GHRH可以提高猪抗肺炎霉形体感染能力

目前．动物的呼吸道疾病仍然是一个严重的问题．特别是由肺炎霉形体（Mhyo）引起的肺炎占有较大的比例。Mhyo是地方性肺炎的病原体．可以引起慢性肺炎以及其他细菌感染。此外．存在猪繁殖与呼吸道综合征（PRRS）病毒还可以显著降低Mhyo菌苗接种的效果。Mhyo感染不仅给养猪业造成很大的经济损失．而且带来严重的动物福利问题。最近研究证实．生长激素释放激素（GHRH）和生长激素（GH）具有免疫调节功能。     

微量元素对猪营养作用研究最新进展

微量元素是动物饲料中被人们普遍忽视的营养成分，人们对其生理作用往往估计不足，并认为在饲料中不会缺乏微量元素。微量元素对于维持机体功能以及保持最佳生长、繁殖和免疫反应都不可缺少，缺乏微量元素可以引起动物性能的大幅度降低。本文介绍了微量元素对猪营养作用研究的最新进展。[第一段]     

国外动物疫病传入途径、危害与控制

长期以来．动物疫病在全世界传播．对人类健康和畜牧业发展造成了严重的危害和广泛的影响。防止国外动物疫病传人已经成为摆在我们面前的重大课题。[第一段]     

动物保健品进口与使用的风险、影响及防控对策

经过长达15年马拉松式的艰苦谈判,2001年12月11日,我国终于加入了世界贸易组织(WTO)。我国加入WTO五年,在方方面面的共同努力下,比较平稳地度过了“过渡期”和“后过渡期”。但是,“后过渡期”后,我国对主要产业的“过渡期”保护将到期,对外开放水平与市场开放力度和范围将超过以往,深度融入全球经济体系。面对我国广阔而又开放的市场,国外动物保健品企业将会进一步加大挺进的力度。由于国外动物保健品也是鱼龙混杂,良莠不齐,若缺乏防范或防范不到位,盲目扩大进口与使用,极有可能使一些具有风险的产品闯进我国国门,威胁我国畜牧业的健康发展。居安思危,增强防范意识,加大防范措施,不容丝毫松懈。     

日粮添加天冬氨酸镁可提高猪肉质量

猪的屠宰前管理可能影响猪肉质量。屠宰前急性应激可能会加快死后酸化速度而引起PSE肉,慢性应激则可能会使肌糖原在屠宰前排空而导致DFD肉。在澳大利亚,PSE和DFD肉的平均发生率分别为32％和15％,每年使养猪业损失达2000万美元。据报道,给猪的日粮中添加镁可以降低血浆中皮质醇和儿茶酚胺浓度,从而减轻应激的影响。本试验是在研究在日粮中添加天冬氨酸镁(MgAsp)是否可以用于提高猪肉的质量。     

The effect of topical tripeptide-copper complex on healing of ischemic open wounds

OBJECTIVE: To evaluate the effects of topical glycyl-L-histidyl-L-lysine tripeptide-copper complex (TCC; Iamin 2% Gel; Procyte Corporation, Redmond, WA) on healing in ischemic open wounds. STUDY DESIGN: Experimental study. SAMPLE POPULATION: Twenty-four adult male Sprague-Dawley rats. METHODS: Rats were divided into 3 groups: topical TCC, topical TCC vehicle (hydroxypropyl-methylcellulose), and no treatment (control). Six-mm-diameter, full-thickness wounds were created within an ischemic bipedicle skin flap on the dorsum of each rat. Each day, for 13 days, wound margins were traced, and the TCC and TCC vehicle groups were treated topically. Tracings were scanned, and wound perimeter and area were calculated. On days 6, 10, and 13, selected wounds were biopsied and analyzed for tumor necrosis factor alpha (TNF-alpha) and matrix metalloproteinases (MMP) 2 and 9. RESULTS: A significant decrease in wound area was seen in the TCC group, but not the vehicle group, when compared with the control group on days 3 to 5, 6 to 9, and 11 to 13 and when TCC was compared with TCC vehicle on days 3 and 9. On day 13, initial wound area had decreased by 64.5% in the TCC group, 45.6% in the vehicle group, and 28.2% in the control group. On days 6, 10, and 13, TCC-treated wounds contained significantly lower concentrations of TNF-alpha and MMP-2 and MMP-9 than control wounds. CONCLUSION: Topical TCC resulted in accelerated wound healing in ischemic open wounds. CLINICAL RELEVANCE: Topical TCC is an effective stimulant of healing of ischemic open wounds in rats and may have an application for the treatment of chronic wounds in other species. Clinical evaluation of topical TCC is warranted.     

