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排序方式: 共有167条查询结果,搜索用时 15 毫秒
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Tiago Leo Mingxun Wang Nathan Moss Ricardo da Silva Jon Sanders Sergey Nurk Alexey Gurevich Gregory Humphrey Raphael Reher Qiyun Zhu Pedro Belda-Ferre Evgenia Glukhov Syrena Whitner Kelsey L. Alexander Robert Rex Pavel Pevzner Pieter C. Dorrestein Rob Knight Nuno Bandeira William H. Gerwick Lena Gerwick 《Marine drugs》2021,19(1)
Microbial natural products are important for the understanding of microbial interactions, chemical defense and communication, and have also served as an inspirational source for numerous pharmaceutical drugs. Tropical marine cyanobacteria have been highlighted as a great source of new natural products, however, few reports have appeared wherein a multi-omics approach has been used to study their natural products potential (i.e., reports are often focused on an individual natural product and its biosynthesis). This study focuses on describing the natural product genetic potential as well as the expressed natural product molecules in benthic tropical cyanobacteria. We collected from several sites around the world and sequenced the genomes of 24 tropical filamentous marine cyanobacteria. The informatics program antiSMASH was used to annotate the major classes of gene clusters. BiG-SCAPE phylum-wide analysis revealed the most promising strains for natural product discovery among these cyanobacteria. LCMS/MS-based metabolomics highlighted the most abundant molecules and molecular classes among 10 of these marine cyanobacterial samples. We observed that despite many genes encoding for peptidic natural products, peptides were not as abundant as lipids and lipopeptides in the chemical extracts. Our results highlight a number of highly interesting biosynthetic gene clusters for genome mining among these cyanobacterial samples. 相似文献
144.
Maxwell C. Wilson Xiao-Yong Chen Richard T. Corlett Raphael K. Didham Ping Ding Robert D. Holt Marcel Holyoak Guang Hu Alice C. Hughes Lin Jiang William F. Laurance Jiajia Liu Stuart L. Pimm Scott K. Robinson Sabrina E. Russo Xingfeng Si David S. Wilcove Jianguo Wu Mingjian Yu 《Landscape Ecology》2016,31(2):219-227
145.
Maxwell C. Wilson Xiao-Yong Chen Richard T. Corlett Raphael K. Didham Ping Ding Robert D. Holt Marcel Holyoak Guang Hu Alice C. Hughes Lin Jiang William F. Laurance Jiajia Liu Stuart L. Pimm Scott K. Robinson Sabrina E. Russo Xingfeng Si David S. Wilcove Jianguo Wu Mingjian Yu 《Landscape Ecology》2016,31(2):229-230
146.
Aimone Porri Michael Betz Kathryn Seebruck Michael Knapp Philipp Johnen Matthias Witschel Raphael Aponte Rex Liebl Patrick J. Tranel Jens Lerchl 《Pest management science》2023,79(2):507-519
BACKGROUND
Target site resistance to herbicides that inhibit protoporphyrinogen IX oxidase (PPO; EC 1.3.3.4) has been described mainly in broadleaf weeds based on mutations in the gene designated protoporphyrinogen oxidase 2 (PPO2) and in one monocot weed species in protoporphyrinogen oxidase 1 (PPO1). To control PPO target site resistant weeds in future it is important to design new PPO-inhibiting herbicides that can control problematic weeds expressing mutant PPO enzymes. In this study, we assessed the efficacy of a new triazinone-type inhibitor, trifludimoxazin, to inhibit PPO2 enzymes carrying target site mutations in comparison with three widely used PPO-inhibiting herbicides.RESULTS
Mutated Amaranthus spp. PPO2 enzymes were expressed in Escherichia coli, purified and measured biochemically for activity and inhibition kinetics, and used for complementation experiments in an E. coli hemG mutant that lacks the corresponding microbial PPO gene function. In addition, we used ectopic expression in Arabidopsis and structural PPO protein modeling to support the enzyme inhibition study. The generated data strongly suggest that trifludimoxazin is a strong inhibitor both at the enzyme level and in transgenics Arabidopsis ectopically expressing PPO2 target site mutations.CONCLUSION
Trifludimoxazin is a potent PPO-inhibiting herbicide that inhibits various PPO2 enzymes carrying target site mutations and could be used as a chemical-based control strategy to mitigate the widespread occurrence of PPO target site resistance as well as weeds that have evolved resistance to other herbicide mode of actions. © 2022 BASF SE and The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry. 相似文献147.
The vegetative and reproductive performances of ‘Coscia’ pear (Pyrus communis L.) grown on nine rootstocks [OHF 69, OHF 97, OHF 217, OHF 333, OHF 513 and BP 1 (P. communis), clonal seedling (Davis AxB) of Pyrus betulifolia and quince BA 29 and EMA (Cydonia oblonga)] were compared during a 9-year period. The trial was conducted at the Experimental Station ‘Avnei Eitan’ in northern Israel (elevation 400 m above sea level, a.s.l.), on a well-drained soil with pH 7.1. Trees were planted in December 1998, spaced at 4.0 m × 2.0 m and trained with a central axis. The most vigorous trees were on P. betulifolia seedlings, followed by the four OHF rootstock (69, 97, 333, 513) and BP 1 (with no significant difference between them). All the above rootstocks demonstrated greater vigor than OHF 217 and quince BA 29 or EMA. The highest cumulative yields per tree were harvested from trees on the four OHF rootstocks (69, 97, 333, 513) and P. betulifolia followed by the BP 1. The two quince rootstocks, as well as OHF 217, had the lowest cumulative yield and the lowest yield of large fruit. A positive correlation was found between the vigor of the tree, as affected by the rootstock, and both the total yield and the fruit size. We conclude that in a warm climate, yield efficiency is not the only parameter that should be taken into account, and building a strong tree for a weak cultivar is the first requirement for establishing an orchard. 相似文献
148.
Nitschke Craig R. Trouvé Raphael Lumsden Linda F. Bennett Lauren T. Fedrigo Melissa Robinson Andrew P. Baker Patrick J. 《Landscape Ecology》2020,35(7):1553-1570
Landscape Ecology - Effective conservation planning for species depends on vegetation models that can capture the dynamics of habitat elements across both spatial and temporal domains.... 相似文献
149.
Christopher Mulanda Aura Chrisphine S. Nyamweya James M. Njiru Cyprian Odoli Safina Musa Zachary Ogari Richard Abila Raphael Okeyo Robert Oketch 《Fisheries Management and Ecology》2019,26(2):141-152
Fisheries management uses important fish market information and information from Communication Technology (ICT) to improve fish trade by identifying inefficiencies, inequity and post‐harvest losses. The current study reports fisheries output using ICT at major landing sites and markets in Kenya and Uganda from the Kenya Marine and Fisheries Research Institute (KMFRI) Enhanced Fish Market Information Service (EFMIS) database for 2009 – 2017. Catch assessment survey data validated the use of market data in drawing conclusions. Regional Frame Survey data provided information before EFMIS, enabling comparisons of fish trade costings. The average quantity of fish traded in Kenya depended on seasons of active lake fishing, which occurs in January – March and August – October, while Uganda had an irregular pattern associated with fish trade throughout the year. The quantity of fish traded weekly depended on the average price of fish. Lower sales margins during the EFMIS project showed the merits of information sharing using ICT platforms for efficient and equitable fish trade. Such evaluation of fish market information is useful in fish trade policy formulation and for fisheries management and ecological sustainability in rural and peri‐urban communities. 相似文献
150.