heterozy-gote frequency is 19% within the registered Australian Dexter herd, based on analysis of the contribution of three obligate heterozygotes whose semen has been widely used by artificial insemination in Australia.
Conclusion Dexter chondrodysplasia is present in Australian cattle and further cases of the homozygous form, congenital lethal chondrodysplasia, are likely to occur.
Recommendation It is requested that spleen and liver tissue from bulldog foetuses and blood from their parents be collected to assist research into Dexter chondrodysplasia. 相似文献
Design A pathological and genetic case report.
Procedure Congenital lethal chondrodysplasia was studied in two female Dexter foetuses aborted mid to late gestation. Clinicopathological findings including histological changes in limb bones, and analysis of pedigree information were evaluated.
Results Characteristic features of congenital lethal chon-drodysplasia (Dexter bulldog) include abortion, disproportionate dwarfism, a short vertebral column, marked micromelia, a relatively large head with retruded muzzle, cleft palate and protruding tongue and a large abdominal hernia. Histological changes in limb bones are consistent with failure of endochondral ossification. Dexter chondrodysplasia is considered to be inherited in an incompletely dominant manner with the homozygous form producing the congenital lethal condition. A preliminary minimum estimate of heterozy-gote frequency is 19% within the registered Australian Dexter herd, based on analysis of the contribution of three obligate heterozygotes whose semen has been widely used by artificial insemination in Australia.
Conclusion Dexter chondrodysplasia is present in Australian cattle and further cases of the homozygous form, congenital lethal chondrodysplasia, are likely to occur.
Recommendation It is requested that spleen and liver tissue from bulldog foetuses and blood from their parents be collected to assist research into Dexter chondrodysplasia. 相似文献
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Luc Raymond Bruce Schaffer Jeffrey K. Brecht Edward A. Hanlon 《Journal of plant nutrition》2013,36(5):871-889
Internal breakdown in mango fruit is a disorder often attributed to a nutrient deficiency, particularly of calcium (Ca), in the fruit. The relationship between internal breakdown in mango fruit and fruit mineral element concentrations and fresh weight was investigated. Fruit were collected weekly from a commercial orchard beginning 4 weeks after fruit set (WAFS) until the fruit were ripe. The concentrations of nitrogen (N), phosphorus (P), potassium (K), Ca, magnesium (Mg), zinc (Zn), copper (Cu), manganese (Mn), iron (Fe), and boron (B) and fresh weight of ‘Tommy Atkins’ mango fruit with and without internal breakdown were compared. Disordered fruit weighed more than healthy fruit 4 WAFS. However, when fruit were ripe there were no significant differences in fruit weight between healthy and disordered fruit. Disordered fruit contained significantly higher concentrations of N, P, Ca, and B than the healthy mango fruit, 4 WAFS. When fruit were ripe, there were no differences in N, K, Ca, Mg, Zn, Mn, Fe, and B concentrations between healthy and disordered fruit. Ripe, healthy fruit had higher Cu and lower P concentrations than ripe, disordered fruit. Internal breakdown could not be specifically linked to a Ca deficiency in mango fruit at any stage of fruit ontogeny. 相似文献
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Urinary catheterisation of female dogs: a comparison between three techniques for catheter placement
AE Tipler EA Moses R Greer P Delisser BD McCracken PA Moses 《Australian veterinary journal》2020,98(8):364-370
The objective of this study was to describe a new technique for urinary catheterisation of female dogs using a novel catheterisation device (NCD) and to compare the time taken to place a catheter using this technique with traditional techniques. A secondary objective was to survey participants on which of the techniques they preferred. Female canine cadavers of varying sizes were utilised and veterinary students who had not previously placed a urinary catheter were enrolled. Each participant performed three catheterisation techniques, Visual with speculum (SPEC), Blind Palpation (BP) and catheterisation with NCD on three sizes of dog. Time required using each technique was compared using Kaplan–Meier plots and mixed models Cox Proportional Hazards regression. Median times to catheterisation were 300 s (IQR 261–417 s) with the SPEC method, 420 s (IQR 253–545 s) with the NCD method and 725 s (574–1032s) with the BP method. Both SPEC and NCD methods were significantly faster compared to the BP method, with Hazard Ratios of 3.66 (95% CI 1.94–6.91, P < 0.001) and 3.57 (95% CI 1.87–6.81, P < 0.001), respectively. Six of nine participants found the NCD the easiest technique, 5/9 of the participants found the palpation technique most difficult and 4/9 found the speculum technique most difficult. BP appears to be the technique of least preference and increased time requirement. The novel urinary catheterisation device may provide a simpler method of visualisation of the urethral papilla and may provide a more sterile way of placing the catheter, although further investigation is needed to confirm this. 相似文献
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Nicolas P Mäder U Dervyn E Rochat T Leduc A Pigeonneau N Bidnenko E Marchadier E Hoebeke M Aymerich S Becher D Bisicchia P Botella E Delumeau O Doherty G Denham EL Fogg MJ Fromion V Goelzer A Hansen A Härtig E Harwood CR Homuth G Jarmer H Jules M Klipp E Le Chat L Lecointe F Lewis P Liebermeister W March A Mars RA Nannapaneni P Noone D Pohl S Rinn B Rügheimer F Sappa PK Samson F Schaffer M Schwikowski B Steil L Stülke J Wiegert T Devine KM Wilkinson AJ van Dijl JM Hecker M Völker U Bessières P 《Science (New York, N.Y.)》2012,335(6072):1103-1106