FB1对肉鸡免疫系统的影响

家禽日粮中的植物源性饲料容易受到霉菌毒素的污染,大量采食后可导致病理综合征,引起霉菌毒素中毒,造成严重的经济损失,霉菌毒素种类繁多,其中,烟曲霉毒素(Fumonisin)B1(FB1)是一种最近发现的由一些镰刀菌产生的霉菌毒素.已经证实,这种霉菌毒素与马脑白质软化病和猪肺水肿有关,对小鼠有致癌作用,并与人的食道癌有关.     

The effect of a porcine-derived small intestinal submucosa product on wounds with exposed bone in dogs

OBJECTIVE: To determine the effect of a porcine-derived small intestinal submucosa product (PSIS) on healing time, epithelialization, angiogenesis, contraction, and inflammation of wounds with exposed bone on the distal aspect of the limbs of dogs. STUDY DESIGN: Prospective, controlled, experimental study. ANIMAL POPULATION: 10 young adult, purpose-bred, male Beagles. METHODS: Small wounds with exposed bone were created on the lateral aspect of metatarsal V and the medial aspect of metatarsal II on both hindlimbs. Three sheets of PSIS were sutured into the wounds of the treated limb, and the other limb served as a control. On day 10, punch biopsies of the medial metatarsal wounds were collected and were evaluated microscopically after routine hematoxylin and eosin and phosphotungstic acid hematoxylin (PTAH) staining. The lateral metatarsal wounds were evaluated by planimetry and laser Doppler perfusion imaging on days 7, 14, and 21. Time until complete wound healing was also recorded. The level of significance was set at P < or =.05 for all statistical analyses. RESULTS: Laser Doppler perfusion measurements were significantly higher in control wounds on day 7, but no differences were noted on days 14 and 21. No significant differences in planimetric values, histopathologic appearance, or time until complete wound healing were noted among treated and control groups. CONCLUSIONS: No objective differences in healing were noted between control wounds and wounds treated with PSIS. CLINICAL RELEVANCE: There appears to be no contraindication to the use of PSIS on clean wounds with exposed bone on the distal limbs of dogs. However, our objective data provides no evidence that this product affects epithelialization, contraction, or time to complete healing in wounds with exposed bone.     

Use of a particulate extracellular matrix bioscaffold for treatment of acquired urinary incontinence in dogs

OBJECTIVE: To evaluate use of a particulate bioscaffold consisting of the extracellular matrix (ECM) of the urinary bladder from pigs for treatment of acquired urinary incontinence in dogs resistant to medical treatment. DESIGN: Case series. ANIMALS: 9 female dogs with acquired urinary incontinence. PROCEDURE: In 6 dogs, 30 mg of particulate ECM in 1.0 mL of a carrier consisting of glycerin and saline 10.9% NaCI) solution was injected into each of 3 equally spaced sites around the circumference of the internal urethral sphincter via an endoscopic technique. In the remaining 3 dogs (control dogs), 1.0 mL of the carrier alone was injected in 3 equally spaced sites around the circumference of the internal urethral sphincter in a similar manner. RESULTS: For dogs treated with the ECM, median duration of urinary continence following treatment was 168 days (range, 84 to 616 days), whereas for the control dogs, median duration of urinary continence following the procedure was 14 days (range, 7 to 31 days). Two of the 3 control dogs were treated with the ECM at the end of the study and were continent for 119 and 252 days. No adverse effects were observed in any dog. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that endoscopically guided injection of particulate ECM into the internal urethral sphincter may be useful for the treatment of acquired urinary incontinence in female dogs.     

β-胡萝卜素对奶牛繁殖性能的影响

近几年来,高产奶牛产后不发情或屡配不孕等繁殖问题日益突出,对奶牛养殖效益影响很大。据调查统计,约有20％～40％的奶牛存在繁殖障碍,位居奶牛3大常见病之首。提高奶牛繁殖性能已成为重中之重。在对策研究中,β-胡萝b素对奶牛繁殖性能的影响引起了人们的关注。