Contribution of lipoprotein lipase activity to the differential growth of three adipose tissue depots in young broiler chickens

1. The growth of three distinct adipose tissue depots around the abdomen, neck and thigh was measured in a commercial strain of broiler, and related to the changes in activity of lipoprotein lipase within each depot.

2. At 10 d of age there was no significant difference between the weights of the depots. Thereafter the abdominal fat pad exhibited a much greater rate of growth than the other two depots so that by 55 d of age the abdominal fat pad was 4 times the size of the leg depot and 3.4 times the size of the neck depot.

3. Changes in total lipoprotein lipase activity for all three depots showed a similar pattern to the changes in their weight.

4. When [¹⁴C]‐VLDL was injected intravenously into birds at 15 and 57 d of age the percentage taken up into the abdominal fat pad was greater than that into the other two depots at both ages. At 57 d of age the abdominal fat pad had a 2.3‐fold greater uptake than at 15 d whereas the other two depots showed no significant differences at the two ages.

5. These results provide further evidence for a key role of lipoprotein lipase in regulating adipose tissue growth in broilers. They also demonstrate that although the abdominal fat pad has been used in a number of studies of adipose tissue metabolism it is not necessarily representative of other depots.